A novel helper qPCR system for platinum detection via Pt-DNA coordination
A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Seve...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Cai, Sheng [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019transfer abstract |
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| Schlagwörter: |
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| Umfang: |
7 |
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| Übergeordnetes Werk: |
Enthalten in: Neuro-Brucellosis - Gouider, R. ELSEVIER, 2015, an international journal devoted to all branches of analytical chemistry, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:1050 ; year:2019 ; day:7 ; month:03 ; pages:154-160 ; extent:7 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.aca.2018.11.007 |
|---|
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ELV045475806 |
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| 520 | |a A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. | ||
| 520 | |a A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. | ||
| 650 | 7 | |a Helper qPCR platform |2 Elsevier | |
| 650 | 7 | |a Platinum-responsive on/off switch |2 Elsevier | |
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| 650 | 7 | |a Pt-DNA coordination |2 Elsevier | |
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| 700 | 1 | |a Xu, Mingcheng |4 oth | |
| 700 | 1 | |a Abdullah AL-maskri, Abdu Ahmed |4 oth | |
| 700 | 1 | |a Jung, Cheulhee |4 oth | |
| 700 | 1 | |a Zeng, Su |4 oth | |
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10.1016/j.aca.2018.11.007 doi GBV00000000000492.pica (DE-627)ELV045475806 (ELSEVIER)S0003-2670(18)31334-5 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Cai, Sheng verfasserin aut A novel helper qPCR system for platinum detection via Pt-DNA coordination 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. Helper qPCR platform Elsevier Platinum-responsive on/off switch Elsevier Platinum detection Elsevier Pt-DNA coordination Elsevier Yang, Dan oth Tian, Xueke oth Ye, Jiawei oth Xu, Mingcheng oth Abdullah AL-maskri, Abdu Ahmed oth Jung, Cheulhee oth Zeng, Su oth Enthalten in Elsevier Science Gouider, R. ELSEVIER Neuro-Brucellosis 2015 an international journal devoted to all branches of analytical chemistry Amsterdam (DE-627)ELV013501887 volume:1050 year:2019 day:7 month:03 pages:154-160 extent:7 https://doi.org/10.1016/j.aca.2018.11.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 GBV_ILN_120 35.10 Physikalische Chemie: Allgemeines VZ AR 1050 2019 7 0307 154-160 7 |
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10.1016/j.aca.2018.11.007 doi GBV00000000000492.pica (DE-627)ELV045475806 (ELSEVIER)S0003-2670(18)31334-5 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Cai, Sheng verfasserin aut A novel helper qPCR system for platinum detection via Pt-DNA coordination 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. Helper qPCR platform Elsevier Platinum-responsive on/off switch Elsevier Platinum detection Elsevier Pt-DNA coordination Elsevier Yang, Dan oth Tian, Xueke oth Ye, Jiawei oth Xu, Mingcheng oth Abdullah AL-maskri, Abdu Ahmed oth Jung, Cheulhee oth Zeng, Su oth Enthalten in Elsevier Science Gouider, R. ELSEVIER Neuro-Brucellosis 2015 an international journal devoted to all branches of analytical chemistry Amsterdam (DE-627)ELV013501887 volume:1050 year:2019 day:7 month:03 pages:154-160 extent:7 https://doi.org/10.1016/j.aca.2018.11.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 GBV_ILN_120 35.10 Physikalische Chemie: Allgemeines VZ AR 1050 2019 7 0307 154-160 7 |
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10.1016/j.aca.2018.11.007 doi GBV00000000000492.pica (DE-627)ELV045475806 (ELSEVIER)S0003-2670(18)31334-5 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Cai, Sheng verfasserin aut A novel helper qPCR system for platinum detection via Pt-DNA coordination 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. Helper qPCR platform Elsevier Platinum-responsive on/off switch Elsevier Platinum detection Elsevier Pt-DNA coordination Elsevier Yang, Dan oth Tian, Xueke oth Ye, Jiawei oth Xu, Mingcheng oth Abdullah AL-maskri, Abdu Ahmed oth Jung, Cheulhee oth Zeng, Su oth Enthalten in Elsevier Science Gouider, R. ELSEVIER Neuro-Brucellosis 2015 an international journal devoted to all branches of analytical chemistry Amsterdam (DE-627)ELV013501887 volume:1050 year:2019 day:7 month:03 pages:154-160 extent:7 https://doi.org/10.1016/j.aca.2018.11.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 GBV_ILN_120 35.10 Physikalische Chemie: Allgemeines VZ AR 1050 2019 7 0307 154-160 7 |
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10.1016/j.aca.2018.11.007 doi GBV00000000000492.pica (DE-627)ELV045475806 (ELSEVIER)S0003-2670(18)31334-5 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Cai, Sheng verfasserin aut A novel helper qPCR system for platinum detection via Pt-DNA coordination 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. Helper qPCR platform Elsevier Platinum-responsive on/off switch Elsevier Platinum detection Elsevier Pt-DNA coordination Elsevier Yang, Dan oth Tian, Xueke oth Ye, Jiawei oth Xu, Mingcheng oth Abdullah AL-maskri, Abdu Ahmed oth Jung, Cheulhee oth Zeng, Su oth Enthalten in Elsevier Science Gouider, R. ELSEVIER Neuro-Brucellosis 2015 an international journal devoted to all branches of analytical chemistry Amsterdam (DE-627)ELV013501887 volume:1050 year:2019 day:7 month:03 pages:154-160 extent:7 https://doi.org/10.1016/j.aca.2018.11.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 GBV_ILN_120 35.10 Physikalische Chemie: Allgemeines VZ AR 1050 2019 7 0307 154-160 7 |
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10.1016/j.aca.2018.11.007 doi GBV00000000000492.pica (DE-627)ELV045475806 (ELSEVIER)S0003-2670(18)31334-5 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Cai, Sheng verfasserin aut A novel helper qPCR system for platinum detection via Pt-DNA coordination 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. Helper qPCR platform Elsevier Platinum-responsive on/off switch Elsevier Platinum detection Elsevier Pt-DNA coordination Elsevier Yang, Dan oth Tian, Xueke oth Ye, Jiawei oth Xu, Mingcheng oth Abdullah AL-maskri, Abdu Ahmed oth Jung, Cheulhee oth Zeng, Su oth Enthalten in Elsevier Science Gouider, R. ELSEVIER Neuro-Brucellosis 2015 an international journal devoted to all branches of analytical chemistry Amsterdam (DE-627)ELV013501887 volume:1050 year:2019 day:7 month:03 pages:154-160 extent:7 https://doi.org/10.1016/j.aca.2018.11.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_40 GBV_ILN_120 35.10 Physikalische Chemie: Allgemeines VZ AR 1050 2019 7 0307 154-160 7 |
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A novel helper qPCR system for platinum detection via Pt-DNA coordination |
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Cai, Sheng |
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a novel helper qpcr system for platinum detection via pt-dna coordination |
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A novel helper qPCR system for platinum detection via Pt-DNA coordination |
| abstract |
A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. |
| abstractGer |
A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. |
| abstract_unstemmed |
A novel real-time polymerase chain reaction (qPCR) platform for the simple and robust detection of platinum is described for the first time. Compared with conventional qPCR, a helper template, which is related to the active template for performing qPCR, was introduced in our helper qPCR system. Several guanine (G) bases were introduced in the helper template to obtain a platinum-responsive on/off switch based on G-Pt-G coordination. Because of the helper template, a slight change in platinum concentration would significantly change the signal in the qPCR. This novel helper qPCR technique easily detects platinum with high sensitivity (1 ng/mL) and selectivity over other metal ions. Therefore, it will be a promising technique for the detection of platinum in biomedical and environmental samples. |
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A novel helper qPCR system for platinum detection via Pt-DNA coordination |
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Yang, Dan Tian, Xueke Ye, Jiawei Xu, Mingcheng Abdullah AL-maskri, Abdu Ahmed Jung, Cheulhee Zeng, Su |
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