Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Na<ce:inf loc="post">v</ce:inf>1.1 activators

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Gespeichert in:

Autor*in:	Miyazaki, Tohru [verfasserIn] Kawasaki, Masanori Suzuki, Atsushi Ito, Yuki Imanishi, Akio Maru, Takamitsu Kawamoto, Tomohiro Koike, Tatsuki

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Dravet syndrome BBB penetration v1.1 activator">Nav1.1 activator Voltage-gated sodium channels Slow current decay of inactivation

Umfang:	6

Übergeordnetes Werk:	Enthalten in: Feeding European sea bass ( - Torrecillas, S. ELSEVIER, 2018, a Tetrahedron publication for rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry, bioinorganic chemistry and related disciplines, Amsterdam [u.a.]
Übergeordnetes Werk:	volume:29 ; year:2019 ; number:6 ; day:15 ; month:03 ; pages:815-820 ; extent:6

Links:	Volltext

DOI / URN:	10.1016/j.bmcl.2019.01.023

Katalog-ID:	ELV045801592

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author	Miyazaki, Tohru
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topic_title	630 VZ 22 ssgn 46.00 bkl Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Na<ce:inf loc="post">v</ce:inf>1.1 activators Dravet syndrome Elsevier BBB penetration Elsevier Na<ce:inf loc="post">v</ce:inf>1.1 activator Elsevier Voltage-gated sodium channels Elsevier Slow current decay of inactivation Elsevier
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title_auth	Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Na<ce:inf loc="post">v</ce:inf>1.1 activators
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title_short	Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Na<ce:inf loc="post">v</ce:inf>1.1 activators
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Discovery of novel 4-phenyl-2-(pyrrolidinyl)nicotinamide derivatives as potent Na<ce:inf loc="post">v</ce:inf>1.1 activators

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