Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats
• Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokine...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zhi, Haijuan [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Umfang: |
14 |
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| Übergeordnetes Werk: |
Enthalten in: Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures - Gölbaşι, Gülcan ELSEVIER, 2023, the official analytical journal of the American Association of Pharmaceutical Scientists, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:166 ; year:2019 ; day:20 ; month:03 ; pages:52-65 ; extent:14 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.jpba.2018.12.043 |
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| 520 | |a • Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokinetic behaviors in acute myocardial ischemia (AMI) and sham rats. • Compared with AMI rats after oral PNE, AUC0-tvalues of target compounds were significantly increased after oral administration of DQTT. • SA could improve the bioavailability of notoginsenosides in AMI ratsafter oral DQTT. | ||
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10.1016/j.jpba.2018.12.043 doi GBV00000000000525.pica (DE-627)ELV045836477 (ELSEVIER)S0731-7085(18)32130-7 DE-627 ger DE-627 rakwb eng 630 640 VZ 58.34 bkl 48.61 bkl Zhi, Haijuan verfasserin aut Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats 2019 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokinetic behaviors in acute myocardial ischemia (AMI) and sham rats. • Compared with AMI rats after oral PNE, AUC0-tvalues of target compounds were significantly increased after oral administration of DQTT. • SA could improve the bioavailability of notoginsenosides in AMI ratsafter oral DQTT. UHPLC-TQ/MS Elsevier Pharmacokinetics Elsevier Acute myocardial ischemic Elsevier Herb-herb interaction Elsevier Danqi Tongmai tablet Elsevier Deng, Yanping oth Yan, Bingpeng oth Li, Zhenwei oth Han, Sumei oth Zhang, Yibei oth Hou, Jinjun oth Wu, Wanying oth Guo, Dean oth Enthalten in Science Direct Gölbaşι, Gülcan ELSEVIER Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures 2023 the official analytical journal of the American Association of Pharmaceutical Scientists New York, NY [u.a.] (DE-627)ELV009872493 volume:166 year:2019 day:20 month:03 pages:52-65 extent:14 https://doi.org/10.1016/j.jpba.2018.12.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 58.34 Lebensmitteltechnologie VZ 48.61 Tierernährung Tierfutter VZ AR 166 2019 20 0320 52-65 14 |
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10.1016/j.jpba.2018.12.043 doi GBV00000000000525.pica (DE-627)ELV045836477 (ELSEVIER)S0731-7085(18)32130-7 DE-627 ger DE-627 rakwb eng 630 640 VZ 58.34 bkl 48.61 bkl Zhi, Haijuan verfasserin aut Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats 2019 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokinetic behaviors in acute myocardial ischemia (AMI) and sham rats. • Compared with AMI rats after oral PNE, AUC0-tvalues of target compounds were significantly increased after oral administration of DQTT. • SA could improve the bioavailability of notoginsenosides in AMI ratsafter oral DQTT. UHPLC-TQ/MS Elsevier Pharmacokinetics Elsevier Acute myocardial ischemic Elsevier Herb-herb interaction Elsevier Danqi Tongmai tablet Elsevier Deng, Yanping oth Yan, Bingpeng oth Li, Zhenwei oth Han, Sumei oth Zhang, Yibei oth Hou, Jinjun oth Wu, Wanying oth Guo, Dean oth Enthalten in Science Direct Gölbaşι, Gülcan ELSEVIER Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures 2023 the official analytical journal of the American Association of Pharmaceutical Scientists New York, NY [u.a.] (DE-627)ELV009872493 volume:166 year:2019 day:20 month:03 pages:52-65 extent:14 https://doi.org/10.1016/j.jpba.2018.12.043 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 58.34 Lebensmitteltechnologie VZ 48.61 Tierernährung Tierfutter VZ AR 166 2019 20 0320 52-65 14 |
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Enthalten in Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures New York, NY [u.a.] volume:166 year:2019 day:20 month:03 pages:52-65 extent:14 |
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Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures |
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Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats |
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Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats |
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Zhi, Haijuan |
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Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures |
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Monitoring the changes in physicochemical, sensory properties and microbiota of village-type homemade yoghurts along three consecutive back-slopping procedures |
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600 - Technology |
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2019 |
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Zhi, Haijuan |
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Zhi, Haijuan |
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10.1016/j.jpba.2018.12.043 |
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630 640 |
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study on the herb-herb interaction of danqi tongmai tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats |
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Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats |
| abstract |
• Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokinetic behaviors in acute myocardial ischemia (AMI) and sham rats. • Compared with AMI rats after oral PNE, AUC0-tvalues of target compounds were significantly increased after oral administration of DQTT. • SA could improve the bioavailability of notoginsenosides in AMI ratsafter oral DQTT. |
| abstractGer |
• Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokinetic behaviors in acute myocardial ischemia (AMI) and sham rats. • Compared with AMI rats after oral PNE, AUC0-tvalues of target compounds were significantly increased after oral administration of DQTT. • SA could improve the bioavailability of notoginsenosides in AMI ratsafter oral DQTT. |
| abstract_unstemmed |
• Danqi Tongmai tablet (DQTT), an innovative TCM formula under clinical trials, is composed of salvianolic acids (SA) and panax notoginsenosides (PNE) for the treatment of coronary heart disease and angina pectoris. • The herb-herb interaction mechanism of DQTT was explored based on the pharmacokinetic behaviors in acute myocardial ischemia (AMI) and sham rats. • Compared with AMI rats after oral PNE, AUC0-tvalues of target compounds were significantly increased after oral administration of DQTT. • SA could improve the bioavailability of notoginsenosides in AMI ratsafter oral DQTT. |
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Study on the herb-herb interaction of Danqi Tongmai Tablet based on the pharmacokinetics of twelve notoginsenoides in acute myocardial ischemia and sham rats |
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https://doi.org/10.1016/j.jpba.2018.12.043 |
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Deng, Yanping Yan, Bingpeng Li, Zhenwei Han, Sumei Zhang, Yibei Hou, Jinjun Wu, Wanying Guo, Dean |
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Deng, Yanping Yan, Bingpeng Li, Zhenwei Han, Sumei Zhang, Yibei Hou, Jinjun Wu, Wanying Guo, Dean |
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