Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development
Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immun...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
O’Brien, Eóin C. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019transfer abstract |
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| Schlagwörter: |
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| Umfang: |
14 |
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| Übergeordnetes Werk: |
Enthalten in: Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements - 2011transfer abstract, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:25 ; year:2019 ; number:3 ; pages:171-184 ; extent:14 |
| Links: |
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| DOI / URN: |
10.1016/j.molmed.2018.12.010 |
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| 520 | |a Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. | ||
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10.1016/j.molmed.2018.12.010 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000896.pica (DE-627)ELV045954380 (ELSEVIER)S1471-4914(19)30002-4 DE-627 ger DE-627 rakwb eng 050 VZ 550 VZ 660 VZ 660 VZ 530 600 670 VZ 51.00 bkl O’Brien, Eóin C. verfasserin aut Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development 2019transfer abstract 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. MAIT cells Elsevier γδ cells Elsevier innate lymphoid cells Elsevier Staphylococcus aureus Elsevier McLoughlin, Rachel M. oth Enthalten in Elsevier Science Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements 2011transfer abstract Amsterdam [u.a.] (DE-627)ELV026173794 volume:25 year:2019 number:3 pages:171-184 extent:14 https://doi.org/10.1016/j.molmed.2018.12.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_73 GBV_ILN_252 51.00 Werkstoffkunde: Allgemeines VZ AR 25 2019 3 171-184 14 |
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10.1016/j.molmed.2018.12.010 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000896.pica (DE-627)ELV045954380 (ELSEVIER)S1471-4914(19)30002-4 DE-627 ger DE-627 rakwb eng 050 VZ 550 VZ 660 VZ 660 VZ 530 600 670 VZ 51.00 bkl O’Brien, Eóin C. verfasserin aut Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development 2019transfer abstract 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. MAIT cells Elsevier γδ cells Elsevier innate lymphoid cells Elsevier Staphylococcus aureus Elsevier McLoughlin, Rachel M. oth Enthalten in Elsevier Science Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements 2011transfer abstract Amsterdam [u.a.] (DE-627)ELV026173794 volume:25 year:2019 number:3 pages:171-184 extent:14 https://doi.org/10.1016/j.molmed.2018.12.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_73 GBV_ILN_252 51.00 Werkstoffkunde: Allgemeines VZ AR 25 2019 3 171-184 14 |
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10.1016/j.molmed.2018.12.010 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000896.pica (DE-627)ELV045954380 (ELSEVIER)S1471-4914(19)30002-4 DE-627 ger DE-627 rakwb eng 050 VZ 550 VZ 660 VZ 660 VZ 530 600 670 VZ 51.00 bkl O’Brien, Eóin C. verfasserin aut Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development 2019transfer abstract 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. MAIT cells Elsevier γδ cells Elsevier innate lymphoid cells Elsevier Staphylococcus aureus Elsevier McLoughlin, Rachel M. oth Enthalten in Elsevier Science Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements 2011transfer abstract Amsterdam [u.a.] (DE-627)ELV026173794 volume:25 year:2019 number:3 pages:171-184 extent:14 https://doi.org/10.1016/j.molmed.2018.12.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_73 GBV_ILN_252 51.00 Werkstoffkunde: Allgemeines VZ AR 25 2019 3 171-184 14 |
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10.1016/j.molmed.2018.12.010 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000896.pica (DE-627)ELV045954380 (ELSEVIER)S1471-4914(19)30002-4 DE-627 ger DE-627 rakwb eng 050 VZ 550 VZ 660 VZ 660 VZ 530 600 670 VZ 51.00 bkl O’Brien, Eóin C. verfasserin aut Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development 2019transfer abstract 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. MAIT cells Elsevier γδ cells Elsevier innate lymphoid cells Elsevier Staphylococcus aureus Elsevier McLoughlin, Rachel M. oth Enthalten in Elsevier Science Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements 2011transfer abstract Amsterdam [u.a.] (DE-627)ELV026173794 volume:25 year:2019 number:3 pages:171-184 extent:14 https://doi.org/10.1016/j.molmed.2018.12.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_73 GBV_ILN_252 51.00 Werkstoffkunde: Allgemeines VZ AR 25 2019 3 171-184 14 |
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10.1016/j.molmed.2018.12.010 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000896.pica (DE-627)ELV045954380 (ELSEVIER)S1471-4914(19)30002-4 DE-627 ger DE-627 rakwb eng 050 VZ 550 VZ 660 VZ 660 VZ 530 600 670 VZ 51.00 bkl O’Brien, Eóin C. verfasserin aut Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development 2019transfer abstract 14 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. MAIT cells Elsevier γδ cells Elsevier innate lymphoid cells Elsevier Staphylococcus aureus Elsevier McLoughlin, Rachel M. oth Enthalten in Elsevier Science Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements 2011transfer abstract Amsterdam [u.a.] (DE-627)ELV026173794 volume:25 year:2019 number:3 pages:171-184 extent:14 https://doi.org/10.1016/j.molmed.2018.12.010 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_73 GBV_ILN_252 51.00 Werkstoffkunde: Allgemeines VZ AR 25 2019 3 171-184 14 |
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Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development |
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O’Brien, Eóin C. |
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Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements |
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Ocean sand ridge signatures in the Bohai Sea observed by satellite ocean color and synthetic aperture radar measurements |
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eng |
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000 - Computer science, information & general works 500 - Science 600 - Technology |
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2019 |
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O’Brien, Eóin C. |
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O’Brien, Eóin C. |
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10.1016/j.molmed.2018.12.010 |
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050 550 660 530 600 670 |
| title_sort |
considering the ‘alternatives’ for next-generation anti-staphylococcus aureus vaccine development |
| title_auth |
Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development |
| abstract |
Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. |
| abstractGer |
Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. |
| abstract_unstemmed |
Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular focus on vaccine development. S. aureus vaccines that target humoral immunity alone do not provide sufficient protection from all disease phenotypes associated with this pathogen. Recent studies have identified the requirement for cellular immunity to provide a robust immune response to this infection. Driving conventional T cell responses has therefore become the focus of intense research in this area. Recently described ‘alternative’ T cells could provide a novel strategy for improving therapeutic efficacy and success in next-generation anti-S. aureus vaccine design. |
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| title_short |
Considering the ‘Alternatives’ for Next-Generation Anti-Staphylococcus aureus Vaccine Development |
| url |
https://doi.org/10.1016/j.molmed.2018.12.010 |
| remote_bool |
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| author2 |
McLoughlin, Rachel M. |
| author2Str |
McLoughlin, Rachel M. |
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| up_date |
2024-07-06T18:56:05.686Z |
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