Direct and antibody-dependent cell-mediated cytotoxicity of head and neck squamous cell carcinoma cells by high-affinity natural killer cells
• haNKs are an off-the-shelf cellular therapy that kill head and neck cancer cells. • Cetuximab and Avelumab enhance tumor cell killing by haNKs through ADCC. • Ionizing radiation may enhance ADCC through increased expression of antibody targets. • haNKs plus cetuximab or avelumab warrant evaluation...
Ausführliche Beschreibung
Autor*in: |
Friedman, Jay [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Schlagwörter: |
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Umfang: |
7 |
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Übergeordnetes Werk: |
Enthalten in: Anti-anaerobic activity of a new β-lactamase inhibitor NXL104 in combination with β-lactams and metronidazole - 2012transfer abstract, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:90 ; year:2019 ; pages:38-44 ; extent:7 |
Links: |
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DOI / URN: |
10.1016/j.oraloncology.2019.01.017 |
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ELV045976597 |
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direct and antibody-dependent cell-mediated cytotoxicity of head and neck squamous cell carcinoma cells by high-affinity natural killer cells |
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Direct and antibody-dependent cell-mediated cytotoxicity of head and neck squamous cell carcinoma cells by high-affinity natural killer cells |
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• haNKs are an off-the-shelf cellular therapy that kill head and neck cancer cells. • Cetuximab and Avelumab enhance tumor cell killing by haNKs through ADCC. • Ionizing radiation may enhance ADCC through increased expression of antibody targets. • haNKs plus cetuximab or avelumab warrant evaluation in clinical trials for HNSCC. |
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• haNKs are an off-the-shelf cellular therapy that kill head and neck cancer cells. • Cetuximab and Avelumab enhance tumor cell killing by haNKs through ADCC. • Ionizing radiation may enhance ADCC through increased expression of antibody targets. • haNKs plus cetuximab or avelumab warrant evaluation in clinical trials for HNSCC. |
abstract_unstemmed |
• haNKs are an off-the-shelf cellular therapy that kill head and neck cancer cells. • Cetuximab and Avelumab enhance tumor cell killing by haNKs through ADCC. • Ionizing radiation may enhance ADCC through increased expression of antibody targets. • haNKs plus cetuximab or avelumab warrant evaluation in clinical trials for HNSCC. |
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GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-MAT |
title_short |
Direct and antibody-dependent cell-mediated cytotoxicity of head and neck squamous cell carcinoma cells by high-affinity natural killer cells |
url |
https://doi.org/10.1016/j.oraloncology.2019.01.017 |
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author2 |
Padget, Michelle Lee, John Schlom, Jeffrey Hodge, James Allen, Clint |
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Padget, Michelle Lee, John Schlom, Jeffrey Hodge, James Allen, Clint |
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doi_str |
10.1016/j.oraloncology.2019.01.017 |
up_date |
2024-07-06T19:00:07.469Z |
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