WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS
It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Chen, Xiangning [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
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2019transfer abstract |
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2 |
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Enthalten in: Temperature-dependence laws of absorption line shape parameters of the CO - Wilzewski, J.S. ELSEVIER, 2017, ENP : the journal of the European College of Neuropsychopharmacology, Amsterdam |
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volume:29 ; year:2019 ; pages:868-869 ; extent:2 |
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| DOI / URN: |
10.1016/j.euroneuro.2017.08.158 |
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| 520 | |a It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. | ||
| 520 | |a It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. | ||
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10.1016/j.euroneuro.2017.08.158 doi GBV00000000000688.pica (DE-627)ELV046224572 (ELSEVIER)S0924-977X(17)30622-3 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Chen, Xiangning verfasserin aut WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS 2019transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. Chen, Jingchun oth Wu, Jain-Shin oth Mize, Travis oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:868-869 extent:2 https://doi.org/10.1016/j.euroneuro.2017.08.158 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 868-869 2 29.2019, S868-, (2 S.) |
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10.1016/j.euroneuro.2017.08.158 doi GBV00000000000688.pica (DE-627)ELV046224572 (ELSEVIER)S0924-977X(17)30622-3 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Chen, Xiangning verfasserin aut WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS 2019transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. Chen, Jingchun oth Wu, Jain-Shin oth Mize, Travis oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:868-869 extent:2 https://doi.org/10.1016/j.euroneuro.2017.08.158 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 868-869 2 29.2019, S868-, (2 S.) |
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10.1016/j.euroneuro.2017.08.158 doi GBV00000000000688.pica (DE-627)ELV046224572 (ELSEVIER)S0924-977X(17)30622-3 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Chen, Xiangning verfasserin aut WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS 2019transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. Chen, Jingchun oth Wu, Jain-Shin oth Mize, Travis oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:868-869 extent:2 https://doi.org/10.1016/j.euroneuro.2017.08.158 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 868-869 2 29.2019, S868-, (2 S.) |
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10.1016/j.euroneuro.2017.08.158 doi GBV00000000000688.pica (DE-627)ELV046224572 (ELSEVIER)S0924-977X(17)30622-3 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Chen, Xiangning verfasserin aut WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS 2019transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. Chen, Jingchun oth Wu, Jain-Shin oth Mize, Travis oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:868-869 extent:2 https://doi.org/10.1016/j.euroneuro.2017.08.158 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 868-869 2 29.2019, S868-, (2 S.) |
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10.1016/j.euroneuro.2017.08.158 doi GBV00000000000688.pica (DE-627)ELV046224572 (ELSEVIER)S0924-977X(17)30622-3 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Chen, Xiangning verfasserin aut WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS 2019transfer abstract 2 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. Chen, Jingchun oth Wu, Jain-Shin oth Mize, Travis oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:868-869 extent:2 https://doi.org/10.1016/j.euroneuro.2017.08.158 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 868-869 2 29.2019, S868-, (2 S.) |
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WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS |
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It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. |
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It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. |
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It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV046224572</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626013308.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">191021s2019 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.euroneuro.2017.08.158</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">GBV00000000000688.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV046224572</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0924-977X(17)30622-3</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">33.00</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Chen, Xiangning</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">WHOLE GENOME SEQUENCING OF SCHIZOPHRENIA FAMILIES WITH MULTIPLE AFFECTED INDIVIDUALS</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2019transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">2</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">It has long been established that schizophrenia is highly heritable and family history is a reliable predictor for the disorder. However, both GWAS and exome sequencing studies fail to answer the question what genetic variants constitute family history. While it is generally believed that cases from families with multiple affected individuals have higher genetic risk loading, it is not clear to what extent and where do these cases differ from sporadic cases where there is no apparent family history of mental disorders. Whole genome sequencing of cases from families with multiple affected individuals may help to answer this question.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chen, Jingchun</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wu, Jain-Shin</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mize, Travis</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Wilzewski, J.S. 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