IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA
During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this contex...
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| Autor*in: |
Esteller-Cucala, Paula [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019transfer abstract |
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| Übergeordnetes Werk: |
Enthalten in: Temperature-dependence laws of absorption line shape parameters of the CO - Wilzewski, J.S. ELSEVIER, 2017, ENP : the journal of the European College of Neuropsychopharmacology, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:29 ; year:2019 ; pages:889 |
| Links: |
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| DOI / URN: |
10.1016/j.euroneuro.2017.08.194 |
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| 520 | |a During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. | ||
| 520 | |a During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. | ||
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10.1016/j.euroneuro.2017.08.194 doi GBV00000000000688.pica (DE-627)ELV046224831 (ELSEVIER)S0924-977X(17)30658-2 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Esteller-Cucala, Paula verfasserin aut IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. Maceda, Iago oth Demontis, Ditte oth Børglum, Anders D. oth Neale, Benjamin oth Faraone, Stephen V. oth Cormand, Bru oth Lao, Oscar oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:889 https://doi.org/10.1016/j.euroneuro.2017.08.194 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 889 29.2019, S889- |
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10.1016/j.euroneuro.2017.08.194 doi GBV00000000000688.pica (DE-627)ELV046224831 (ELSEVIER)S0924-977X(17)30658-2 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Esteller-Cucala, Paula verfasserin aut IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. Maceda, Iago oth Demontis, Ditte oth Børglum, Anders D. oth Neale, Benjamin oth Faraone, Stephen V. oth Cormand, Bru oth Lao, Oscar oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:889 https://doi.org/10.1016/j.euroneuro.2017.08.194 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 889 29.2019, S889- |
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10.1016/j.euroneuro.2017.08.194 doi GBV00000000000688.pica (DE-627)ELV046224831 (ELSEVIER)S0924-977X(17)30658-2 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Esteller-Cucala, Paula verfasserin aut IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. Maceda, Iago oth Demontis, Ditte oth Børglum, Anders D. oth Neale, Benjamin oth Faraone, Stephen V. oth Cormand, Bru oth Lao, Oscar oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:889 https://doi.org/10.1016/j.euroneuro.2017.08.194 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 889 29.2019, S889- |
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10.1016/j.euroneuro.2017.08.194 doi GBV00000000000688.pica (DE-627)ELV046224831 (ELSEVIER)S0924-977X(17)30658-2 DE-627 ger DE-627 rakwb eng 530 VZ 33.00 bkl Esteller-Cucala, Paula verfasserin aut IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. Maceda, Iago oth Demontis, Ditte oth Børglum, Anders D. oth Neale, Benjamin oth Faraone, Stephen V. oth Cormand, Bru oth Lao, Oscar oth Enthalten in Elsevier Wilzewski, J.S. ELSEVIER Temperature-dependence laws of absorption line shape parameters of the CO 2017 ENP : the journal of the European College of Neuropsychopharmacology Amsterdam (DE-627)ELV000200816 volume:29 year:2019 pages:889 https://doi.org/10.1016/j.euroneuro.2017.08.194 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 33.00 Physik: Allgemeines VZ AR 29 2019 889 29.2019, S889- |
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IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA |
| abstract |
During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. |
| abstractGer |
During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. |
| abstract_unstemmed |
During the human Diaspora out of Africa, Anatomically Modern Humans (AMH) adapted to the new environments they encountered. On top, adaptation process could have been fueled by interbreeding with homo archaic species -such as Neanderthal and Denisovan- present at that time in Eurasia. In this context of natural adaptation, Attention-Deficit/Hyperactivity Disorder (ADHD) poses an interesting evolutionary paradox: despite being associated with significant impairment, morbidity and increased rates of mortality, it is a highly prevalent phenotype. Being a highly heritable trait, several selective hypotheses have been proposed to explain the prevalence of this phenotype. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| title_short |
IDENTIFICATION OF POLYGENIC ADAPTATION IN ATTENTION-DEFICIT/HYPERACTIVITY DISORDER USING GWAS DATA |
| url |
https://doi.org/10.1016/j.euroneuro.2017.08.194 |
| remote_bool |
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| author2 |
Maceda, Iago Demontis, Ditte Børglum, Anders D. Neale, Benjamin Faraone, Stephen V. Cormand, Bru Lao, Oscar |
| author2Str |
Maceda, Iago Demontis, Ditte Børglum, Anders D. Neale, Benjamin Faraone, Stephen V. Cormand, Bru Lao, Oscar |
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ELV000200816 |
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| doi_str |
10.1016/j.euroneuro.2017.08.194 |
| up_date |
2024-07-06T19:39:45.143Z |
| _version_ |
1803859824627154944 |
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