The inhibition of adipogenesis via an <ce:italic>in vitro</ce:italic> assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method
Schematic design showing the adipogenic differentiation assay. In this method, the cells are maintained for 14 days in contact with different test substance concentrations. This strategy allows the repeated dose approach. In this way, it is possible to visualize the influence of substances during th...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Abud, Ana Paula Ressett [verfasserIn] Corrêa, Natássia Caroline Resende |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Umfang: |
11 |
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| Übergeordnetes Werk: |
Enthalten in: Toxicology letters - Chen, Yun-Ru ELSEVIER, 2019, an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:311 ; year:2019 ; day:1 ; month:09 ; pages:80-90 ; extent:11 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.toxlet.2019.04.009 |
|---|
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ELV046873198 |
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The inhibition of adipogenesis via an <ce:italic>in vitro</ce:italic> assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method |
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The inhibition of adipogenesis via an <ce:italic>in vitro</ce:italic> assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method |
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inhibition of adipogenesis via an <ce:italic>in vitro</ce:italic> assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method |
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The inhibition of adipogenesis via an <ce:italic>in vitro</ce:italic> assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method |
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Schematic design showing the adipogenic differentiation assay. In this method, the cells are maintained for 14 days in contact with different test substance concentrations. This strategy allows the repeated dose approach. In this way, it is possible to visualize the influence of substances during the cell differentiation process. |
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Schematic design showing the adipogenic differentiation assay. In this method, the cells are maintained for 14 days in contact with different test substance concentrations. This strategy allows the repeated dose approach. In this way, it is possible to visualize the influence of substances during the cell differentiation process. |
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Schematic design showing the adipogenic differentiation assay. In this method, the cells are maintained for 14 days in contact with different test substance concentrations. This strategy allows the repeated dose approach. In this way, it is possible to visualize the influence of substances during the cell differentiation process. |
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The inhibition of adipogenesis via an <ce:italic>in vitro</ce:italic> assay can reduce animal use by more precisely estimating the starting dose for the acute toxic class method |
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Kuligovski, Crisciele Corrêa, Natássia Caroline Resende de Moraes, Elizabeth Cunha Penna Caruso, Rodrigo Rêgo Barros Schuck, Desirée Cigaran Brohem, Carla Abdo Dallagiovanna, Bruno de Aguiar, Alessandra Melo |
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