The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia
Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved...
Ausführliche Beschreibung
Autor*in: |
Chan, Wei Yee [verfasserIn] |
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Englisch |
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2019transfer abstract |
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Enthalten in: Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up - 2012, an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:212 ; year:2019 ; pages:43-49 ; extent:7 |
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DOI / URN: |
10.1016/j.vetimm.2019.05.002 |
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ELV047152451 |
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245 | 1 | 4 | |a The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia |
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520 | |a Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. | ||
520 | |a Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. | ||
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650 | 7 | |a Atopic dermatitis |2 Elsevier | |
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650 | 7 | |a Dogs |2 Elsevier | |
650 | 7 | |a Dust mites |2 Elsevier | |
650 | 7 | |a Der f 2 |2 Elsevier | |
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700 | 1 | |a Ajat, Mokrish |4 oth | |
700 | 1 | |a Suzuki, Rieko |4 oth | |
700 | 1 | |a Tsukui, Toshihiro |4 oth | |
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10.1016/j.vetimm.2019.05.002 doi GBV00000000000658.pica (DE-627)ELV047152451 (ELSEVIER)S0165-2427(18)30241-1 DE-627 ger DE-627 rakwb eng 610 VZ 600 670 VZ 51.00 bkl Chan, Wei Yee verfasserin aut The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. CDF Elsevier Zen-1 Elsevier Atopic dermatitis Elsevier IgE Elsevier Dogs Elsevier Dust mites Elsevier Der f 2 Elsevier Selvarajah, Gayathri Thevi oth Ajat, Mokrish oth Suzuki, Rieko oth Tsukui, Toshihiro oth Enthalten in Elsevier Science Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up 2012 an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man Amsterdam [u.a.] (DE-627)ELV011273445 volume:212 year:2019 pages:43-49 extent:7 https://doi.org/10.1016/j.vetimm.2019.05.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_21 GBV_ILN_70 51.00 Werkstoffkunde: Allgemeines VZ AR 212 2019 43-49 7 |
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10.1016/j.vetimm.2019.05.002 doi GBV00000000000658.pica (DE-627)ELV047152451 (ELSEVIER)S0165-2427(18)30241-1 DE-627 ger DE-627 rakwb eng 610 VZ 600 670 VZ 51.00 bkl Chan, Wei Yee verfasserin aut The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. CDF Elsevier Zen-1 Elsevier Atopic dermatitis Elsevier IgE Elsevier Dogs Elsevier Dust mites Elsevier Der f 2 Elsevier Selvarajah, Gayathri Thevi oth Ajat, Mokrish oth Suzuki, Rieko oth Tsukui, Toshihiro oth Enthalten in Elsevier Science Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up 2012 an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man Amsterdam [u.a.] (DE-627)ELV011273445 volume:212 year:2019 pages:43-49 extent:7 https://doi.org/10.1016/j.vetimm.2019.05.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_21 GBV_ILN_70 51.00 Werkstoffkunde: Allgemeines VZ AR 212 2019 43-49 7 |
allfields_unstemmed |
10.1016/j.vetimm.2019.05.002 doi GBV00000000000658.pica (DE-627)ELV047152451 (ELSEVIER)S0165-2427(18)30241-1 DE-627 ger DE-627 rakwb eng 610 VZ 600 670 VZ 51.00 bkl Chan, Wei Yee verfasserin aut The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. CDF Elsevier Zen-1 Elsevier Atopic dermatitis Elsevier IgE Elsevier Dogs Elsevier Dust mites Elsevier Der f 2 Elsevier Selvarajah, Gayathri Thevi oth Ajat, Mokrish oth Suzuki, Rieko oth Tsukui, Toshihiro oth Enthalten in Elsevier Science Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up 2012 an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man Amsterdam [u.a.] (DE-627)ELV011273445 volume:212 year:2019 pages:43-49 extent:7 https://doi.org/10.1016/j.vetimm.2019.05.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_21 GBV_ILN_70 51.00 Werkstoffkunde: Allgemeines VZ AR 212 2019 43-49 7 |
allfieldsGer |
10.1016/j.vetimm.2019.05.002 doi GBV00000000000658.pica (DE-627)ELV047152451 (ELSEVIER)S0165-2427(18)30241-1 DE-627 ger DE-627 rakwb eng 610 VZ 600 670 VZ 51.00 bkl Chan, Wei Yee verfasserin aut The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. CDF Elsevier Zen-1 Elsevier Atopic dermatitis Elsevier IgE Elsevier Dogs Elsevier Dust mites Elsevier Der f 2 Elsevier Selvarajah, Gayathri Thevi oth Ajat, Mokrish oth Suzuki, Rieko oth Tsukui, Toshihiro oth Enthalten in Elsevier Science Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up 2012 an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man Amsterdam [u.a.] (DE-627)ELV011273445 volume:212 year:2019 pages:43-49 extent:7 https://doi.org/10.1016/j.vetimm.2019.05.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_21 GBV_ILN_70 51.00 Werkstoffkunde: Allgemeines VZ AR 212 2019 43-49 7 |
allfieldsSound |
10.1016/j.vetimm.2019.05.002 doi GBV00000000000658.pica (DE-627)ELV047152451 (ELSEVIER)S0165-2427(18)30241-1 DE-627 ger DE-627 rakwb eng 610 VZ 600 670 VZ 51.00 bkl Chan, Wei Yee verfasserin aut The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia 2019transfer abstract 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. CDF Elsevier Zen-1 Elsevier Atopic dermatitis Elsevier IgE Elsevier Dogs Elsevier Dust mites Elsevier Der f 2 Elsevier Selvarajah, Gayathri Thevi oth Ajat, Mokrish oth Suzuki, Rieko oth Tsukui, Toshihiro oth Enthalten in Elsevier Science Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up 2012 an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man Amsterdam [u.a.] (DE-627)ELV011273445 volume:212 year:2019 pages:43-49 extent:7 https://doi.org/10.1016/j.vetimm.2019.05.002 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_21 GBV_ILN_70 51.00 Werkstoffkunde: Allgemeines VZ AR 212 2019 43-49 7 |
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detection of house dust mite <ce:italic>dermatophagoides farinae</ce:italic>, der f 2 and zen-1 allergen-specific immunoglobulin e antibodies in dogs with atopic dermatitis in malaysia |
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The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia |
abstract |
Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. |
abstractGer |
Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. |
abstract_unstemmed |
Canine atopic dermatitis (AD) is a chronic, inflammatory and pruritic allergic skin disease in dogs. House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies. |
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The detection of house dust mite <ce:italic>Dermatophagoides farinae</ce:italic>, Der f 2 and Zen-1 allergen-specific immunoglobulin E antibodies in dogs with atopic Dermatitis in Malaysia |
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House dust mites such as Dermatophagoides farinae are one of the known causative agents for the induction of canine AD worldwide. D. farinae protein Der f 2 is known as an important allergen involved in canine AD and recently, Zen-1 has also been identified as an allergenic protein. There is limited information on the prevalence and role of allergen sensitization to crude D. farinae extract (CDF), Der f 2 and Zen-1 among dogs diagnosed with AD in Malaysia. The aim of this study was to determine the proportion of CDF–, Der f 2– and Zen-1–specific reactive sera among dogs diagnosed with AD in Malaysia using an enzyme-linked immunosorbent assay (ELISA). Serum samples were collected from dogs diagnosed with AD from several veterinary clinics in Malaysia. The canine case records were retrieved and information on signalment, dermatological and non-dermatological histories, clinical presentation, food allergies, and exclusion of ectoparasitic, microbial and fungal skin infections were obtained through a survey form. All serum samples were evaluated to quantify the CDF–, Der f 2– and Zen-1–specific immunoglobulin E (IgE) levels. A total of 24.6%, 48.4% and 29.8% of dogs diagnosed with AD were positive for CDF–, Der f 2– and Zen-1–specific IgE, respectively. These results suggest that CDF–, Der f 2– and Zen-1 are important allergens that can contribute to AD in dogs in Malaysia, and serological testing can be performed to provide additional treatment options involving specific immunotherapies.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">CDF</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Zen-1</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Atopic dermatitis</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">IgE</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Dogs</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Dust mites</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Der f 2</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Selvarajah, Gayathri Thevi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ajat, Mokrish</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Suzuki, Rieko</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tsukui, Toshihiro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="t">Mo1377 Safety and Effectiveness of Colorectal Endoscopic Submucosal Dissection in Elderly Patients: Clinical Outcomes Including Long-Term Follow-up</subfield><subfield code="d">2012</subfield><subfield code="d">an international journal dealing with the study of veterinary immunology and immunopathology as applied to domestic animals, laboratory animals and other species that are useful to man</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011273445</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:212</subfield><subfield code="g">year:2019</subfield><subfield code="g">pages:43-49</subfield><subfield code="g">extent:7</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.vetimm.2019.05.002</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">51.00</subfield><subfield code="j">Werkstoffkunde: Allgemeines</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">212</subfield><subfield code="j">2019</subfield><subfield code="h">43-49</subfield><subfield code="g">7</subfield></datafield></record></collection>
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