Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases
Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the p...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Charney, Alexander W. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Umfang: |
10 |
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| Übergeordnetes Werk: |
Enthalten in: Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells - Xu, Qi ELSEVIER, 2016, a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry, Amsterdam [u.a.] |
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| Übergeordnetes Werk: |
volume:86 ; year:2019 ; number:2 ; day:15 ; month:07 ; pages:110-119 ; extent:10 |
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| DOI / URN: |
10.1016/j.biopsych.2018.12.009 |
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| 520 | |a Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. | ||
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10.1016/j.biopsych.2018.12.009 doi GBV00000000000673.pica (DE-627)ELV047260165 (ELSEVIER)S0006-3223(18)32087-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.40 bkl Charney, Alexander W. verfasserin aut Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases 2019 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. Polygenic risk score Elsevier Copy number variant Elsevier Schizophrenia Elsevier Bipolar disorder Elsevier Genetics Elsevier Rare variant burden Elsevier Stahl, Eli A. oth Green, Elaine K. oth Chen, Chia-Yen oth Moran, Jennifer L. oth Chambert, Kimberly oth Belliveau, Richard A. oth Forty, Liz oth Gordon-Smith, Katherine oth Lee, Phil H. oth Bromet, Evelyn J. oth Buckley, Peter F. oth Escamilla, Michael A. oth Fanous, Ayman H. oth Fochtmann, Laura J. oth Lehrer, Douglas S. oth Malaspina, Dolores oth Marder, Stephen R. oth Morley, Christopher P. oth Nicolini, Humberto oth Perkins, Diana O. oth Rakofsky, Jeffrey J. oth Rapaport, Mark H. oth Medeiros, Helena oth Sobell, Janet L. oth Backlund, Lena oth Bergen, Sarah E. oth Juréus, Anders oth Schalling, Martin oth Lichtenstein, Paul oth Knowles, James A. oth Burdick, Katherine E. oth Jones, Ian oth Jones, Lisa A. oth Hultman, Christina M. oth Perlis, Roy oth Purcell, Shaun M. oth McCarroll, Steven A. oth Pato, Carlos N. oth Pato, Michele T. oth Di Florio, Ariana oth Craddock, Nick oth Landén, Mikael oth Smoller, Jordan W. oth Ruderfer, Douglas M. oth Sklar, Pamela oth Enthalten in Elsevier Science Xu, Qi ELSEVIER Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells 2016 a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry Amsterdam [u.a.] (DE-627)ELV01006897X volume:86 year:2019 number:2 day:15 month:07 pages:110-119 extent:10 https://doi.org/10.1016/j.biopsych.2018.12.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 86 2019 2 15 0715 110-119 10 |
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10.1016/j.biopsych.2018.12.009 doi GBV00000000000673.pica (DE-627)ELV047260165 (ELSEVIER)S0006-3223(18)32087-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.40 bkl Charney, Alexander W. verfasserin aut Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases 2019 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. Polygenic risk score Elsevier Copy number variant Elsevier Schizophrenia Elsevier Bipolar disorder Elsevier Genetics Elsevier Rare variant burden Elsevier Stahl, Eli A. oth Green, Elaine K. oth Chen, Chia-Yen oth Moran, Jennifer L. oth Chambert, Kimberly oth Belliveau, Richard A. oth Forty, Liz oth Gordon-Smith, Katherine oth Lee, Phil H. oth Bromet, Evelyn J. oth Buckley, Peter F. oth Escamilla, Michael A. oth Fanous, Ayman H. oth Fochtmann, Laura J. oth Lehrer, Douglas S. oth Malaspina, Dolores oth Marder, Stephen R. oth Morley, Christopher P. oth Nicolini, Humberto oth Perkins, Diana O. oth Rakofsky, Jeffrey J. oth Rapaport, Mark H. oth Medeiros, Helena oth Sobell, Janet L. oth Backlund, Lena oth Bergen, Sarah E. oth Juréus, Anders oth Schalling, Martin oth Lichtenstein, Paul oth Knowles, James A. oth Burdick, Katherine E. oth Jones, Ian oth Jones, Lisa A. oth Hultman, Christina M. oth Perlis, Roy oth Purcell, Shaun M. oth McCarroll, Steven A. oth Pato, Carlos N. oth Pato, Michele T. oth Di Florio, Ariana oth Craddock, Nick oth Landén, Mikael oth Smoller, Jordan W. oth Ruderfer, Douglas M. oth Sklar, Pamela oth Enthalten in Elsevier Science Xu, Qi ELSEVIER Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells 2016 a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry Amsterdam [u.a.] (DE-627)ELV01006897X volume:86 year:2019 number:2 day:15 month:07 pages:110-119 extent:10 https://doi.org/10.1016/j.biopsych.2018.12.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 86 2019 2 15 0715 110-119 10 |
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10.1016/j.biopsych.2018.12.009 doi GBV00000000000673.pica (DE-627)ELV047260165 (ELSEVIER)S0006-3223(18)32087-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.40 bkl Charney, Alexander W. verfasserin aut Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases 2019 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. Polygenic risk score Elsevier Copy number variant Elsevier Schizophrenia Elsevier Bipolar disorder Elsevier Genetics Elsevier Rare variant burden Elsevier Stahl, Eli A. oth Green, Elaine K. oth Chen, Chia-Yen oth Moran, Jennifer L. oth Chambert, Kimberly oth Belliveau, Richard A. oth Forty, Liz oth Gordon-Smith, Katherine oth Lee, Phil H. oth Bromet, Evelyn J. oth Buckley, Peter F. oth Escamilla, Michael A. oth Fanous, Ayman H. oth Fochtmann, Laura J. oth Lehrer, Douglas S. oth Malaspina, Dolores oth Marder, Stephen R. oth Morley, Christopher P. oth Nicolini, Humberto oth Perkins, Diana O. oth Rakofsky, Jeffrey J. oth Rapaport, Mark H. oth Medeiros, Helena oth Sobell, Janet L. oth Backlund, Lena oth Bergen, Sarah E. oth Juréus, Anders oth Schalling, Martin oth Lichtenstein, Paul oth Knowles, James A. oth Burdick, Katherine E. oth Jones, Ian oth Jones, Lisa A. oth Hultman, Christina M. oth Perlis, Roy oth Purcell, Shaun M. oth McCarroll, Steven A. oth Pato, Carlos N. oth Pato, Michele T. oth Di Florio, Ariana oth Craddock, Nick oth Landén, Mikael oth Smoller, Jordan W. oth Ruderfer, Douglas M. oth Sklar, Pamela oth Enthalten in Elsevier Science Xu, Qi ELSEVIER Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells 2016 a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry Amsterdam [u.a.] (DE-627)ELV01006897X volume:86 year:2019 number:2 day:15 month:07 pages:110-119 extent:10 https://doi.org/10.1016/j.biopsych.2018.12.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 86 2019 2 15 0715 110-119 10 |
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10.1016/j.biopsych.2018.12.009 doi GBV00000000000673.pica (DE-627)ELV047260165 (ELSEVIER)S0006-3223(18)32087-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.40 bkl Charney, Alexander W. verfasserin aut Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases 2019 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. Polygenic risk score Elsevier Copy number variant Elsevier Schizophrenia Elsevier Bipolar disorder Elsevier Genetics Elsevier Rare variant burden Elsevier Stahl, Eli A. oth Green, Elaine K. oth Chen, Chia-Yen oth Moran, Jennifer L. oth Chambert, Kimberly oth Belliveau, Richard A. oth Forty, Liz oth Gordon-Smith, Katherine oth Lee, Phil H. oth Bromet, Evelyn J. oth Buckley, Peter F. oth Escamilla, Michael A. oth Fanous, Ayman H. oth Fochtmann, Laura J. oth Lehrer, Douglas S. oth Malaspina, Dolores oth Marder, Stephen R. oth Morley, Christopher P. oth Nicolini, Humberto oth Perkins, Diana O. oth Rakofsky, Jeffrey J. oth Rapaport, Mark H. oth Medeiros, Helena oth Sobell, Janet L. oth Backlund, Lena oth Bergen, Sarah E. oth Juréus, Anders oth Schalling, Martin oth Lichtenstein, Paul oth Knowles, James A. oth Burdick, Katherine E. oth Jones, Ian oth Jones, Lisa A. oth Hultman, Christina M. oth Perlis, Roy oth Purcell, Shaun M. oth McCarroll, Steven A. oth Pato, Carlos N. oth Pato, Michele T. oth Di Florio, Ariana oth Craddock, Nick oth Landén, Mikael oth Smoller, Jordan W. oth Ruderfer, Douglas M. oth Sklar, Pamela oth Enthalten in Elsevier Science Xu, Qi ELSEVIER Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells 2016 a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry Amsterdam [u.a.] (DE-627)ELV01006897X volume:86 year:2019 number:2 day:15 month:07 pages:110-119 extent:10 https://doi.org/10.1016/j.biopsych.2018.12.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 86 2019 2 15 0715 110-119 10 |
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10.1016/j.biopsych.2018.12.009 doi GBV00000000000673.pica (DE-627)ELV047260165 (ELSEVIER)S0006-3223(18)32087-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.40 bkl Charney, Alexander W. verfasserin aut Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases 2019 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. Polygenic risk score Elsevier Copy number variant Elsevier Schizophrenia Elsevier Bipolar disorder Elsevier Genetics Elsevier Rare variant burden Elsevier Stahl, Eli A. oth Green, Elaine K. oth Chen, Chia-Yen oth Moran, Jennifer L. oth Chambert, Kimberly oth Belliveau, Richard A. oth Forty, Liz oth Gordon-Smith, Katherine oth Lee, Phil H. oth Bromet, Evelyn J. oth Buckley, Peter F. oth Escamilla, Michael A. oth Fanous, Ayman H. oth Fochtmann, Laura J. oth Lehrer, Douglas S. oth Malaspina, Dolores oth Marder, Stephen R. oth Morley, Christopher P. oth Nicolini, Humberto oth Perkins, Diana O. oth Rakofsky, Jeffrey J. oth Rapaport, Mark H. oth Medeiros, Helena oth Sobell, Janet L. oth Backlund, Lena oth Bergen, Sarah E. oth Juréus, Anders oth Schalling, Martin oth Lichtenstein, Paul oth Knowles, James A. oth Burdick, Katherine E. oth Jones, Ian oth Jones, Lisa A. oth Hultman, Christina M. oth Perlis, Roy oth Purcell, Shaun M. oth McCarroll, Steven A. oth Pato, Carlos N. oth Pato, Michele T. oth Di Florio, Ariana oth Craddock, Nick oth Landén, Mikael oth Smoller, Jordan W. oth Ruderfer, Douglas M. oth Sklar, Pamela oth Enthalten in Elsevier Science Xu, Qi ELSEVIER Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells 2016 a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry Amsterdam [u.a.] (DE-627)ELV01006897X volume:86 year:2019 number:2 day:15 month:07 pages:110-119 extent:10 https://doi.org/10.1016/j.biopsych.2018.12.009 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA SSG-OPC-PHA 44.40 Pharmazie Pharmazeutika VZ AR 86 2019 2 15 0715 110-119 10 |
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Enthalten in Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells Amsterdam [u.a.] volume:86 year:2019 number:2 day:15 month:07 pages:110-119 extent:10 |
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Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells |
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Charney, Alexander W. @@aut@@ Stahl, Eli A. @@oth@@ Green, Elaine K. @@oth@@ Chen, Chia-Yen @@oth@@ Moran, Jennifer L. @@oth@@ Chambert, Kimberly @@oth@@ Belliveau, Richard A. @@oth@@ Forty, Liz @@oth@@ Gordon-Smith, Katherine @@oth@@ Lee, Phil H. @@oth@@ Bromet, Evelyn J. @@oth@@ Buckley, Peter F. @@oth@@ Escamilla, Michael A. @@oth@@ Fanous, Ayman H. @@oth@@ Fochtmann, Laura J. @@oth@@ Lehrer, Douglas S. @@oth@@ Malaspina, Dolores @@oth@@ Marder, Stephen R. @@oth@@ Morley, Christopher P. @@oth@@ Nicolini, Humberto @@oth@@ Perkins, Diana O. @@oth@@ Rakofsky, Jeffrey J. @@oth@@ Rapaport, Mark H. @@oth@@ Medeiros, Helena @@oth@@ Sobell, Janet L. @@oth@@ Backlund, Lena @@oth@@ Bergen, Sarah E. @@oth@@ Juréus, Anders @@oth@@ Schalling, Martin @@oth@@ Lichtenstein, Paul @@oth@@ Knowles, James A. @@oth@@ Burdick, Katherine E. @@oth@@ Jones, Ian @@oth@@ Jones, Lisa A. @@oth@@ Hultman, Christina M. @@oth@@ Perlis, Roy @@oth@@ Purcell, Shaun M. @@oth@@ McCarroll, Steven A. @@oth@@ Pato, Carlos N. @@oth@@ Pato, Michele T. @@oth@@ Di Florio, Ariana @@oth@@ Craddock, Nick @@oth@@ Landén, Mikael @@oth@@ Smoller, Jordan W. @@oth@@ Ruderfer, Douglas M. @@oth@@ Sklar, Pamela @@oth@@ |
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contribution of rare copy number variants to bipolar disorder risk is limited to schizoaffective cases |
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Contribution of Rare Copy Number Variants to Bipolar Disorder Risk Is Limited to Schizoaffective Cases |
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Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. |
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Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. |
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Genetic risk for bipolar disorder (BD) is conferred through many common alleles, while a role for rare copy number variants (CNVs) is less clear. Subtypes of BD including schizoaffective disorder bipolar type (SAB), bipolar I disorder (BD I), and bipolar II disorder (BD II) differ according to the prominence and timing of psychosis, mania, and depression. The genetic factors contributing to the combination of symptoms among these subtypes are poorly understood. |
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