Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes
Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified m...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Ismail, Nur Amajeida [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019transfer abstract |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial - Li, Chenglong ELSEVIER, 2019, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:897 ; year:2019 ; day:1 ; month:10 ; pages:42-49 ; extent:8 |
| Links: |
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| DOI / URN: |
10.1016/j.jorganchem.2019.06.024 |
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| 520 | |a Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. | ||
| 520 | |a Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. | ||
| 650 | 7 | |a Acridine |2 Elsevier | |
| 650 | 7 | |a Platinum |2 Elsevier | |
| 650 | 7 | |a Anticancer |2 Elsevier | |
| 700 | 1 | |a Salman, Abbas Abdulameer |4 oth | |
| 700 | 1 | |a Mohd Yusof, Mohd Sukeri |4 oth | |
| 700 | 1 | |a Che Soh, Siti Kamilah |4 oth | |
| 700 | 1 | |a Kadir Pahirulzaman, Khomaizon Abdul |4 oth | |
| 700 | 1 | |a Ali, Hapipah Mohd |4 oth | |
| 700 | 1 | |a Sarip, Rozie |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Li, Chenglong ELSEVIER |t The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial |d 2019 |g New York, NY [u.a.] |w (DE-627)ELV002971518 |
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10.1016/j.jorganchem.2019.06.024 doi GBV00000000000698.pica (DE-627)ELV047420820 (ELSEVIER)S0022-328X(19)30263-3 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl 44.66 bkl Ismail, Nur Amajeida verfasserin aut Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes 2019transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Acridine Elsevier Platinum Elsevier Anticancer Elsevier Salman, Abbas Abdulameer oth Mohd Yusof, Mohd Sukeri oth Che Soh, Siti Kamilah oth Kadir Pahirulzaman, Khomaizon Abdul oth Ali, Hapipah Mohd oth Sarip, Rozie oth Enthalten in Elsevier Li, Chenglong ELSEVIER The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial 2019 New York, NY [u.a.] (DE-627)ELV002971518 volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 https://doi.org/10.1016/j.jorganchem.2019.06.024 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ 44.66 Anästhesiologie VZ AR 897 2019 1 1001 42-49 8 |
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10.1016/j.jorganchem.2019.06.024 doi GBV00000000000698.pica (DE-627)ELV047420820 (ELSEVIER)S0022-328X(19)30263-3 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl 44.66 bkl Ismail, Nur Amajeida verfasserin aut Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes 2019transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Acridine Elsevier Platinum Elsevier Anticancer Elsevier Salman, Abbas Abdulameer oth Mohd Yusof, Mohd Sukeri oth Che Soh, Siti Kamilah oth Kadir Pahirulzaman, Khomaizon Abdul oth Ali, Hapipah Mohd oth Sarip, Rozie oth Enthalten in Elsevier Li, Chenglong ELSEVIER The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial 2019 New York, NY [u.a.] (DE-627)ELV002971518 volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 https://doi.org/10.1016/j.jorganchem.2019.06.024 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ 44.66 Anästhesiologie VZ AR 897 2019 1 1001 42-49 8 |
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10.1016/j.jorganchem.2019.06.024 doi GBV00000000000698.pica (DE-627)ELV047420820 (ELSEVIER)S0022-328X(19)30263-3 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl 44.66 bkl Ismail, Nur Amajeida verfasserin aut Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes 2019transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Acridine Elsevier Platinum Elsevier Anticancer Elsevier Salman, Abbas Abdulameer oth Mohd Yusof, Mohd Sukeri oth Che Soh, Siti Kamilah oth Kadir Pahirulzaman, Khomaizon Abdul oth Ali, Hapipah Mohd oth Sarip, Rozie oth Enthalten in Elsevier Li, Chenglong ELSEVIER The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial 2019 New York, NY [u.a.] (DE-627)ELV002971518 volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 https://doi.org/10.1016/j.jorganchem.2019.06.024 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ 44.66 Anästhesiologie VZ AR 897 2019 1 1001 42-49 8 |
| allfieldsGer |
10.1016/j.jorganchem.2019.06.024 doi GBV00000000000698.pica (DE-627)ELV047420820 (ELSEVIER)S0022-328X(19)30263-3 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl 44.66 bkl Ismail, Nur Amajeida verfasserin aut Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes 2019transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Acridine Elsevier Platinum Elsevier Anticancer Elsevier Salman, Abbas Abdulameer oth Mohd Yusof, Mohd Sukeri oth Che Soh, Siti Kamilah oth Kadir Pahirulzaman, Khomaizon Abdul oth Ali, Hapipah Mohd oth Sarip, Rozie oth Enthalten in Elsevier Li, Chenglong ELSEVIER The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial 2019 New York, NY [u.a.] (DE-627)ELV002971518 volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 https://doi.org/10.1016/j.jorganchem.2019.06.024 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ 44.66 Anästhesiologie VZ AR 897 2019 1 1001 42-49 8 |
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10.1016/j.jorganchem.2019.06.024 doi GBV00000000000698.pica (DE-627)ELV047420820 (ELSEVIER)S0022-328X(19)30263-3 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl 44.66 bkl Ismail, Nur Amajeida verfasserin aut Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes 2019transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. Acridine Elsevier Platinum Elsevier Anticancer Elsevier Salman, Abbas Abdulameer oth Mohd Yusof, Mohd Sukeri oth Che Soh, Siti Kamilah oth Kadir Pahirulzaman, Khomaizon Abdul oth Ali, Hapipah Mohd oth Sarip, Rozie oth Enthalten in Elsevier Li, Chenglong ELSEVIER The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial 2019 New York, NY [u.a.] (DE-627)ELV002971518 volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 https://doi.org/10.1016/j.jorganchem.2019.06.024 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ 44.66 Anästhesiologie VZ AR 897 2019 1 1001 42-49 8 |
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Enthalten in The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial New York, NY [u.a.] volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 |
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Enthalten in The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial New York, NY [u.a.] volume:897 year:2019 day:1 month:10 pages:42-49 extent:8 |
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The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Postcardiotomy Patients with Cardiogenic Shock: A Pilot Randomized Controlled Trial |
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Ismail, Nur Amajeida @@aut@@ Salman, Abbas Abdulameer @@oth@@ Mohd Yusof, Mohd Sukeri @@oth@@ Che Soh, Siti Kamilah @@oth@@ Kadir Pahirulzaman, Khomaizon Abdul @@oth@@ Ali, Hapipah Mohd @@oth@@ Sarip, Rozie @@oth@@ |
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synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(ii) organometallic complexes |
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Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes |
| abstract |
Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. |
| abstractGer |
Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. |
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Two new platinum(II) complexes incorporating acridine ligands with aniline moieties were successfully synthesised and characterised. The acridine-based ligands were synthesised by means of Ullmann's condensation. The reaction of cis-[PtCl2(DMSO)2] with the aforementioned ligand in a specified mol ratio gives 9-phenylaminoacridine cis-dichloro(dimethylsulfoxide)-platinum(II), 2a, and bis-[N-(3,5-dimethoxyphenyl) acridin-9-amine)]chloro platinum(II), 2b. Apparently, both complexes were slightly planar and in discrete asymmetrical units. Cytotoxicity and antineoplastic activity evaluations were conducted using WRL-68, MCF-7, HT-29, and HL60 cell lines. The novel complexes exhibited potent activity towards the cell lines. Concurrently, the MTT cytotoxicity assay revealed that all complexes significantly inhibited the proliferation of MCF-7 and HL60 cells. |
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Synthesis, cytotoxicity and antineoplastic activities of novel acridine-based platinum(II) organometallic complexes |
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