NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2–3, randomised, controlled trial
Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiother...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Bonvalot, Sylvie [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Umfang: |
12 |
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| Übergeordnetes Werk: |
Enthalten in: My - Citovsky, Vitaly ELSEVIER, 2019, London |
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| Übergeordnetes Werk: |
volume:20 ; year:2019 ; number:8 ; pages:1148-1159 ; extent:12 |
| Links: |
|---|
| DOI / URN: |
10.1016/S1470-2045(19)30326-2 |
|---|
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| 520 | |a Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. | ||
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| 700 | 1 | |a Mervoyer, Augustin |4 oth | |
| 700 | 1 | |a Rastrelli, Marco |4 oth | |
| 700 | 1 | |a Moreno, Victor |4 oth | |
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| 700 | 1 | |a Helfre, Sylvie |4 oth | |
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10.1016/S1470-2045(19)30326-2 doi GBV00000000000765.pica (DE-627)ELV047451572 (ELSEVIER)S1470-2045(19)30326-2 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Bonvalot, Sylvie verfasserin aut NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2–3, randomised, controlled trial 2019 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. Rutkowski, Piotr L oth Thariat, Juliette oth Carrère, Sébastien oth Ducassou, Anne oth Sunyach, Marie-Pierre oth Agoston, Peter oth Hong, Angela oth Mervoyer, Augustin oth Rastrelli, Marco oth Moreno, Victor oth Li, Rubi K oth Tiangco, Béatrice oth Herraez, Antonio Casado oth Gronchi, Alessandro oth Mangel, László oth Sy-Ortin, Teresa oth Hohenberger, Peter oth de Baère, Thierry oth Le Cesne, Axel oth Helfre, Sylvie oth Saada-Bouzid, Esma oth Borkowska, Aneta oth Anghel, Rodica oth Co, Ann oth Gebhart, Michael oth Kantor, Guy oth Montero, Angel oth Loong, Herbert H oth Vergés, Ramona oth Lapeire, Lore oth Dema, Sorin oth Kacso, Gabriel oth Austen, Lyn oth Moureau-Zabotto, Laurence oth Servois, Vincent oth Wardelmann, Eva oth Terrier, Philippe oth Lazar, Alexander J oth Bovée, Judith V M G oth Le Péchoux, Cécile oth Papai, Zsusanna oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:20 year:2019 number:8 pages:1148-1159 extent:12 https://doi.org/10.1016/S1470-2045(19)30326-2 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 20 2019 8 1148-1159 12 |
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10.1016/S1470-2045(19)30326-2 doi GBV00000000000765.pica (DE-627)ELV047451572 (ELSEVIER)S1470-2045(19)30326-2 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Bonvalot, Sylvie verfasserin aut NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2–3, randomised, controlled trial 2019 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. Rutkowski, Piotr L oth Thariat, Juliette oth Carrère, Sébastien oth Ducassou, Anne oth Sunyach, Marie-Pierre oth Agoston, Peter oth Hong, Angela oth Mervoyer, Augustin oth Rastrelli, Marco oth Moreno, Victor oth Li, Rubi K oth Tiangco, Béatrice oth Herraez, Antonio Casado oth Gronchi, Alessandro oth Mangel, László oth Sy-Ortin, Teresa oth Hohenberger, Peter oth de Baère, Thierry oth Le Cesne, Axel oth Helfre, Sylvie oth Saada-Bouzid, Esma oth Borkowska, Aneta oth Anghel, Rodica oth Co, Ann oth Gebhart, Michael oth Kantor, Guy oth Montero, Angel oth Loong, Herbert H oth Vergés, Ramona oth Lapeire, Lore oth Dema, Sorin oth Kacso, Gabriel oth Austen, Lyn oth Moureau-Zabotto, Laurence oth Servois, Vincent oth Wardelmann, Eva oth Terrier, Philippe oth Lazar, Alexander J oth Bovée, Judith V M G oth Le Péchoux, Cécile oth Papai, Zsusanna oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:20 year:2019 number:8 pages:1148-1159 extent:12 https://doi.org/10.1016/S1470-2045(19)30326-2 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 20 2019 8 1148-1159 12 |
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10.1016/S1470-2045(19)30326-2 doi GBV00000000000765.pica (DE-627)ELV047451572 (ELSEVIER)S1470-2045(19)30326-2 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Bonvalot, Sylvie verfasserin aut NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2–3, randomised, controlled trial 2019 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. Rutkowski, Piotr L oth Thariat, Juliette oth Carrère, Sébastien oth Ducassou, Anne oth Sunyach, Marie-Pierre oth Agoston, Peter oth Hong, Angela oth Mervoyer, Augustin oth Rastrelli, Marco oth Moreno, Victor oth Li, Rubi K oth Tiangco, Béatrice oth Herraez, Antonio Casado oth Gronchi, Alessandro oth Mangel, László oth Sy-Ortin, Teresa oth Hohenberger, Peter oth de Baère, Thierry oth Le Cesne, Axel oth Helfre, Sylvie oth Saada-Bouzid, Esma oth Borkowska, Aneta oth Anghel, Rodica oth Co, Ann oth Gebhart, Michael oth Kantor, Guy oth Montero, Angel oth Loong, Herbert H oth Vergés, Ramona oth Lapeire, Lore oth Dema, Sorin oth Kacso, Gabriel oth Austen, Lyn oth Moureau-Zabotto, Laurence oth Servois, Vincent oth Wardelmann, Eva oth Terrier, Philippe oth Lazar, Alexander J oth Bovée, Judith V M G oth Le Péchoux, Cécile oth Papai, Zsusanna oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:20 year:2019 number:8 pages:1148-1159 extent:12 https://doi.org/10.1016/S1470-2045(19)30326-2 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 20 2019 8 1148-1159 12 |
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10.1016/S1470-2045(19)30326-2 doi GBV00000000000765.pica (DE-627)ELV047451572 (ELSEVIER)S1470-2045(19)30326-2 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Bonvalot, Sylvie verfasserin aut NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2–3, randomised, controlled trial 2019 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. Rutkowski, Piotr L oth Thariat, Juliette oth Carrère, Sébastien oth Ducassou, Anne oth Sunyach, Marie-Pierre oth Agoston, Peter oth Hong, Angela oth Mervoyer, Augustin oth Rastrelli, Marco oth Moreno, Victor oth Li, Rubi K oth Tiangco, Béatrice oth Herraez, Antonio Casado oth Gronchi, Alessandro oth Mangel, László oth Sy-Ortin, Teresa oth Hohenberger, Peter oth de Baère, Thierry oth Le Cesne, Axel oth Helfre, Sylvie oth Saada-Bouzid, Esma oth Borkowska, Aneta oth Anghel, Rodica oth Co, Ann oth Gebhart, Michael oth Kantor, Guy oth Montero, Angel oth Loong, Herbert H oth Vergés, Ramona oth Lapeire, Lore oth Dema, Sorin oth Kacso, Gabriel oth Austen, Lyn oth Moureau-Zabotto, Laurence oth Servois, Vincent oth Wardelmann, Eva oth Terrier, Philippe oth Lazar, Alexander J oth Bovée, Judith V M G oth Le Péchoux, Cécile oth Papai, Zsusanna oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:20 year:2019 number:8 pages:1148-1159 extent:12 https://doi.org/10.1016/S1470-2045(19)30326-2 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 20 2019 8 1148-1159 12 |
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Bonvalot, Sylvie @@aut@@ Rutkowski, Piotr L @@oth@@ Thariat, Juliette @@oth@@ Carrère, Sébastien @@oth@@ Ducassou, Anne @@oth@@ Sunyach, Marie-Pierre @@oth@@ Agoston, Peter @@oth@@ Hong, Angela @@oth@@ Mervoyer, Augustin @@oth@@ Rastrelli, Marco @@oth@@ Moreno, Victor @@oth@@ Li, Rubi K @@oth@@ Tiangco, Béatrice @@oth@@ Herraez, Antonio Casado @@oth@@ Gronchi, Alessandro @@oth@@ Mangel, László @@oth@@ Sy-Ortin, Teresa @@oth@@ Hohenberger, Peter @@oth@@ de Baère, Thierry @@oth@@ Le Cesne, Axel @@oth@@ Helfre, Sylvie @@oth@@ Saada-Bouzid, Esma @@oth@@ Borkowska, Aneta @@oth@@ Anghel, Rodica @@oth@@ Co, Ann @@oth@@ Gebhart, Michael @@oth@@ Kantor, Guy @@oth@@ Montero, Angel @@oth@@ Loong, Herbert H @@oth@@ Vergés, Ramona @@oth@@ Lapeire, Lore @@oth@@ Dema, Sorin @@oth@@ Kacso, Gabriel @@oth@@ Austen, Lyn @@oth@@ Moureau-Zabotto, Laurence @@oth@@ Servois, Vincent @@oth@@ Wardelmann, Eva @@oth@@ Terrier, Philippe @@oth@@ Lazar, Alexander J @@oth@@ Bovée, Judith V M G @@oth@@ Le Péchoux, Cécile @@oth@@ Papai, Zsusanna @@oth@@ |
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Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. |
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Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. |
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Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a few patients receiving radiotherapy. This phase 2–3 trial evaluated the safety and efficacy of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma. |
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