Estimated impact of human papillomavirus vaccines on infection burden: The effect of structural assumptions
• We simulate RCTs using models that include/exclude reactivation of latent HPV infection. • RCTs estimate a difference in HPV vaccine effectiveness for more and less sexually naïve subsets. • Models without reactivation of latent infection cannot match this difference. • HPV models without reactiva...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
van Schalkwyk, Cari [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
|---|
| Umfang: |
6 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement - Li, Yaoyao ELSEVIER, 2022, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:37 ; year:2019 ; number:36 ; day:23 ; month:08 ; pages:5460-5465 ; extent:6 |
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| DOI / URN: |
10.1016/j.vaccine.2019.06.013 |
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• We simulate RCTs using models that include/exclude reactivation of latent HPV infection. • RCTs estimate a difference in HPV vaccine effectiveness for more and less sexually naïve subsets. • Models without reactivation of latent infection cannot match this difference. • HPV models without reactivation of latent infection may overestimate vaccine impact. |
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