Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming
Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Bax, Monique [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2019transfer abstract |
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| Übergeordnetes Werk: |
Enthalten in: Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study - Hamood, Rola ELSEVIER, 2018, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:40 ; year:2019 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.scr.2019.101530 |
|---|
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ELV04819090X |
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| 520 | |a Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. | ||
| 520 | |a Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. | ||
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10.1016/j.scr.2019.101530 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001483.pica (DE-627)ELV04819090X (ELSEVIER)S1873-5061(19)30160-6 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Bax, Monique verfasserin aut Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Balez, Rachelle oth Muñoz, Sonia Sanz oth Do-Ha, Dzung oth Stevens, Claire H. oth Berg, Tracey oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Nicholson, Garth oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:40 year:2019 pages:0 https://doi.org/10.1016/j.scr.2019.101530 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 40 2019 0 |
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10.1016/j.scr.2019.101530 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001483.pica (DE-627)ELV04819090X (ELSEVIER)S1873-5061(19)30160-6 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Bax, Monique verfasserin aut Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Balez, Rachelle oth Muñoz, Sonia Sanz oth Do-Ha, Dzung oth Stevens, Claire H. oth Berg, Tracey oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Nicholson, Garth oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:40 year:2019 pages:0 https://doi.org/10.1016/j.scr.2019.101530 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 40 2019 0 |
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10.1016/j.scr.2019.101530 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001483.pica (DE-627)ELV04819090X (ELSEVIER)S1873-5061(19)30160-6 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Bax, Monique verfasserin aut Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Balez, Rachelle oth Muñoz, Sonia Sanz oth Do-Ha, Dzung oth Stevens, Claire H. oth Berg, Tracey oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Nicholson, Garth oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:40 year:2019 pages:0 https://doi.org/10.1016/j.scr.2019.101530 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 40 2019 0 |
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10.1016/j.scr.2019.101530 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001483.pica (DE-627)ELV04819090X (ELSEVIER)S1873-5061(19)30160-6 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Bax, Monique verfasserin aut Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Balez, Rachelle oth Muñoz, Sonia Sanz oth Do-Ha, Dzung oth Stevens, Claire H. oth Berg, Tracey oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Nicholson, Garth oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:40 year:2019 pages:0 https://doi.org/10.1016/j.scr.2019.101530 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 40 2019 0 |
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10.1016/j.scr.2019.101530 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001483.pica (DE-627)ELV04819090X (ELSEVIER)S1873-5061(19)30160-6 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Bax, Monique verfasserin aut Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming 2019transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. Balez, Rachelle oth Muñoz, Sonia Sanz oth Do-Ha, Dzung oth Stevens, Claire H. oth Berg, Tracey oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Nicholson, Garth oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:40 year:2019 pages:0 https://doi.org/10.1016/j.scr.2019.101530 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 40 2019 0 |
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Enthalten in Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study Amsterdam [u.a.] volume:40 year:2019 pages:0 |
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Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming |
| ctrlnum |
(DE-627)ELV04819090X (ELSEVIER)S1873-5061(19)30160-6 |
| title_full |
Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming |
| author_sort |
Bax, Monique |
| journal |
Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
| journalStr |
Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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eng |
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false |
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600 - Technology |
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marc |
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2019 |
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Bax, Monique |
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40 |
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610 VZ 44.85 bkl |
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Elektronische Aufsätze |
| author-letter |
Bax, Monique |
| doi_str_mv |
10.1016/j.scr.2019.101530 |
| dewey-full |
610 |
| title_sort |
generation and characterization of a human induced pluripotent stem cell line uowi005-a from dermal fibroblasts derived from a ccnf s621g familial amyotrophic lateral sclerosis patient using mrna reprogramming |
| title_auth |
Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming |
| abstract |
Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. |
| abstractGer |
Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. |
| abstract_unstemmed |
Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNF S621G ), were reprogrammed using mRNA and microRNA-delivered OSKM factors to induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed pluripotent, expressing typical pluripotency markers and were capable of three germ layer differentiation. This is the first reported reprogramming of cells with a mutation in the cyclin F gene, and represents a novel resource for the study of amyotrophic lateral sclerosis. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| title_short |
Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNF S621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming |
| url |
https://doi.org/10.1016/j.scr.2019.101530 |
| remote_bool |
true |
| author2 |
Balez, Rachelle Muñoz, Sonia Sanz Do-Ha, Dzung Stevens, Claire H. Berg, Tracey Cabral-da-Silva, Mauricio C. Engel, Martin Nicholson, Garth Yang, Shu Blair, Ian P. Ooi, Lezanne |
| author2Str |
Balez, Rachelle Muñoz, Sonia Sanz Do-Ha, Dzung Stevens, Claire H. Berg, Tracey Cabral-da-Silva, Mauricio C. Engel, Martin Nicholson, Garth Yang, Shu Blair, Ian P. Ooi, Lezanne |
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| doi_str |
10.1016/j.scr.2019.101530 |
| up_date |
2024-07-06T18:10:58.079Z |
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