Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1

• Pre-mRNA for the DNA repair enzyme NEIL1 is edited by adenosine deaminase ADAR1. • The efficiencies of unedited (K242) and edited (K242R) NEIL1 were compared. • K242 was more efficient in excision of ThyGly and aflatoxin-induced FapyGua lesions. • K242R was more efficient in excision of FapyAde, F...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Minko, Irina G. [verfasserIn]

Vartanian, Vladimir L.

Tozaki, Naoto N.

Coskun, Erdem

Coskun, Sanem Hosbas

Jaruga, Pawel

Yeo, Jongchan

David, Sheila S.

Stone, Michael P.

Egli, Martin

Dizdaroglu, Miral

McCullough, Amanda K.

Lloyd, R. Stephen

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2020

Schlagwörter:

8-OH-Gua

Gh

FapyAde

ThyGly

HCC

AFB1

5-OH-MeHyd

FapyGua

5-OH-Cyt

8-OH-Ade

5-OH-Ura

5,6-diOH-Ura

GC-MS/MS

Sp

AFB1-FapyGua

Übergeordnetes Werk:

Enthalten in: Reply - Zhang, Lin ELSEVIER, 2022, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:85 ; year:2020 ; pages:0

Links:

Volltext

DOI / URN:

10.1016/j.dnarep.2019.102741

Katalog-ID:

ELV049003348

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