Roles of the matricellular protein Tenascin-C in T-lymphocyte trafficking and etiopathogenesis of Oral Lichen Planus
• Pathogonomic feature of oral lichen planus is a interphase T lymphocyte infiltrate. • Tenascin-C is a matricellular protein with key roles in cell trafficking. • Tenascin-C expression is increased in oral lichen planus in vivo. • Increased T lymphocytes migration to Tenascin C was noted in vitro....
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Mane, Deepa R. [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2020 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: A SNP genotype in the TGFBR1 gene is associated with earlier onset of colorectal cancer in males - Mahon, G. ELSEVIER, 2017, a multidisciplinary journal in oral research, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:110 ; year:2020 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.archoralbio.2019.104622 |
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Roles of the matricellular protein Tenascin-C in T-lymphocyte trafficking and etiopathogenesis of Oral Lichen Planus |
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• Pathogonomic feature of oral lichen planus is a interphase T lymphocyte infiltrate. • Tenascin-C is a matricellular protein with key roles in cell trafficking. • Tenascin-C expression is increased in oral lichen planus in vivo. • Increased T lymphocytes migration to Tenascin C was noted in vitro. • These observations provide insights into potential etiology and future therapies. |
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• Pathogonomic feature of oral lichen planus is a interphase T lymphocyte infiltrate. • Tenascin-C is a matricellular protein with key roles in cell trafficking. • Tenascin-C expression is increased in oral lichen planus in vivo. • Increased T lymphocytes migration to Tenascin C was noted in vitro. • These observations provide insights into potential etiology and future therapies. |
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• Pathogonomic feature of oral lichen planus is a interphase T lymphocyte infiltrate. • Tenascin-C is a matricellular protein with key roles in cell trafficking. • Tenascin-C expression is increased in oral lichen planus in vivo. • Increased T lymphocytes migration to Tenascin C was noted in vitro. • These observations provide insights into potential etiology and future therapies. |
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Roles of the matricellular protein Tenascin-C in T-lymphocyte trafficking and etiopathogenesis of Oral Lichen Planus |
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