Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz
Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunosti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Wang, Juan [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020transfer abstract |
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| Schlagwörter: |
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| Umfang: |
8 |
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| Übergeordnetes Werk: |
Enthalten in: Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor - Penchovsky, Robert ELSEVIER, 2019, structure, function and interactions, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:143 ; year:2020 ; day:15 ; month:01 ; pages:842-849 ; extent:8 |
| Links: |
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| DOI / URN: |
10.1016/j.ijbiomac.2019.09.145 |
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ELV049047841 |
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| 520 | |a Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. | ||
| 520 | |a Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. | ||
| 650 | 7 | |a Preliminary characterization |2 Elsevier | |
| 650 | 7 | |a Artemisia selengensis Turcz |2 Elsevier | |
| 650 | 7 | |a Antioxidant activity |2 Elsevier | |
| 650 | 7 | |a Polysaccharide |2 Elsevier | |
| 650 | 7 | |a Immunostimulatory activity |2 Elsevier | |
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| 700 | 1 | |a Lu, Zhaoxin |4 oth | |
| 700 | 1 | |a Lu, Fengxia |4 oth | |
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10.1016/j.ijbiomac.2019.09.145 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000872.pica (DE-627)ELV049047841 (ELSEVIER)S0141-8130(19)36741-8 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Wang, Juan verfasserin aut Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz 2020transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Preliminary characterization Elsevier Artemisia selengensis Turcz Elsevier Antioxidant activity Elsevier Polysaccharide Elsevier Immunostimulatory activity Elsevier Han, Jinzhi oth Lu, Zhaoxin oth Lu, Fengxia oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:143 year:2020 day:15 month:01 pages:842-849 extent:8 https://doi.org/10.1016/j.ijbiomac.2019.09.145 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 143 2020 15 0115 842-849 8 |
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10.1016/j.ijbiomac.2019.09.145 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000872.pica (DE-627)ELV049047841 (ELSEVIER)S0141-8130(19)36741-8 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Wang, Juan verfasserin aut Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz 2020transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Preliminary characterization Elsevier Artemisia selengensis Turcz Elsevier Antioxidant activity Elsevier Polysaccharide Elsevier Immunostimulatory activity Elsevier Han, Jinzhi oth Lu, Zhaoxin oth Lu, Fengxia oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:143 year:2020 day:15 month:01 pages:842-849 extent:8 https://doi.org/10.1016/j.ijbiomac.2019.09.145 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 143 2020 15 0115 842-849 8 |
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10.1016/j.ijbiomac.2019.09.145 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000872.pica (DE-627)ELV049047841 (ELSEVIER)S0141-8130(19)36741-8 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Wang, Juan verfasserin aut Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz 2020transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Preliminary characterization Elsevier Artemisia selengensis Turcz Elsevier Antioxidant activity Elsevier Polysaccharide Elsevier Immunostimulatory activity Elsevier Han, Jinzhi oth Lu, Zhaoxin oth Lu, Fengxia oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:143 year:2020 day:15 month:01 pages:842-849 extent:8 https://doi.org/10.1016/j.ijbiomac.2019.09.145 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 143 2020 15 0115 842-849 8 |
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10.1016/j.ijbiomac.2019.09.145 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000872.pica (DE-627)ELV049047841 (ELSEVIER)S0141-8130(19)36741-8 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Wang, Juan verfasserin aut Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz 2020transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Preliminary characterization Elsevier Artemisia selengensis Turcz Elsevier Antioxidant activity Elsevier Polysaccharide Elsevier Immunostimulatory activity Elsevier Han, Jinzhi oth Lu, Zhaoxin oth Lu, Fengxia oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:143 year:2020 day:15 month:01 pages:842-849 extent:8 https://doi.org/10.1016/j.ijbiomac.2019.09.145 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 143 2020 15 0115 842-849 8 |
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10.1016/j.ijbiomac.2019.09.145 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000872.pica (DE-627)ELV049047841 (ELSEVIER)S0141-8130(19)36741-8 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Wang, Juan verfasserin aut Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz 2020transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. Preliminary characterization Elsevier Artemisia selengensis Turcz Elsevier Antioxidant activity Elsevier Polysaccharide Elsevier Immunostimulatory activity Elsevier Han, Jinzhi oth Lu, Zhaoxin oth Lu, Fengxia oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:143 year:2020 day:15 month:01 pages:842-849 extent:8 https://doi.org/10.1016/j.ijbiomac.2019.09.145 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 143 2020 15 0115 842-849 8 |
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preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from artemisia selengensis turcz |
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Preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from Artemisia selengensis Turcz |
| abstract |
Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. |
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Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. |
| abstract_unstemmed |
Artemisia selengensis Turcz possesses various health-promoting functions. However, the available information regarding the structure and biological activity of polysaccharides from A. selengensis Turcz (APS) is still limited. In the present study, the preliminary structure, antioxidant and immunostimulatory activities of a polysaccharide fraction from APS (APS1) were investigated. Results of Fourier transform-infrared spectroscopy (FT-IR), gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) analyses showed that the main chain of APS1 was made up of T-α-D-Glcp-(1→, →4)-α-D-Glcp-(1 → and → 4)-α-D-Galp-(1 → residues). In addition, the moderate superoxide and ABTS radical scavenging activities and noticeable Fe2+ chelating activity of APS1 were observed. Furthermore, the administration of APS1 could significantly restore spleen and thymus indexes, increase the levels of serum hemolysin and lysozyme, and improve the liver function by remarkably preventing the elevation of MDA level and increasing the levels of catalase (CAT), total antioxidant capacity (T-AOC), superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in cyclophosphamide-treated mice. These results suggested that APS1 exhibits antioxidant and immunostimulatory activities with potential application in functional foods. |
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