The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007
Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcripti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Balez, Rachelle [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2020transfer abstract |
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| Übergeordnetes Werk: |
Enthalten in: Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study - Hamood, Rola ELSEVIER, 2018, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:42 ; year:2020 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1016/j.scr.2020.101701 |
|---|
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ELV049260944 |
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| 520 | |a Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. | ||
| 520 | |a Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. | ||
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| 700 | 1 | |a Stevens, Claire H. |4 oth | |
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10.1016/j.scr.2020.101701 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000968.pica (DE-627)ELV049260944 (ELSEVIER)S1873-5061(20)30003-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Balez, Rachelle verfasserin aut The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Berg, Tracey oth Bax, Monique oth Muñoz, Sonia Sanz oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Do-Ha, Dzung oth Stevens, Claire H. oth Rowe, Dominic oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:42 year:2020 pages:0 https://doi.org/10.1016/j.scr.2020.101701 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 42 2020 0 |
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10.1016/j.scr.2020.101701 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000968.pica (DE-627)ELV049260944 (ELSEVIER)S1873-5061(20)30003-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Balez, Rachelle verfasserin aut The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Berg, Tracey oth Bax, Monique oth Muñoz, Sonia Sanz oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Do-Ha, Dzung oth Stevens, Claire H. oth Rowe, Dominic oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:42 year:2020 pages:0 https://doi.org/10.1016/j.scr.2020.101701 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 42 2020 0 |
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10.1016/j.scr.2020.101701 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000968.pica (DE-627)ELV049260944 (ELSEVIER)S1873-5061(20)30003-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Balez, Rachelle verfasserin aut The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Berg, Tracey oth Bax, Monique oth Muñoz, Sonia Sanz oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Do-Ha, Dzung oth Stevens, Claire H. oth Rowe, Dominic oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:42 year:2020 pages:0 https://doi.org/10.1016/j.scr.2020.101701 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 42 2020 0 |
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10.1016/j.scr.2020.101701 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000968.pica (DE-627)ELV049260944 (ELSEVIER)S1873-5061(20)30003-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Balez, Rachelle verfasserin aut The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Berg, Tracey oth Bax, Monique oth Muñoz, Sonia Sanz oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Do-Ha, Dzung oth Stevens, Claire H. oth Rowe, Dominic oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:42 year:2020 pages:0 https://doi.org/10.1016/j.scr.2020.101701 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 42 2020 0 |
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10.1016/j.scr.2020.101701 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000968.pica (DE-627)ELV049260944 (ELSEVIER)S1873-5061(20)30003-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.85 bkl Balez, Rachelle verfasserin aut The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. Berg, Tracey oth Bax, Monique oth Muñoz, Sonia Sanz oth Cabral-da-Silva, Mauricio C. oth Engel, Martin oth Do-Ha, Dzung oth Stevens, Claire H. oth Rowe, Dominic oth Yang, Shu oth Blair, Ian P. oth Ooi, Lezanne oth Enthalten in Elsevier Hamood, Rola ELSEVIER Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study 2018 Amsterdam [u.a.] (DE-627)ELV001654470 volume:42 year:2020 pages:0 https://doi.org/10.1016/j.scr.2020.101701 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.85 Kardiologie Angiologie VZ AR 42 2020 0 |
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Enthalten in Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study Amsterdam [u.a.] volume:42 year:2020 pages:0 |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 |
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The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 |
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Balez, Rachelle |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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Risk of cardiovascular disease after radiotherapy in survivors of breast cancer: A case-cohort study |
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mrna-based reprogramming of fibroblasts from a sod1 e101g familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line uowi007 |
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The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 |
| abstract |
Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. |
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Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. |
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Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1 E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeated mRNA transfections for pluripotency transcription factors Oct4, Klf4, Sox2, c-Myc, Lin28 and Nanog. The iPSCs carried the SOD1 E101G genotype and had a normal karyotype, expressed expected pluripotency markers and were capable of in vitro differentiation into endodermal, mesodermal and ectodermal lineages. This iPSC line may be useful for investigating familial ALS resulting from a SOD1 E101G mutation. |
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The mRNA-based reprogramming of fibroblasts from a SOD1 E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007 |
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https://doi.org/10.1016/j.scr.2020.101701 |
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Berg, Tracey Bax, Monique Muñoz, Sonia Sanz Cabral-da-Silva, Mauricio C. Engel, Martin Do-Ha, Dzung Stevens, Claire H. Rowe, Dominic Yang, Shu Blair, Ian P. Ooi, Lezanne |
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Berg, Tracey Bax, Monique Muñoz, Sonia Sanz Cabral-da-Silva, Mauricio C. Engel, Martin Do-Ha, Dzung Stevens, Claire H. Rowe, Dominic Yang, Shu Blair, Ian P. Ooi, Lezanne |
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