An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion
For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precis...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Funayama, Tomoo [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2020transfer abstract |
|---|
| Schlagwörter: |
Targeted irradiation of cultured cells |
|---|
| Umfang: |
9 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Editorial Comment - Unwala, Darius J. ELSEVIER, 2013, a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:465 ; year:2020 ; day:15 ; month:02 ; pages:101-109 ; extent:9 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.nimb.2019.12.028 |
|---|
| Katalog-ID: |
ELV049340166 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV049340166 | ||
| 003 | DE-627 | ||
| 005 | 20230626024113.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 200518s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.nimb.2019.12.028 |2 doi | |
| 028 | 5 | 2 | |a /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica |
| 035 | |a (DE-627)ELV049340166 | ||
| 035 | |a (ELSEVIER)S0168-583X(19)30847-X | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q VZ |
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.85 |2 bkl | ||
| 100 | 1 | |a Funayama, Tomoo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| 264 | 1 | |c 2020transfer abstract | |
| 300 | |a 9 | ||
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. | ||
| 520 | |a For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. | ||
| 650 | 7 | |a Targeted irradiation of cultured cells |2 Elsevier | |
| 650 | 7 | |a High linear energy transfer |2 Elsevier | |
| 650 | 7 | |a Targeted irradiation of Caenorhabditis elegans |2 Elsevier | |
| 650 | 7 | |a Heavy-ion |2 Elsevier | |
| 650 | 7 | |a Microbeam |2 Elsevier | |
| 700 | 1 | |a Sakashita, Tetsuya |4 oth | |
| 700 | 1 | |a Suzuki, Michiyo |4 oth | |
| 700 | 1 | |a Yokota, Yuichiro |4 oth | |
| 700 | 1 | |a Miyawaki, Nobumasa |4 oth | |
| 700 | 1 | |a Kashiwagi, Hirotsugu |4 oth | |
| 700 | 1 | |a Satoh, Takahiro |4 oth | |
| 700 | 1 | |a Kurashima, Satoshi |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Unwala, Darius J. ELSEVIER |t Editorial Comment |d 2013 |d a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics |g Amsterdam [u.a.] |w (DE-627)ELV011304669 |
| 773 | 1 | 8 | |g volume:465 |g year:2020 |g day:15 |g month:02 |g pages:101-109 |g extent:9 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.nimb.2019.12.028 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a SSG-OLC-PHA | ||
| 912 | |a GBV_ILN_21 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_2001 | ||
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2007 | ||
| 936 | b | k | |a 44.85 |j Kardiologie |j Angiologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 465 |j 2020 |b 15 |c 0215 |h 101-109 |g 9 | ||
| author_variant |
t f tf |
|---|---|
| matchkey_str |
funayamatomoosakashitatetsuyasuzukimichi:2020----:nraitodvcfrilgclagtuigouemcoemocc |
| hierarchy_sort_str |
2020transfer abstract |
| bklnumber |
44.85 |
| publishDate |
2020 |
| allfields |
10.1016/j.nimb.2019.12.028 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica (DE-627)ELV049340166 (ELSEVIER)S0168-583X(19)30847-X DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.85 bkl Funayama, Tomoo verfasserin aut An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion 2020transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam Elsevier Sakashita, Tetsuya oth Suzuki, Michiyo oth Yokota, Yuichiro oth Miyawaki, Nobumasa oth Kashiwagi, Hirotsugu oth Satoh, Takahiro oth Kurashima, Satoshi oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 https://doi.org/10.1016/j.nimb.2019.12.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 465 2020 15 0215 101-109 9 |
| spelling |
10.1016/j.nimb.2019.12.028 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica (DE-627)ELV049340166 (ELSEVIER)S0168-583X(19)30847-X DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.85 bkl Funayama, Tomoo verfasserin aut An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion 2020transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam Elsevier Sakashita, Tetsuya oth Suzuki, Michiyo oth Yokota, Yuichiro oth Miyawaki, Nobumasa oth Kashiwagi, Hirotsugu oth Satoh, Takahiro oth Kurashima, Satoshi oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 https://doi.org/10.1016/j.nimb.2019.12.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 465 2020 15 0215 101-109 9 |
| allfields_unstemmed |
10.1016/j.nimb.2019.12.028 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica (DE-627)ELV049340166 (ELSEVIER)S0168-583X(19)30847-X DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.85 bkl Funayama, Tomoo verfasserin aut An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion 2020transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam Elsevier Sakashita, Tetsuya oth Suzuki, Michiyo oth Yokota, Yuichiro oth Miyawaki, Nobumasa oth Kashiwagi, Hirotsugu oth Satoh, Takahiro oth Kurashima, Satoshi oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 https://doi.org/10.1016/j.nimb.2019.12.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 465 2020 15 0215 101-109 9 |
| allfieldsGer |
10.1016/j.nimb.2019.12.028 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica (DE-627)ELV049340166 (ELSEVIER)S0168-583X(19)30847-X DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.85 bkl Funayama, Tomoo verfasserin aut An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion 2020transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam Elsevier Sakashita, Tetsuya oth Suzuki, Michiyo oth Yokota, Yuichiro oth Miyawaki, Nobumasa oth Kashiwagi, Hirotsugu oth Satoh, Takahiro oth Kurashima, Satoshi oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 https://doi.org/10.1016/j.nimb.2019.12.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 465 2020 15 0215 101-109 9 |
| allfieldsSound |
10.1016/j.nimb.2019.12.028 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica (DE-627)ELV049340166 (ELSEVIER)S0168-583X(19)30847-X DE-627 ger DE-627 rakwb eng 610 VZ 610 VZ 44.85 bkl Funayama, Tomoo verfasserin aut An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion 2020transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam Elsevier Sakashita, Tetsuya oth Suzuki, Michiyo oth Yokota, Yuichiro oth Miyawaki, Nobumasa oth Kashiwagi, Hirotsugu oth Satoh, Takahiro oth Kurashima, Satoshi oth Enthalten in Elsevier Unwala, Darius J. ELSEVIER Editorial Comment 2013 a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics Amsterdam [u.a.] (DE-627)ELV011304669 volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 https://doi.org/10.1016/j.nimb.2019.12.028 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 44.85 Kardiologie Angiologie VZ AR 465 2020 15 0215 101-109 9 |
| language |
English |
| source |
Enthalten in Editorial Comment Amsterdam [u.a.] volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 |
| sourceStr |
Enthalten in Editorial Comment Amsterdam [u.a.] volume:465 year:2020 day:15 month:02 pages:101-109 extent:9 |
| format_phy_str_mv |
Article |
| bklname |
Kardiologie Angiologie |
| institution |
findex.gbv.de |
| topic_facet |
Targeted irradiation of cultured cells High linear energy transfer Targeted irradiation of Caenorhabditis elegans Heavy-ion Microbeam |
| dewey-raw |
610 |
| isfreeaccess_bool |
false |
| container_title |
Editorial Comment |
| authorswithroles_txt_mv |
Funayama, Tomoo @@aut@@ Sakashita, Tetsuya @@oth@@ Suzuki, Michiyo @@oth@@ Yokota, Yuichiro @@oth@@ Miyawaki, Nobumasa @@oth@@ Kashiwagi, Hirotsugu @@oth@@ Satoh, Takahiro @@oth@@ Kurashima, Satoshi @@oth@@ |
| publishDateDaySort_date |
2020-01-15T00:00:00Z |
| hierarchy_top_id |
ELV011304669 |
| dewey-sort |
3610 |
| id |
ELV049340166 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV049340166</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626024113.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">200518s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.nimb.2019.12.028</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV049340166</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0168-583X(19)30847-X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Funayama, Tomoo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">9</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Targeted irradiation of cultured cells</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">High linear energy transfer</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Targeted irradiation of Caenorhabditis elegans</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Heavy-ion</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Microbeam</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sakashita, Tetsuya</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Suzuki, Michiyo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yokota, Yuichiro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Miyawaki, Nobumasa</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kashiwagi, Hirotsugu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Satoh, Takahiro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kurashima, Satoshi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Unwala, Darius J. ELSEVIER</subfield><subfield code="t">Editorial Comment</subfield><subfield code="d">2013</subfield><subfield code="d">a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011304669</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:465</subfield><subfield code="g">year:2020</subfield><subfield code="g">day:15</subfield><subfield code="g">month:02</subfield><subfield code="g">pages:101-109</subfield><subfield code="g">extent:9</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.nimb.2019.12.028</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2001</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.85</subfield><subfield code="j">Kardiologie</subfield><subfield code="j">Angiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">465</subfield><subfield code="j">2020</subfield><subfield code="b">15</subfield><subfield code="c">0215</subfield><subfield code="h">101-109</subfield><subfield code="g">9</subfield></datafield></record></collection>
|
| author |
Funayama, Tomoo |
| spellingShingle |
Funayama, Tomoo ddc 610 bkl 44.85 Elsevier Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| authorStr |
Funayama, Tomoo |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV011304669 |
| format |
electronic Article |
| dewey-ones |
610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
610 VZ 44.85 bkl An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam Elsevier |
| topic |
ddc 610 bkl 44.85 Elsevier Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam |
| topic_unstemmed |
ddc 610 bkl 44.85 Elsevier Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam |
| topic_browse |
ddc 610 bkl 44.85 Elsevier Targeted irradiation of cultured cells Elsevier High linear energy transfer Elsevier Targeted irradiation of Caenorhabditis elegans Elsevier Heavy-ion Elsevier Microbeam |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
t s ts m s ms y y yy n m nm h k hk t s ts s k sk |
| hierarchy_parent_title |
Editorial Comment |
| hierarchy_parent_id |
ELV011304669 |
| dewey-tens |
610 - Medicine & health |
| hierarchy_top_title |
Editorial Comment |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV011304669 |
| title |
An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| ctrlnum |
(DE-627)ELV049340166 (ELSEVIER)S0168-583X(19)30847-X |
| title_full |
An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| author_sort |
Funayama, Tomoo |
| journal |
Editorial Comment |
| journalStr |
Editorial Comment |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
600 - Technology |
| recordtype |
marc |
| publishDateSort |
2020 |
| contenttype_str_mv |
zzz |
| container_start_page |
101 |
| author_browse |
Funayama, Tomoo |
| container_volume |
465 |
| physical |
9 |
| class |
610 VZ 44.85 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Funayama, Tomoo |
| doi_str_mv |
10.1016/j.nimb.2019.12.028 |
| dewey-full |
610 |
| title_sort |
an irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| title_auth |
An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| abstract |
For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. |
| abstractGer |
For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. |
| abstract_unstemmed |
For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA GBV_ILN_21 GBV_ILN_22 GBV_ILN_24 GBV_ILN_40 GBV_ILN_62 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2007 |
| title_short |
An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion |
| url |
https://doi.org/10.1016/j.nimb.2019.12.028 |
| remote_bool |
true |
| author2 |
Sakashita, Tetsuya Suzuki, Michiyo Yokota, Yuichiro Miyawaki, Nobumasa Kashiwagi, Hirotsugu Satoh, Takahiro Kurashima, Satoshi |
| author2Str |
Sakashita, Tetsuya Suzuki, Michiyo Yokota, Yuichiro Miyawaki, Nobumasa Kashiwagi, Hirotsugu Satoh, Takahiro Kurashima, Satoshi |
| ppnlink |
ELV011304669 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth oth oth |
| doi_str |
10.1016/j.nimb.2019.12.028 |
| up_date |
2024-07-06T21:18:24.076Z |
| _version_ |
1803866031079292928 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV049340166</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626024113.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">200518s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.nimb.2019.12.028</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000907.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV049340166</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0168-583X(19)30847-X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.85</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Funayama, Tomoo</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">An irradiation device for biological targets using focused microbeams of cyclotron-accelerated heavy ion</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">9</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">For use in medical and life science research, a device and sample preparation methods were developed to irradiate cultured cells and individual animals with a focused microbeam of cyclotron-accelerated heavy-ions. The new irradiation device positions both sample and microscope with micrometer precision. The beam size is smaller than 3 µm when the distance between the beam exit from vacuum to the irradiation device is less than 500 µm for 13.0 MeV/u 20Ne ions. This beam size is sufficiently small to irradiate intracellular targets in cultured cells. A beam size smaller than 10 µm was obtained for 12C ions of 26.7 MeV/u at a distance of 2 mm from the beam exit, which enabled irradiation of specific cells in a small model animal. Methods to prepare cultured cells and the nematode Caenorhabditis elegans for irradiation using the new device are reported, and the results of the first irradiation experiments presented.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Targeted irradiation of cultured cells</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">High linear energy transfer</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Targeted irradiation of Caenorhabditis elegans</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Heavy-ion</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Microbeam</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sakashita, Tetsuya</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Suzuki, Michiyo</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Yokota, Yuichiro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Miyawaki, Nobumasa</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kashiwagi, Hirotsugu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Satoh, Takahiro</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kurashima, Satoshi</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Unwala, Darius J. ELSEVIER</subfield><subfield code="t">Editorial Comment</subfield><subfield code="d">2013</subfield><subfield code="d">a journal on accelerators, instrumentation and techniques applied to research in nuclear and atomic physics, materials science and related fields in physics</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV011304669</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:465</subfield><subfield code="g">year:2020</subfield><subfield code="g">day:15</subfield><subfield code="g">month:02</subfield><subfield code="g">pages:101-109</subfield><subfield code="g">extent:9</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.nimb.2019.12.028</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_21</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2001</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.85</subfield><subfield code="j">Kardiologie</subfield><subfield code="j">Angiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">465</subfield><subfield code="j">2020</subfield><subfield code="b">15</subfield><subfield code="c">0215</subfield><subfield code="h">101-109</subfield><subfield code="g">9</subfield></datafield></record></collection>
|
| score |
7.3998127 |