Nociceptor–Mast Cell Sensory Clusters as Regulators of Skin Homeostasis
Recent studies revealed the existence of unique functional links between mast cells and nociceptors in the skin. Here, we propose that mast cells and nociceptors form a single regulatory unit in both physiology and disease. In this model, MrgprB2/X2 signaling is a primary mechanism by which mast cel...
Ausführliche Beschreibung
Autor*in: |
Meixiong, James [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Umfang: |
3 |
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Übergeordnetes Werk: |
Enthalten in: Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam - Benkouider, A. ELSEVIER, 2013, TINS, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:43 ; year:2020 ; number:3 ; pages:130-132 ; extent:3 |
Links: |
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DOI / URN: |
10.1016/j.tins.2020.01.001 |
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Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
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Ultimate nanopatterning of Si substrate using filtered liquid metal alloy ion source-focused ion beam |
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Meixiong, James |
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Meixiong, James |
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10.1016/j.tins.2020.01.001 |
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title_sort |
nociceptor–mast cell sensory clusters as regulators of skin homeostasis |
title_auth |
Nociceptor–Mast Cell Sensory Clusters as Regulators of Skin Homeostasis |
abstract |
Recent studies revealed the existence of unique functional links between mast cells and nociceptors in the skin. Here, we propose that mast cells and nociceptors form a single regulatory unit in both physiology and disease. In this model, MrgprB2/X2 signaling is a primary mechanism by which mast cells functionally interact with nociceptors to form specialized neuroimmune clusters that regulate pain, inflammation, and itch. |
abstractGer |
Recent studies revealed the existence of unique functional links between mast cells and nociceptors in the skin. Here, we propose that mast cells and nociceptors form a single regulatory unit in both physiology and disease. In this model, MrgprB2/X2 signaling is a primary mechanism by which mast cells functionally interact with nociceptors to form specialized neuroimmune clusters that regulate pain, inflammation, and itch. |
abstract_unstemmed |
Recent studies revealed the existence of unique functional links between mast cells and nociceptors in the skin. Here, we propose that mast cells and nociceptors form a single regulatory unit in both physiology and disease. In this model, MrgprB2/X2 signaling is a primary mechanism by which mast cells functionally interact with nociceptors to form specialized neuroimmune clusters that regulate pain, inflammation, and itch. |
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container_issue |
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title_short |
Nociceptor–Mast Cell Sensory Clusters as Regulators of Skin Homeostasis |
url |
https://doi.org/10.1016/j.tins.2020.01.001 |
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Basso, Lilian Dong, Xinzhong Gaudenzio, Nicolas |
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up_date |
2024-07-06T21:47:21.283Z |
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