Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells
Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by...
Ausführliche Beschreibung
Gespeichert in:
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Bian, Jing [verfasserIn] |
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E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020transfer abstract |
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| Übergeordnetes Werk: |
Enthalten in: Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling - Abd-Elhady, M.S. ELSEVIER, 2016, including pharmacology letters, New York, NY [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:246 ; year:2020 ; day:1 ; month:04 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1016/j.lfs.2020.117396 |
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| 520 | |a Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. | ||
| 520 | |a Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. | ||
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10.1016/j.lfs.2020.117396 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001862.pica (DE-627)ELV049580396 (ELSEVIER)S0024-3205(20)30143-0 DE-627 ger DE-627 rakwb eng 690 VZ 530 620 VZ 52.56 bkl Bian, Jing verfasserin aut Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. He, Linxiu oth Wu, Yutong oth Liu, Wensi oth Ma, Heyao oth Sun, Mingli oth Yu, Jiankun oth Yu, Zhaojin oth Wei, Minjie oth Enthalten in Elsevier Science Abd-Elhady, M.S. ELSEVIER Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling 2016 including pharmacology letters New York, NY [u.a.] (DE-627)ELV014481960 volume:246 year:2020 day:1 month:04 pages:0 https://doi.org/10.1016/j.lfs.2020.117396 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_40 52.56 Regenerative Energieformen alternative Energieformen VZ AR 246 2020 1 0401 0 |
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10.1016/j.lfs.2020.117396 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001862.pica (DE-627)ELV049580396 (ELSEVIER)S0024-3205(20)30143-0 DE-627 ger DE-627 rakwb eng 690 VZ 530 620 VZ 52.56 bkl Bian, Jing verfasserin aut Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. He, Linxiu oth Wu, Yutong oth Liu, Wensi oth Ma, Heyao oth Sun, Mingli oth Yu, Jiankun oth Yu, Zhaojin oth Wei, Minjie oth Enthalten in Elsevier Science Abd-Elhady, M.S. ELSEVIER Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling 2016 including pharmacology letters New York, NY [u.a.] (DE-627)ELV014481960 volume:246 year:2020 day:1 month:04 pages:0 https://doi.org/10.1016/j.lfs.2020.117396 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_40 52.56 Regenerative Energieformen alternative Energieformen VZ AR 246 2020 1 0401 0 |
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10.1016/j.lfs.2020.117396 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001862.pica (DE-627)ELV049580396 (ELSEVIER)S0024-3205(20)30143-0 DE-627 ger DE-627 rakwb eng 690 VZ 530 620 VZ 52.56 bkl Bian, Jing verfasserin aut Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. He, Linxiu oth Wu, Yutong oth Liu, Wensi oth Ma, Heyao oth Sun, Mingli oth Yu, Jiankun oth Yu, Zhaojin oth Wei, Minjie oth Enthalten in Elsevier Science Abd-Elhady, M.S. ELSEVIER Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling 2016 including pharmacology letters New York, NY [u.a.] (DE-627)ELV014481960 volume:246 year:2020 day:1 month:04 pages:0 https://doi.org/10.1016/j.lfs.2020.117396 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_40 52.56 Regenerative Energieformen alternative Energieformen VZ AR 246 2020 1 0401 0 |
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10.1016/j.lfs.2020.117396 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001862.pica (DE-627)ELV049580396 (ELSEVIER)S0024-3205(20)30143-0 DE-627 ger DE-627 rakwb eng 690 VZ 530 620 VZ 52.56 bkl Bian, Jing verfasserin aut Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. He, Linxiu oth Wu, Yutong oth Liu, Wensi oth Ma, Heyao oth Sun, Mingli oth Yu, Jiankun oth Yu, Zhaojin oth Wei, Minjie oth Enthalten in Elsevier Science Abd-Elhady, M.S. ELSEVIER Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling 2016 including pharmacology letters New York, NY [u.a.] (DE-627)ELV014481960 volume:246 year:2020 day:1 month:04 pages:0 https://doi.org/10.1016/j.lfs.2020.117396 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_40 52.56 Regenerative Energieformen alternative Energieformen VZ AR 246 2020 1 0401 0 |
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10.1016/j.lfs.2020.117396 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001862.pica (DE-627)ELV049580396 (ELSEVIER)S0024-3205(20)30143-0 DE-627 ger DE-627 rakwb eng 690 VZ 530 620 VZ 52.56 bkl Bian, Jing verfasserin aut Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. He, Linxiu oth Wu, Yutong oth Liu, Wensi oth Ma, Heyao oth Sun, Mingli oth Yu, Jiankun oth Yu, Zhaojin oth Wei, Minjie oth Enthalten in Elsevier Science Abd-Elhady, M.S. ELSEVIER Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling 2016 including pharmacology letters New York, NY [u.a.] (DE-627)ELV014481960 volume:246 year:2020 day:1 month:04 pages:0 https://doi.org/10.1016/j.lfs.2020.117396 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_40 52.56 Regenerative Energieformen alternative Energieformen VZ AR 246 2020 1 0401 0 |
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Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling |
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Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells |
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Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells |
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Bian, Jing |
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Transition of convective heat transfer to subcooled flow boiling due to crystallization fouling |
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anterior gradient 2–derived peptide upregulates major histocompatibility complex class i–related chains a/b in hepatocellular carcinoma cells |
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Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells |
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Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. |
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Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. |
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Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide. Decrease in NKG2D ligand levels and exhaustion of NK cells in HCC patients are major causes of immune escape, high recurrence, poor prognosis, and low overall survival. Enhancing the susceptibility of HCC to NK cells by upregulating NKG2DLs on tumor cells is an effective treatment strategy. This study aimed to identify the effect of the Anterior gradient 2 (AGR2)-derived peptide P1, which was reported to bind to HLA-A*0201 as an epitope, on both the expression of major histocompatibility complex class I-related chains A/B (MICA/B) on HCC cells and the cytotoxicity of NK cells. |
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Anterior gradient 2–derived peptide upregulates major histocompatibility complex class I–related chains A/B in hepatocellular carcinoma cells |
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He, Linxiu Wu, Yutong Liu, Wensi Ma, Heyao Sun, Mingli Yu, Jiankun Yu, Zhaojin Wei, Minjie |
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He, Linxiu Wu, Yutong Liu, Wensi Ma, Heyao Sun, Mingli Yu, Jiankun Yu, Zhaojin Wei, Minjie |
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