DNA damage in colon mucosa of Pirc rats, an Apc-driven model of colon tumorigenesis
• Aging is associated with increased DNA damage in colon mucosa. • Pirc mutation is associated with increased oxidative DNA damage in colon mucosa. • Pirc mutation is not associated with an increase in genotoxic colonic bacteria.
Gespeichert in:
| Autor*in: |
Tortora, Katia [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020 |
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| Schlagwörter: |
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| Umfang: |
8 |
|---|
| Übergeordnetes Werk: |
Enthalten in: Toxicology letters - Chen, Yun-Ru ELSEVIER, 2019, an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:324 ; year:2020 ; day:15 ; month:05 ; pages:12-19 ; extent:8 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.toxlet.2020.02.002 |
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DNA damage in colon mucosa of Pirc rats, an Apc-driven model of colon tumorigenesis |
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• Aging is associated with increased DNA damage in colon mucosa. • Pirc mutation is associated with increased oxidative DNA damage in colon mucosa. • Pirc mutation is not associated with an increase in genotoxic colonic bacteria. |
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