Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications
The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their p...
Ausführliche Beschreibung
Autor*in: |
Koneru, Aditya [verfasserIn] |
---|
Format: |
E-Artikel |
---|---|
Sprache: |
Englisch |
Erschienen: |
2020transfer abstract |
---|
Umfang: |
10 |
---|
Übergeordnetes Werk: |
Enthalten in: Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor - Penchovsky, Robert ELSEVIER, 2019, structure, function and interactions, New York, NY [u.a.] |
---|---|
Übergeordnetes Werk: |
volume:148 ; year:2020 ; day:1 ; month:04 ; pages:833-842 ; extent:10 |
Links: |
---|
DOI / URN: |
10.1016/j.ijbiomac.2020.01.018 |
---|
Katalog-ID: |
ELV049606107 |
---|
LEADER | 01000caa a22002652 4500 | ||
---|---|---|---|
001 | ELV049606107 | ||
003 | DE-627 | ||
005 | 20230626024738.0 | ||
007 | cr uuu---uuuuu | ||
008 | 200518s2020 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1016/j.ijbiomac.2020.01.018 |2 doi | |
028 | 5 | 2 | |a /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica |
035 | |a (DE-627)ELV049606107 | ||
035 | |a (ELSEVIER)S0141-8130(19)37246-0 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
082 | 0 | 4 | |a 570 |a 610 |q VZ |
084 | |a 58.30 |2 bkl | ||
084 | |a 50.22 |2 bkl | ||
084 | |a 44.09 |2 bkl | ||
100 | 1 | |a Koneru, Aditya |e verfasserin |4 aut | |
245 | 1 | 0 | |a Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
264 | 1 | |c 2020transfer abstract | |
300 | |a 10 | ||
336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
337 | |a nicht spezifiziert |b z |2 rdamedia | ||
338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
520 | |a The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. | ||
520 | |a The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. | ||
700 | 1 | |a Dharmalingam, K. |4 oth | |
700 | 1 | |a Anandalakshmi, R. |4 oth | |
773 | 0 | 8 | |i Enthalten in |n Elsevier |a Penchovsky, Robert ELSEVIER |t Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor |d 2019 |d structure, function and interactions |g New York, NY [u.a.] |w (DE-627)ELV002200198 |
773 | 1 | 8 | |g volume:148 |g year:2020 |g day:1 |g month:04 |g pages:833-842 |g extent:10 |
856 | 4 | 0 | |u https://doi.org/10.1016/j.ijbiomac.2020.01.018 |3 Volltext |
912 | |a GBV_USEFLAG_U | ||
912 | |a GBV_ELV | ||
912 | |a SYSFLAG_U | ||
912 | |a SSG-OLC-PHA | ||
936 | b | k | |a 58.30 |j Biotechnologie |q VZ |
936 | b | k | |a 50.22 |j Sensorik |q VZ |
936 | b | k | |a 44.09 |j Medizintechnik |q VZ |
951 | |a AR | ||
952 | |d 148 |j 2020 |b 1 |c 0401 |h 833-842 |g 10 |
author_variant |
a k ak |
---|---|
matchkey_str |
koneruadityadharmalingamkanandalakshmir:2020----:ellsbsdaoopsthdoeflsossigfoimabxmtycluoerpfutedxrcnnpri |
hierarchy_sort_str |
2020transfer abstract |
bklnumber |
58.30 50.22 44.09 |
publishDate |
2020 |
allfields |
10.1016/j.ijbiomac.2020.01.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica (DE-627)ELV049606107 (ELSEVIER)S0141-8130(19)37246-0 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Koneru, Aditya verfasserin aut Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications 2020transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. Dharmalingam, K. oth Anandalakshmi, R. oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 https://doi.org/10.1016/j.ijbiomac.2020.01.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 148 2020 1 0401 833-842 10 |
spelling |
10.1016/j.ijbiomac.2020.01.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica (DE-627)ELV049606107 (ELSEVIER)S0141-8130(19)37246-0 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Koneru, Aditya verfasserin aut Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications 2020transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. Dharmalingam, K. oth Anandalakshmi, R. oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 https://doi.org/10.1016/j.ijbiomac.2020.01.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 148 2020 1 0401 833-842 10 |
allfields_unstemmed |
10.1016/j.ijbiomac.2020.01.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica (DE-627)ELV049606107 (ELSEVIER)S0141-8130(19)37246-0 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Koneru, Aditya verfasserin aut Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications 2020transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. Dharmalingam, K. oth Anandalakshmi, R. oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 https://doi.org/10.1016/j.ijbiomac.2020.01.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 148 2020 1 0401 833-842 10 |
allfieldsGer |
10.1016/j.ijbiomac.2020.01.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica (DE-627)ELV049606107 (ELSEVIER)S0141-8130(19)37246-0 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Koneru, Aditya verfasserin aut Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications 2020transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. Dharmalingam, K. oth Anandalakshmi, R. oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 https://doi.org/10.1016/j.ijbiomac.2020.01.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 148 2020 1 0401 833-842 10 |
allfieldsSound |
10.1016/j.ijbiomac.2020.01.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica (DE-627)ELV049606107 (ELSEVIER)S0141-8130(19)37246-0 DE-627 ger DE-627 rakwb eng 570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Koneru, Aditya verfasserin aut Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications 2020transfer abstract 10 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. Dharmalingam, K. oth Anandalakshmi, R. oth Enthalten in Elsevier Penchovsky, Robert ELSEVIER Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor 2019 structure, function and interactions New York, NY [u.a.] (DE-627)ELV002200198 volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 https://doi.org/10.1016/j.ijbiomac.2020.01.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 58.30 Biotechnologie VZ 50.22 Sensorik VZ 44.09 Medizintechnik VZ AR 148 2020 1 0401 833-842 10 |
language |
English |
source |
Enthalten in Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor New York, NY [u.a.] volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 |
sourceStr |
Enthalten in Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor New York, NY [u.a.] volume:148 year:2020 day:1 month:04 pages:833-842 extent:10 |
format_phy_str_mv |
Article |
bklname |
Biotechnologie Sensorik Medizintechnik |
institution |
findex.gbv.de |
dewey-raw |
570 |
isfreeaccess_bool |
false |
container_title |
Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor |
authorswithroles_txt_mv |
Koneru, Aditya @@aut@@ Dharmalingam, K. @@oth@@ Anandalakshmi, R. @@oth@@ |
publishDateDaySort_date |
2020-01-01T00:00:00Z |
hierarchy_top_id |
ELV002200198 |
dewey-sort |
3570 |
id |
ELV049606107 |
language_de |
englisch |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV049606107</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626024738.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">200518s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ijbiomac.2020.01.018</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV049606107</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0141-8130(19)37246-0</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">50.22</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.09</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Koneru, Aditya</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">10</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dharmalingam, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Anandalakshmi, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Penchovsky, Robert ELSEVIER</subfield><subfield code="t">Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor</subfield><subfield code="d">2019</subfield><subfield code="d">structure, function and interactions</subfield><subfield code="g">New York, NY [u.a.]</subfield><subfield code="w">(DE-627)ELV002200198</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:148</subfield><subfield code="g">year:2020</subfield><subfield code="g">day:1</subfield><subfield code="g">month:04</subfield><subfield code="g">pages:833-842</subfield><subfield code="g">extent:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.ijbiomac.2020.01.018</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.30</subfield><subfield code="j">Biotechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">50.22</subfield><subfield code="j">Sensorik</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.09</subfield><subfield code="j">Medizintechnik</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">148</subfield><subfield code="j">2020</subfield><subfield code="b">1</subfield><subfield code="c">0401</subfield><subfield code="h">833-842</subfield><subfield code="g">10</subfield></datafield></record></collection>
|
author |
Koneru, Aditya |
spellingShingle |
Koneru, Aditya ddc 570 bkl 58.30 bkl 50.22 bkl 44.09 Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
authorStr |
Koneru, Aditya |
ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV002200198 |
format |
electronic Article |
dewey-ones |
570 - Life sciences; biology 610 - Medicine & health |
delete_txt_mv |
keep |
author_role |
aut |
collection |
elsevier |
remote_str |
true |
illustrated |
Not Illustrated |
topic_title |
570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
topic |
ddc 570 bkl 58.30 bkl 50.22 bkl 44.09 |
topic_unstemmed |
ddc 570 bkl 58.30 bkl 50.22 bkl 44.09 |
topic_browse |
ddc 570 bkl 58.30 bkl 50.22 bkl 44.09 |
format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
format_main_str_mv |
Text Zeitschrift/Artikel |
carriertype_str_mv |
zu |
author2_variant |
k d kd r a ra |
hierarchy_parent_title |
Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor |
hierarchy_parent_id |
ELV002200198 |
dewey-tens |
570 - Life sciences; biology 610 - Medicine & health |
hierarchy_top_title |
Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor |
isfreeaccess_txt |
false |
familylinks_str_mv |
(DE-627)ELV002200198 |
title |
Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
ctrlnum |
(DE-627)ELV049606107 (ELSEVIER)S0141-8130(19)37246-0 |
title_full |
Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
author_sort |
Koneru, Aditya |
journal |
Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor |
journalStr |
Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor |
lang_code |
eng |
isOA_bool |
false |
dewey-hundreds |
500 - Science 600 - Technology |
recordtype |
marc |
publishDateSort |
2020 |
contenttype_str_mv |
zzz |
container_start_page |
833 |
author_browse |
Koneru, Aditya |
container_volume |
148 |
physical |
10 |
class |
570 610 VZ 58.30 bkl 50.22 bkl 44.09 bkl |
format_se |
Elektronische Aufsätze |
author-letter |
Koneru, Aditya |
doi_str_mv |
10.1016/j.ijbiomac.2020.01.018 |
dewey-full |
570 610 |
title_sort |
cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
title_auth |
Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
abstract |
The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. |
abstractGer |
The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. |
abstract_unstemmed |
The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications. |
collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
title_short |
Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications |
url |
https://doi.org/10.1016/j.ijbiomac.2020.01.018 |
remote_bool |
true |
author2 |
Dharmalingam, K. Anandalakshmi, R. |
author2Str |
Dharmalingam, K. Anandalakshmi, R. |
ppnlink |
ELV002200198 |
mediatype_str_mv |
z |
isOA_txt |
false |
hochschulschrift_bool |
false |
author2_role |
oth oth |
doi_str |
10.1016/j.ijbiomac.2020.01.018 |
up_date |
2024-07-06T22:03:06.115Z |
_version_ |
1803868843399970816 |
fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV049606107</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626024738.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">200518s2020 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ijbiomac.2020.01.018</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000934.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV049606107</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0141-8130(19)37246-0</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">570</subfield><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">50.22</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.09</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Koneru, Aditya</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Cellulose based nanocomposite hydrogel films consisting of sodium carboxymethylcellulose–grapefruit seed extract nanoparticles for potential wound healing applications</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2020transfer abstract</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">10</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The impact of grapefruit seed extract (GFSE) as an antibacterial agent on citric acid (CA) crosslinked sodium carboxymethylcellulose (NaCMC)/hydroxypropylmethylcellulose (HPMC) hydrogel films has been studied by incorporating different quantities of GFSE. The prepared films were examined for their physical, thermal, mechanical and antibacterial properties. It was observed that crystallinity and initial decomposition temperature of hydrogel films decreased with GFSE concentration. Furthermore, the swelling degree and tensile strength of hydrogel films were found to be 257.29 ± 5.08%–162.06 ± 1.78% and 11.61 ± 0.27–2.21 ± 0.94 MPa for increasing GFSE concentration varying from 0.25% - 1.5% (v/v). The presence of nanoparticles in the films was observed by FESEM and FETEM analysis. It was confirmed that the formation of nanoparticles (micelles) is due to the addition of NaCMC and GFSE, probably glycerides, which is one of the main components in GFSE. The hydrogel films have demonstrated excellent antimicrobial activity and elongation at break (%). Moreover, zeta potential of nanoparticles was recorded to be −55.26 mV ascertaining their stability in water that contributed to a higher antimicrobial activity against gram negative bacteria. All these outcomes prove the nanocomposite films to be a potential substitute for hydrogels loaded with synthetic drugs in wound healing and other biological applications.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dharmalingam, K.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Anandalakshmi, R.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Penchovsky, Robert ELSEVIER</subfield><subfield code="t">Automated DNA hybridization transfer with movable super-paramagnetic microbeads in a microflow reactor</subfield><subfield code="d">2019</subfield><subfield code="d">structure, function and interactions</subfield><subfield code="g">New York, NY [u.a.]</subfield><subfield code="w">(DE-627)ELV002200198</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:148</subfield><subfield code="g">year:2020</subfield><subfield code="g">day:1</subfield><subfield code="g">month:04</subfield><subfield code="g">pages:833-842</subfield><subfield code="g">extent:10</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.ijbiomac.2020.01.018</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.30</subfield><subfield code="j">Biotechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">50.22</subfield><subfield code="j">Sensorik</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.09</subfield><subfield code="j">Medizintechnik</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">148</subfield><subfield code="j">2020</subfield><subfield code="b">1</subfield><subfield code="c">0401</subfield><subfield code="h">833-842</subfield><subfield code="g">10</subfield></datafield></record></collection>
|
score |
7.398122 |