Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain
• Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to...
Ausführliche Beschreibung
Autor*in: |
Jung, Susan [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Übergeordnetes Werk: |
Enthalten in: DNA methylation mediates gonadal development via regulating the expression levels of - Su, Junxiao ELSEVIER, 2023, an international multidisciplinary journal devoted to fundamental research in the brain sciences, Amsterdam |
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Übergeordnetes Werk: |
volume:1735 ; year:2020 ; day:15 ; month:05 ; pages:0 |
Links: |
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DOI / URN: |
10.1016/j.brainres.2020.146760 |
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Katalog-ID: |
ELV049699377 |
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10.1016/j.brainres.2020.146760 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000966.pica (DE-627)ELV049699377 (ELSEVIER)S0006-8993(20)30116-5 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Jung, Susan verfasserin aut Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain 2020 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. CC3 Elsevier GluR Elsevier BNIP-3 Elsevier SVZ Elsevier HC Elsevier DUSP-1 Elsevier AMPAR Elsevier Ballheimer, Yili E. oth Brackmann, Florian oth Zoglauer, Daniel oth Geppert, Carol-Immanuel oth Hartmann, Arndt oth Trollmann, Regina oth Enthalten in Elsevier Su, Junxiao ELSEVIER DNA methylation mediates gonadal development via regulating the expression levels of 2023 an international multidisciplinary journal devoted to fundamental research in the brain sciences Amsterdam (DE-627)ELV010071113 volume:1735 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.brainres.2020.146760 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 1735 2020 15 0515 0 |
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10.1016/j.brainres.2020.146760 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000966.pica (DE-627)ELV049699377 (ELSEVIER)S0006-8993(20)30116-5 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Jung, Susan verfasserin aut Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain 2020 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. CC3 Elsevier GluR Elsevier BNIP-3 Elsevier SVZ Elsevier HC Elsevier DUSP-1 Elsevier AMPAR Elsevier Ballheimer, Yili E. oth Brackmann, Florian oth Zoglauer, Daniel oth Geppert, Carol-Immanuel oth Hartmann, Arndt oth Trollmann, Regina oth Enthalten in Elsevier Su, Junxiao ELSEVIER DNA methylation mediates gonadal development via regulating the expression levels of 2023 an international multidisciplinary journal devoted to fundamental research in the brain sciences Amsterdam (DE-627)ELV010071113 volume:1735 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.brainres.2020.146760 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 1735 2020 15 0515 0 |
allfields_unstemmed |
10.1016/j.brainres.2020.146760 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000966.pica (DE-627)ELV049699377 (ELSEVIER)S0006-8993(20)30116-5 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Jung, Susan verfasserin aut Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain 2020 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. CC3 Elsevier GluR Elsevier BNIP-3 Elsevier SVZ Elsevier HC Elsevier DUSP-1 Elsevier AMPAR Elsevier Ballheimer, Yili E. oth Brackmann, Florian oth Zoglauer, Daniel oth Geppert, Carol-Immanuel oth Hartmann, Arndt oth Trollmann, Regina oth Enthalten in Elsevier Su, Junxiao ELSEVIER DNA methylation mediates gonadal development via regulating the expression levels of 2023 an international multidisciplinary journal devoted to fundamental research in the brain sciences Amsterdam (DE-627)ELV010071113 volume:1735 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.brainres.2020.146760 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 1735 2020 15 0515 0 |
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10.1016/j.brainres.2020.146760 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000966.pica (DE-627)ELV049699377 (ELSEVIER)S0006-8993(20)30116-5 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Jung, Susan verfasserin aut Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain 2020 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. CC3 Elsevier GluR Elsevier BNIP-3 Elsevier SVZ Elsevier HC Elsevier DUSP-1 Elsevier AMPAR Elsevier Ballheimer, Yili E. oth Brackmann, Florian oth Zoglauer, Daniel oth Geppert, Carol-Immanuel oth Hartmann, Arndt oth Trollmann, Regina oth Enthalten in Elsevier Su, Junxiao ELSEVIER DNA methylation mediates gonadal development via regulating the expression levels of 2023 an international multidisciplinary journal devoted to fundamental research in the brain sciences Amsterdam (DE-627)ELV010071113 volume:1735 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.brainres.2020.146760 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 1735 2020 15 0515 0 |
allfieldsSound |
10.1016/j.brainres.2020.146760 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000000966.pica (DE-627)ELV049699377 (ELSEVIER)S0006-8993(20)30116-5 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Jung, Susan verfasserin aut Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain 2020 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. CC3 Elsevier GluR Elsevier BNIP-3 Elsevier SVZ Elsevier HC Elsevier DUSP-1 Elsevier AMPAR Elsevier Ballheimer, Yili E. oth Brackmann, Florian oth Zoglauer, Daniel oth Geppert, Carol-Immanuel oth Hartmann, Arndt oth Trollmann, Regina oth Enthalten in Elsevier Su, Junxiao ELSEVIER DNA methylation mediates gonadal development via regulating the expression levels of 2023 an international multidisciplinary journal devoted to fundamental research in the brain sciences Amsterdam (DE-627)ELV010071113 volume:1735 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.brainres.2020.146760 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 1735 2020 15 0515 0 |
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Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain |
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• Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. |
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• Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. |
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• Expression kinetics of AMPAR subunits and their mRNA-editing adenosine deaminases are developmentally regulated. • Recurrent neonatal seizures significantly reduce GluR2 mRNA-editing enzymes ADAR1 and ADAR2 in a time- and region-specific manner. • Seizure-induced ADAR2 downregulation is related to region-specific activation of apoptosis. |
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Seizure-induced neuronal apoptosis is related to dysregulation of the RNA-edited GluR2 subunit in the developing mouse brain |
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https://doi.org/10.1016/j.brainres.2020.146760 |
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Ballheimer, Yili E. Brackmann, Florian Zoglauer, Daniel Geppert, Carol-Immanuel Hartmann, Arndt Trollmann, Regina |
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Ballheimer, Yili E. Brackmann, Florian Zoglauer, Daniel Geppert, Carol-Immanuel Hartmann, Arndt Trollmann, Regina |
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doi_str |
10.1016/j.brainres.2020.146760 |
up_date |
2024-07-06T22:18:19.758Z |
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