Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe
Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Zhang, Ziping [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2020transfer abstract |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Association between binge eating disorder and psychiatric comorbidity profiles in patients with obesity seeking bariatric surgery - Borgès Da Silva, Virginie ELSEVIER, 2018, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:311 ; year:2020 ; day:15 ; month:05 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1016/j.snb.2020.127920 |
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ELV049731297 |
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| 520 | |a Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). | ||
| 520 | |a Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). | ||
| 650 | 7 | |a Bivalent enhancement |2 Elsevier | |
| 650 | 7 | |a Split aptamer |2 Elsevier | |
| 650 | 7 | |a DNA scaffold |2 Elsevier | |
| 650 | 7 | |a Sandwich electrochemical sensor |2 Elsevier | |
| 700 | 1 | |a Zhao, Xiaoxia |4 oth | |
| 700 | 1 | |a Liu, Jia |4 oth | |
| 700 | 1 | |a Yin, Jungang |4 oth | |
| 700 | 1 | |a Cao, Xiaolin |4 oth | |
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10.1016/j.snb.2020.127920 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001112.pica (DE-627)ELV049731297 (ELSEVIER)S0925-4005(20)30268-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.91 bkl Zhang, Ziping verfasserin aut Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Bivalent enhancement Elsevier Split aptamer Elsevier DNA scaffold Elsevier Sandwich electrochemical sensor Elsevier Zhao, Xiaoxia oth Liu, Jia oth Yin, Jungang oth Cao, Xiaolin oth Enthalten in Elsevier Science Borgès Da Silva, Virginie ELSEVIER Association between binge eating disorder and psychiatric comorbidity profiles in patients with obesity seeking bariatric surgery 2018 Amsterdam [u.a.] (DE-627)ELV001079875 volume:311 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.snb.2020.127920 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 311 2020 15 0515 0 |
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10.1016/j.snb.2020.127920 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001112.pica (DE-627)ELV049731297 (ELSEVIER)S0925-4005(20)30268-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.91 bkl Zhang, Ziping verfasserin aut Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Bivalent enhancement Elsevier Split aptamer Elsevier DNA scaffold Elsevier Sandwich electrochemical sensor Elsevier Zhao, Xiaoxia oth Liu, Jia oth Yin, Jungang oth Cao, Xiaolin oth Enthalten in Elsevier Science Borgès Da Silva, Virginie ELSEVIER Association between binge eating disorder and psychiatric comorbidity profiles in patients with obesity seeking bariatric surgery 2018 Amsterdam [u.a.] (DE-627)ELV001079875 volume:311 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.snb.2020.127920 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 311 2020 15 0515 0 |
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10.1016/j.snb.2020.127920 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001112.pica (DE-627)ELV049731297 (ELSEVIER)S0925-4005(20)30268-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.91 bkl Zhang, Ziping verfasserin aut Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Bivalent enhancement Elsevier Split aptamer Elsevier DNA scaffold Elsevier Sandwich electrochemical sensor Elsevier Zhao, Xiaoxia oth Liu, Jia oth Yin, Jungang oth Cao, Xiaolin oth Enthalten in Elsevier Science Borgès Da Silva, Virginie ELSEVIER Association between binge eating disorder and psychiatric comorbidity profiles in patients with obesity seeking bariatric surgery 2018 Amsterdam [u.a.] (DE-627)ELV001079875 volume:311 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.snb.2020.127920 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 311 2020 15 0515 0 |
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10.1016/j.snb.2020.127920 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001112.pica (DE-627)ELV049731297 (ELSEVIER)S0925-4005(20)30268-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.91 bkl Zhang, Ziping verfasserin aut Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Bivalent enhancement Elsevier Split aptamer Elsevier DNA scaffold Elsevier Sandwich electrochemical sensor Elsevier Zhao, Xiaoxia oth Liu, Jia oth Yin, Jungang oth Cao, Xiaolin oth Enthalten in Elsevier Science Borgès Da Silva, Virginie ELSEVIER Association between binge eating disorder and psychiatric comorbidity profiles in patients with obesity seeking bariatric surgery 2018 Amsterdam [u.a.] (DE-627)ELV001079875 volume:311 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.snb.2020.127920 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 311 2020 15 0515 0 |
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10.1016/j.snb.2020.127920 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001112.pica (DE-627)ELV049731297 (ELSEVIER)S0925-4005(20)30268-9 DE-627 ger DE-627 rakwb eng 610 VZ 44.91 bkl Zhang, Ziping verfasserin aut Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). Bivalent enhancement Elsevier Split aptamer Elsevier DNA scaffold Elsevier Sandwich electrochemical sensor Elsevier Zhao, Xiaoxia oth Liu, Jia oth Yin, Jungang oth Cao, Xiaolin oth Enthalten in Elsevier Science Borgès Da Silva, Virginie ELSEVIER Association between binge eating disorder and psychiatric comorbidity profiles in patients with obesity seeking bariatric surgery 2018 Amsterdam [u.a.] (DE-627)ELV001079875 volume:311 year:2020 day:15 month:05 pages:0 https://doi.org/10.1016/j.snb.2020.127920 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.91 Psychiatrie Psychopathologie VZ AR 311 2020 15 0515 0 |
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Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe |
| abstract |
Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). |
| abstractGer |
Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). |
| abstract_unstemmed |
Here, we report a convenient and highly sensitive sandwich electrochemical sensor based on a new conception of bivalent split aptamer signal probe (for example S2D1S2), which is readily engineered through a simple hybridization of two identical monovalent split aptamers (S2) to a DNA template strand (D1). Because of the bivalence cooperativity enhanced sandwich binding to target molecules, this type of DNA-scaffolded bivalent signal probe exhibits significantly improved signal increase (SI) for sandwich electrochemical detection of target molecules in comparison with the conventional monovalent counterparts (S1). |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA |
| title_short |
Highly sensitive sandwich electrochemical sensor based on DNA-scaffolded bivalent split aptamer signal probe |
| url |
https://doi.org/10.1016/j.snb.2020.127920 |
| remote_bool |
true |
| author2 |
Zhao, Xiaoxia Liu, Jia Yin, Jungang Cao, Xiaolin |
| author2Str |
Zhao, Xiaoxia Liu, Jia Yin, Jungang Cao, Xiaolin |
| ppnlink |
ELV001079875 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth |
| doi_str |
10.1016/j.snb.2020.127920 |
| up_date |
2024-07-06T22:22:43.788Z |
| _version_ |
1803870078280663040 |
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| score |
7.403078 |