Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer
To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients...
Ausführliche Beschreibung
Autor*in: |
O'Malley, David M. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2020 |
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Umfang: |
7 |
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Übergeordnetes Werk: |
Enthalten in: Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes - Gibson, Diane M. ELSEVIER, 2017, an international journal : official publication of the Society of Gynecologic Oncologists [u.a.], Orlando, Fla |
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Übergeordnetes Werk: |
volume:157 ; year:2020 ; number:2 ; pages:379-385 ; extent:7 |
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DOI / URN: |
10.1016/j.ygyno.2020.01.037 |
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10.1016/j.ygyno.2020.01.037 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050186353 (ELSEVIER)S0090-8258(20)30090-1 DE-627 ger DE-627 rakwb eng 610 VZ 44.11 bkl O'Malley, David M. verfasserin aut Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer 2020 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. Matulonis, Ursula A. oth Birrer, Michael J. oth Castro, Cesar M. oth Gilbert, Lucy oth Vergote, Ignace oth Martin, Lainie P. oth Mantia-Smaldone, Gina M. oth Martin, Antonio González oth Bratos, Raquel oth Penson, Richard T. oth Malek, Karim oth Moore, Kathleen N. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:157 year:2020 number:2 pages:379-385 extent:7 https://doi.org/10.1016/j.ygyno.2020.01.037 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 157 2020 2 379-385 7 |
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10.1016/j.ygyno.2020.01.037 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050186353 (ELSEVIER)S0090-8258(20)30090-1 DE-627 ger DE-627 rakwb eng 610 VZ 44.11 bkl O'Malley, David M. verfasserin aut Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer 2020 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. Matulonis, Ursula A. oth Birrer, Michael J. oth Castro, Cesar M. oth Gilbert, Lucy oth Vergote, Ignace oth Martin, Lainie P. oth Mantia-Smaldone, Gina M. oth Martin, Antonio González oth Bratos, Raquel oth Penson, Richard T. oth Malek, Karim oth Moore, Kathleen N. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:157 year:2020 number:2 pages:379-385 extent:7 https://doi.org/10.1016/j.ygyno.2020.01.037 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 157 2020 2 379-385 7 |
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10.1016/j.ygyno.2020.01.037 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050186353 (ELSEVIER)S0090-8258(20)30090-1 DE-627 ger DE-627 rakwb eng 610 VZ 44.11 bkl O'Malley, David M. verfasserin aut Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer 2020 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. Matulonis, Ursula A. oth Birrer, Michael J. oth Castro, Cesar M. oth Gilbert, Lucy oth Vergote, Ignace oth Martin, Lainie P. oth Mantia-Smaldone, Gina M. oth Martin, Antonio González oth Bratos, Raquel oth Penson, Richard T. oth Malek, Karim oth Moore, Kathleen N. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:157 year:2020 number:2 pages:379-385 extent:7 https://doi.org/10.1016/j.ygyno.2020.01.037 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 157 2020 2 379-385 7 |
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10.1016/j.ygyno.2020.01.037 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050186353 (ELSEVIER)S0090-8258(20)30090-1 DE-627 ger DE-627 rakwb eng 610 VZ 44.11 bkl O'Malley, David M. verfasserin aut Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer 2020 7 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. Matulonis, Ursula A. oth Birrer, Michael J. oth Castro, Cesar M. oth Gilbert, Lucy oth Vergote, Ignace oth Martin, Lainie P. oth Mantia-Smaldone, Gina M. oth Martin, Antonio González oth Bratos, Raquel oth Penson, Richard T. oth Malek, Karim oth Moore, Kathleen N. oth Enthalten in Academic Press Gibson, Diane M. ELSEVIER Frequency and predictors of missed visits to primary care and eye care providers for annually recommended diabetes preventive care services over a two-year period among U.S. adults with diabetes 2017 an international journal : official publication of the Society of Gynecologic Oncologists [u.a.] Orlando, Fla (DE-627)ELV000708127 volume:157 year:2020 number:2 pages:379-385 extent:7 https://doi.org/10.1016/j.ygyno.2020.01.037 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.11 Präventivmedizin VZ AR 157 2020 2 379-385 7 |
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phase ib study of mirvetuximab soravtansine, a folate receptor alpha (frα)-targeting antibody-drug conjugate (adc), in combination with bevacizumab in patients with platinum-resistant ovarian cancer |
title_auth |
Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer |
abstract |
To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. |
abstractGer |
To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. |
abstract_unstemmed |
To evaluate the safety and clinical activity of mirvetuximab soravtansine, an antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) monoclonal antibody, cleavable linker, and the maytansinoid DM4, a potent tubulin-targeting agent, in combination with bevacizumab in patients with FRα-positive, platinum-resistant ovarian cancer. |
collection_details |
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container_issue |
2 |
title_short |
Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer |
url |
https://doi.org/10.1016/j.ygyno.2020.01.037 |
remote_bool |
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author2 |
Matulonis, Ursula A. Birrer, Michael J. Castro, Cesar M. Gilbert, Lucy Vergote, Ignace Martin, Lainie P. Mantia-Smaldone, Gina M. Martin, Antonio González Bratos, Raquel Penson, Richard T. Malek, Karim Moore, Kathleen N. |
author2Str |
Matulonis, Ursula A. Birrer, Michael J. Castro, Cesar M. Gilbert, Lucy Vergote, Ignace Martin, Lainie P. Mantia-Smaldone, Gina M. Martin, Antonio González Bratos, Raquel Penson, Richard T. Malek, Karim Moore, Kathleen N. |
ppnlink |
ELV000708127 |
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hochschulschrift_bool |
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author2_role |
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doi_str |
10.1016/j.ygyno.2020.01.037 |
up_date |
2024-07-06T16:50:41.425Z |
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