Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017)

The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Pfaller, Michael A. [verfasserIn] Carvalhaes, Cecilia G. Smith, Caitlin J. Diekema, Daniel J. Castanheira, Mariana

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020transfer abstract

Übergeordnetes Werk:	Enthalten in: Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications - Rodrigues, Jéssica S. ELSEVIER, 2023, Amsterdam [u.a.]
Übergeordnetes Werk:	volume:97 ; year:2020 ; number:2 ; pages:0

Links:	Volltext

DOI / URN:	10.1016/j.diagmicrobio.2020.115016

Katalog-ID:	ELV050239406

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245	1	0	\|a Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017)
264		1	\|c 2020transfer abstract
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520			\|a The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.
520			\|a The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.
700	1		\|a Carvalhaes, Cecilia G. \|4 oth
700	1		\|a Smith, Caitlin J. \|4 oth
700	1		\|a Diekema, Daniel J. \|4 oth
700	1		\|a Castanheira, Mariana \|4 oth
773	0	8	\|i Enthalten in \|n Elsevier Science \|a Rodrigues, Jéssica S. ELSEVIER \|t Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications \|d 2023 \|g Amsterdam [u.a.] \|w (DE-627)ELV009877355
773	1	8	\|g volume:97 \|g year:2020 \|g number:2 \|g pages:0
856	4	0	\|u https://doi.org/10.1016/j.diagmicrobio.2020.115016 \|3 Volltext
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936	b	k	\|a 35.80 \|j Makromolekulare Chemie \|q VZ
936	b	k	\|a 58.30 \|j Biotechnologie \|q VZ
951			\|a AR
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Indexfelder

author_variant	m a p ma map
matchkey_str	pfallermichaelacarvalhaesceciliagsmithca:2020----:atraaduglahgnioaefoptetwtbodtemnetofeunyfcurnenatmcoilucpiiiyatrsrm
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bklnumber	35.80 58.30
publishDate	2020
allfields	10.1016/j.diagmicrobio.2020.115016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050239406 (ELSEVIER)S0732-8893(19)31093-4 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Pfaller, Michael A. verfasserin aut Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017) 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. Carvalhaes, Cecilia G. oth Smith, Caitlin J. oth Diekema, Daniel J. oth Castanheira, Mariana oth Enthalten in Elsevier Science Rodrigues, Jéssica S. ELSEVIER Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications 2023 Amsterdam [u.a.] (DE-627)ELV009877355 volume:97 year:2020 number:2 pages:0 https://doi.org/10.1016/j.diagmicrobio.2020.115016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 97 2020 2 0
spelling	10.1016/j.diagmicrobio.2020.115016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050239406 (ELSEVIER)S0732-8893(19)31093-4 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Pfaller, Michael A. verfasserin aut Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017) 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. Carvalhaes, Cecilia G. oth Smith, Caitlin J. oth Diekema, Daniel J. oth Castanheira, Mariana oth Enthalten in Elsevier Science Rodrigues, Jéssica S. ELSEVIER Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications 2023 Amsterdam [u.a.] (DE-627)ELV009877355 volume:97 year:2020 number:2 pages:0 https://doi.org/10.1016/j.diagmicrobio.2020.115016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 97 2020 2 0
allfields_unstemmed	10.1016/j.diagmicrobio.2020.115016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050239406 (ELSEVIER)S0732-8893(19)31093-4 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Pfaller, Michael A. verfasserin aut Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017) 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. Carvalhaes, Cecilia G. oth Smith, Caitlin J. oth Diekema, Daniel J. oth Castanheira, Mariana oth Enthalten in Elsevier Science Rodrigues, Jéssica S. ELSEVIER Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications 2023 Amsterdam [u.a.] (DE-627)ELV009877355 volume:97 year:2020 number:2 pages:0 https://doi.org/10.1016/j.diagmicrobio.2020.115016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 97 2020 2 0
allfieldsGer	10.1016/j.diagmicrobio.2020.115016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050239406 (ELSEVIER)S0732-8893(19)31093-4 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Pfaller, Michael A. verfasserin aut Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017) 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. Carvalhaes, Cecilia G. oth Smith, Caitlin J. oth Diekema, Daniel J. oth Castanheira, Mariana oth Enthalten in Elsevier Science Rodrigues, Jéssica S. ELSEVIER Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications 2023 Amsterdam [u.a.] (DE-627)ELV009877355 volume:97 year:2020 number:2 pages:0 https://doi.org/10.1016/j.diagmicrobio.2020.115016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 97 2020 2 0
allfieldsSound	10.1016/j.diagmicrobio.2020.115016 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001004.pica (DE-627)ELV050239406 (ELSEVIER)S0732-8893(19)31093-4 DE-627 ger DE-627 rakwb eng 540 570 VZ BIODIV DE-30 fid 35.80 bkl 58.30 bkl Pfaller, Michael A. verfasserin aut Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017) 2020transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015. Carvalhaes, Cecilia G. oth Smith, Caitlin J. oth Diekema, Daniel J. oth Castanheira, Mariana oth Enthalten in Elsevier Science Rodrigues, Jéssica S. ELSEVIER Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications 2023 Amsterdam [u.a.] (DE-627)ELV009877355 volume:97 year:2020 number:2 pages:0 https://doi.org/10.1016/j.diagmicrobio.2020.115016 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.80 Makromolekulare Chemie VZ 58.30 Biotechnologie VZ AR 97 2020 2 0
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title_sort	bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the sentry antimicrobial surveillance program (2012–2017)
title_auth	Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017)
abstract	The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.
abstractGer	The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.
abstract_unstemmed	The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.
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title_short	Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017)
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In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The SENTRY Antimicrobial Surveillance Program has monitored bloodstream infections (BSIs) from patients in medical centers worldwide since 1997. In this report, we examine the frequency of occurrence and antimicrobial susceptibility profiles of 6741 bacterial and 222 fungal pathogens causing BSI in 16 medical centers from 2012 to 2017. These results were stratified according to patient age, intensive care unit (ICU) location, and hospital onset (HO) versus community onset (CO) of infection. The leading pathogen isolated from patients in all age groups (range, 20.3–32.5%), except for those >64 years old (19.9%), was Staphylococcus aureus. Escherichia coli was the most common agent in patients over 64 years of age (26.7%). S. aureus was frequently recovered from patients with HO or CO BSI (20.9–24.1%). However, E. coli was the most commonly isolated species (24.5%) from CO infections. BSIs caused by vancomycin-resistant enterococci, penicillin-nonsusceptible S. pneumoniae, extended-spectrum β-lactamase–producing Klebsiella spp., carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa were more common among patients in ICUs compared to patients hospitalized in a non-ICU setting. The frequency of methicillin-resistant S. aureus (MRSA) was slightly higher in the non-ICU population (37.5%) compared with the ICU group (34.1%). A trend toward a decrease in BSIs due to Gram-positive cocci and an increase in infections with Gram-negative bacilli were observed. Overall, the frequency of resistant phenotypes was high for S. aureus (MRSA; 37.0%), enterococci (vancomycin-resistant enterococci; 24.6%), Klebsiella spp. (extended-spectrum β-lactamase phenotype; 21.5%), and P. aeruginosa (multidrug-resistant; 15.4%) and generally declined from 2012 to 2017, whereas the frequency of penicillin-nonsusceptible Streptococcus pneumoniae (3.4%) and carbapenem-resistant Enterobacteriaceae (1.5%) was low overall and both resistant phenotypes declined over time. Fluconazole-resistant Candida spp. isolates were only detected in years 2013–2015.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Carvalhaes, Cecilia G.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Smith, Caitlin J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Diekema, Daniel J.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Castanheira, Mariana</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier Science</subfield><subfield code="a">Rodrigues, Jéssica S. ELSEVIER</subfield><subfield code="t">Selected Kraft lignin fractions as precursor for carbon foam: Structure-performance correlation and electrochemical applications</subfield><subfield code="d">2023</subfield><subfield code="g">Amsterdam [u.a.]</subfield><subfield code="w">(DE-627)ELV009877355</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:97</subfield><subfield code="g">year:2020</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.diagmicrobio.2020.115016</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">FID-BIODIV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">35.80</subfield><subfield code="j">Makromolekulare Chemie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.30</subfield><subfield code="j">Biotechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">97</subfield><subfield code="j">2020</subfield><subfield code="e">2</subfield><subfield code="h">0</subfield></datafield></record></collection>
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Bacterial and fungal pathogens isolated from patients with bloodstream infection: frequency of occurrence and antimicrobial susceptibility patterns from the SENTRY Antimicrobial Surveillance Program (2012–2017)

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