TLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis

• Rosacea epidermis show high HSD11B1 expression. • TLR3 agonist Poly(I:C) increases HSD11B1 expression in human epidermal keratinocytes. • Differentiated keratinocytes augments glucocorticoid synthetases induction by Poly(I:C). • The knockdown of TLR3 suppress the by Poly(I:C) stimuli. • TLR3 trans...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Shimada-Omori, Ryoko [verfasserIn]

Yamasaki, Kenshi

Koike, Saaya

Yamauchi, Takeshi

Aiba, Setsuya

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2020

Schlagwörter:

UVB

PBS

BCA

RT

SDS

NHEK

RNA

DTT

MOI

DAPI

EDTA

PVDF

PBS-T

HKGS

Ct

BSA

TBS-T

BPE

cDNA

TLR

GAPDH

PCR

PFU

Umfang:

9

Übergeordnetes Werk:

Enthalten in: Acceptability of a smartphone application with prenatal care at a federally qualified health center - Vani, Kavita ELSEVIER, 2022, the official journal of the Japanese Society for Investigative Dermatology, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:100 ; year:2020 ; number:1 ; pages:58-66 ; extent:9

Links:

Volltext

DOI / URN:

10.1016/j.jdermsci.2020.08.011

Katalog-ID:

ELV052496333

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