Menin-MLL inhibitor blocks progression of middle ear cholesteatoma in vivo

Cholesteatoma is an epithelial lesion that expands into the middle ear, resulting in bone destruction. The acceleration of the proliferative activity of epithelial stem/progenitor cells is involved in the pathogenesis of cholesteatoma. Recently, the use of a menin-mixed lineage leukemia 1 (MLL1) inh...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Yamamoto-Fukuda, Tomomi [verfasserIn]

Akiyama, Naotaro

Tatsumi, Norifumi

Okabe, Masataka

Kojima, Hiromi

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2021

Schlagwörter:

Cholesteatoma

Level of evidence: N/A

KGF

p63

Menin-MLL inhibitor

Übergeordnetes Werk:

Enthalten in: Investigation of structural analogs of hydroxychloroquine for SARS-CoV-2 main protease (Mpro): A computational drug discovery study - Reyaz, Saima ELSEVIER, 2021, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:140 ; year:2021 ; pages:0

Links:

Volltext

DOI / URN:

10.1016/j.ijporl.2020.110545

Katalog-ID:

ELV052536254

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