Baseline effector cells predict response and NKT cells predict pulmonary toxicity in advanced breast cancer patients treated with everolimus and exemestane

• We describe prospective immunomonitoring of BC patients on everolimus exemestane. • The baseline percentage of CD4+ effector cells was predictive of non-response. • The baseline percentage of NKT-cells was predictive of pulmonary toxicity.

Gespeichert in:
Autor*in:

Willemsen, Annelieke E.C.A.B. [verfasserIn]

He, Xuehui

van Cranenbroek, Bram

de Jong, Paul C.

de Boer, Maaike

Joosten, Irma

Koenen, Hans J.P.M.

van Herpen, Carla M.L.

Gerritsen, Winald R.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2021

Schlagwörter:

Drug-induced lung injury

Interstitial lung disease

Everolimus

Immunomonitoring

Response prediction

Übergeordnetes Werk:

Enthalten in: International immunopharmacology - Laupland, Kevin B. ELSEVIER, 2022, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:93 ; year:2021 ; pages:0

Links:

Volltext

DOI / URN:

10.1016/j.intimp.2021.107404

Katalog-ID:

ELV053323076

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