Finding predictive factors for immunotherapy in metastatic renal-cell carcinoma: What are we looking for?
• Immune-based combinations have led to marked improvements in OS in mRCC. • One major challenges is to identify a predictive biomarker of response to immunotherapy-based treatments in mRCC. • Anticancer immune response is extremely complex, thus finding a unique biomarker for patient’s selection ma...
Ausführliche Beschreibung
Autor*in: |
Guida, Annalisa [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Using regression analysis to predict the future energy consumption of a supermarket in the UK - Braun, M.R. ELSEVIER, 2014, Amsterdam [u.a.] |
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Übergeordnetes Werk: |
volume:94 ; year:2021 ; pages:0 |
Links: |
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DOI / URN: |
10.1016/j.ctrv.2021.102157 |
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ELV053460871 |
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10.1016/j.ctrv.2021.102157 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001418.pica (DE-627)ELV053460871 (ELSEVIER)S0305-7372(21)00005-0 DE-627 ger DE-627 rakwb eng 620 VZ 150 300 VZ 77.52 bkl Guida, Annalisa verfasserin aut Finding predictive factors for immunotherapy in metastatic renal-cell carcinoma: What are we looking for? 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Immune-based combinations have led to marked improvements in OS in mRCC. • One major challenges is to identify a predictive biomarker of response to immunotherapy-based treatments in mRCC. • Anticancer immune response is extremely complex, thus finding a unique biomarker for patient’s selection may not be feasible. • The development of a reproducible and reliable biomarker will require the integration of different elements, e.g. checkpoints’ expression, TILs, mutational load, and probably many others emergent biological events. Metastatic clear-cell renal cell carcinoma Elsevier Predictive factors Elsevier Immunotherapy Elsevier Biomarkers Elsevier Sabbatini, Roberto oth Gibellini, Lara oth De Biasi, Sara oth Cossarizza, Andrea oth Porta, Camillo oth Enthalten in Elsevier Braun, M.R. ELSEVIER Using regression analysis to predict the future energy consumption of a supermarket in the UK 2014 Amsterdam [u.a.] (DE-627)ELV01225004X volume:94 year:2021 pages:0 https://doi.org/10.1016/j.ctrv.2021.102157 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 77.52 Differentielle Psychologie VZ AR 94 2021 0 |
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Finding predictive factors for immunotherapy in metastatic renal-cell carcinoma: What are we looking for? |
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• Immune-based combinations have led to marked improvements in OS in mRCC. • One major challenges is to identify a predictive biomarker of response to immunotherapy-based treatments in mRCC. • Anticancer immune response is extremely complex, thus finding a unique biomarker for patient’s selection may not be feasible. • The development of a reproducible and reliable biomarker will require the integration of different elements, e.g. checkpoints’ expression, TILs, mutational load, and probably many others emergent biological events. |
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• Immune-based combinations have led to marked improvements in OS in mRCC. • One major challenges is to identify a predictive biomarker of response to immunotherapy-based treatments in mRCC. • Anticancer immune response is extremely complex, thus finding a unique biomarker for patient’s selection may not be feasible. • The development of a reproducible and reliable biomarker will require the integration of different elements, e.g. checkpoints’ expression, TILs, mutational load, and probably many others emergent biological events. |
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• Immune-based combinations have led to marked improvements in OS in mRCC. • One major challenges is to identify a predictive biomarker of response to immunotherapy-based treatments in mRCC. • Anticancer immune response is extremely complex, thus finding a unique biomarker for patient’s selection may not be feasible. • The development of a reproducible and reliable biomarker will require the integration of different elements, e.g. checkpoints’ expression, TILs, mutational load, and probably many others emergent biological events. |
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