Differential levels of IFNα subtypes in autoimmunity and viral infection
• Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 p...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Bondet, Vincent [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types - McLaughlin, Richard J. ELSEVIER, 2022, the official journal of the International Cytokine Society, Oxford [u.a.] |
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| Übergeordnetes Werk: |
volume:144 ; year:2021 ; pages:0 |
| Links: |
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| DOI / URN: |
10.1016/j.cyto.2021.155533 |
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| 520 | |a • Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. | ||
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10.1016/j.cyto.2021.155533 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001423.pica (DE-627)ELV054251893 (ELSEVIER)S1043-4666(21)00113-7 DE-627 ger DE-627 rakwb eng 610 VZ 44.83 bkl Bondet, Vincent verfasserin aut Differential levels of IFNα subtypes in autoimmunity and viral infection 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. Autoimmunity Elsevier Anti-IFNα autoantibodies Elsevier IFNα subtypes Elsevier IFN function Elsevier Viral infection Elsevier TLR activation Elsevier Rodero, Mathieu P. oth Posseme, Céline oth Bost, Pierre oth Decalf, Jérémie oth Haljasmägi, Liis oth Bekaddour, Nassima oth Rice, Gillian I. oth Upasani, Vinit oth Herbeuval, Jean-Philippe oth Reynolds, John A. oth Briggs, Tracy A. oth Bruce, Ian N. oth Mauri, Claudia oth Isenberg, David oth Menon, Madhvi oth Hunt, David oth Schwikowski, Benno oth Mariette, Xavier oth Pol, Stanislas oth Rozenberg, Flore oth Cantaert, Tineke oth Eric Gottenberg, J. oth Kisand, Kai oth Duffy, Darragh oth Enthalten in Elsevier McLaughlin, Richard J. ELSEVIER The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types 2022 the official journal of the International Cytokine Society Oxford [u.a.] (DE-627)ELV008219540 volume:144 year:2021 pages:0 https://doi.org/10.1016/j.cyto.2021.155533 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.83 Rheumatologie Orthopädie VZ AR 144 2021 0 |
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10.1016/j.cyto.2021.155533 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001423.pica (DE-627)ELV054251893 (ELSEVIER)S1043-4666(21)00113-7 DE-627 ger DE-627 rakwb eng 610 VZ 44.83 bkl Bondet, Vincent verfasserin aut Differential levels of IFNα subtypes in autoimmunity and viral infection 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. Autoimmunity Elsevier Anti-IFNα autoantibodies Elsevier IFNα subtypes Elsevier IFN function Elsevier Viral infection Elsevier TLR activation Elsevier Rodero, Mathieu P. oth Posseme, Céline oth Bost, Pierre oth Decalf, Jérémie oth Haljasmägi, Liis oth Bekaddour, Nassima oth Rice, Gillian I. oth Upasani, Vinit oth Herbeuval, Jean-Philippe oth Reynolds, John A. oth Briggs, Tracy A. oth Bruce, Ian N. oth Mauri, Claudia oth Isenberg, David oth Menon, Madhvi oth Hunt, David oth Schwikowski, Benno oth Mariette, Xavier oth Pol, Stanislas oth Rozenberg, Flore oth Cantaert, Tineke oth Eric Gottenberg, J. oth Kisand, Kai oth Duffy, Darragh oth Enthalten in Elsevier McLaughlin, Richard J. ELSEVIER The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types 2022 the official journal of the International Cytokine Society Oxford [u.a.] (DE-627)ELV008219540 volume:144 year:2021 pages:0 https://doi.org/10.1016/j.cyto.2021.155533 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.83 Rheumatologie Orthopädie VZ AR 144 2021 0 |
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10.1016/j.cyto.2021.155533 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001423.pica (DE-627)ELV054251893 (ELSEVIER)S1043-4666(21)00113-7 DE-627 ger DE-627 rakwb eng 610 VZ 44.83 bkl Bondet, Vincent verfasserin aut Differential levels of IFNα subtypes in autoimmunity and viral infection 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. Autoimmunity Elsevier Anti-IFNα autoantibodies Elsevier IFNα subtypes Elsevier IFN function Elsevier Viral infection Elsevier TLR activation Elsevier Rodero, Mathieu P. oth Posseme, Céline oth Bost, Pierre oth Decalf, Jérémie oth Haljasmägi, Liis oth Bekaddour, Nassima oth Rice, Gillian I. oth Upasani, Vinit oth Herbeuval, Jean-Philippe oth Reynolds, John A. oth Briggs, Tracy A. oth Bruce, Ian N. oth Mauri, Claudia oth Isenberg, David oth Menon, Madhvi oth Hunt, David oth Schwikowski, Benno oth Mariette, Xavier oth Pol, Stanislas oth Rozenberg, Flore oth Cantaert, Tineke oth Eric Gottenberg, J. oth Kisand, Kai oth Duffy, Darragh oth Enthalten in Elsevier McLaughlin, Richard J. ELSEVIER The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types 2022 the official journal of the International Cytokine Society Oxford [u.a.] (DE-627)ELV008219540 volume:144 year:2021 pages:0 https://doi.org/10.1016/j.cyto.2021.155533 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.83 Rheumatologie Orthopädie VZ AR 144 2021 0 |
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10.1016/j.cyto.2021.155533 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001423.pica (DE-627)ELV054251893 (ELSEVIER)S1043-4666(21)00113-7 DE-627 ger DE-627 rakwb eng 610 VZ 44.83 bkl Bondet, Vincent verfasserin aut Differential levels of IFNα subtypes in autoimmunity and viral infection 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. Autoimmunity Elsevier Anti-IFNα autoantibodies Elsevier IFNα subtypes Elsevier IFN function Elsevier Viral infection Elsevier TLR activation Elsevier Rodero, Mathieu P. oth Posseme, Céline oth Bost, Pierre oth Decalf, Jérémie oth Haljasmägi, Liis oth Bekaddour, Nassima oth Rice, Gillian I. oth Upasani, Vinit oth Herbeuval, Jean-Philippe oth Reynolds, John A. oth Briggs, Tracy A. oth Bruce, Ian N. oth Mauri, Claudia oth Isenberg, David oth Menon, Madhvi oth Hunt, David oth Schwikowski, Benno oth Mariette, Xavier oth Pol, Stanislas oth Rozenberg, Flore oth Cantaert, Tineke oth Eric Gottenberg, J. oth Kisand, Kai oth Duffy, Darragh oth Enthalten in Elsevier McLaughlin, Richard J. ELSEVIER The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types 2022 the official journal of the International Cytokine Society Oxford [u.a.] (DE-627)ELV008219540 volume:144 year:2021 pages:0 https://doi.org/10.1016/j.cyto.2021.155533 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.83 Rheumatologie Orthopädie VZ AR 144 2021 0 |
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10.1016/j.cyto.2021.155533 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001423.pica (DE-627)ELV054251893 (ELSEVIER)S1043-4666(21)00113-7 DE-627 ger DE-627 rakwb eng 610 VZ 44.83 bkl Bondet, Vincent verfasserin aut Differential levels of IFNα subtypes in autoimmunity and viral infection 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. Autoimmunity Elsevier Anti-IFNα autoantibodies Elsevier IFNα subtypes Elsevier IFN function Elsevier Viral infection Elsevier TLR activation Elsevier Rodero, Mathieu P. oth Posseme, Céline oth Bost, Pierre oth Decalf, Jérémie oth Haljasmägi, Liis oth Bekaddour, Nassima oth Rice, Gillian I. oth Upasani, Vinit oth Herbeuval, Jean-Philippe oth Reynolds, John A. oth Briggs, Tracy A. oth Bruce, Ian N. oth Mauri, Claudia oth Isenberg, David oth Menon, Madhvi oth Hunt, David oth Schwikowski, Benno oth Mariette, Xavier oth Pol, Stanislas oth Rozenberg, Flore oth Cantaert, Tineke oth Eric Gottenberg, J. oth Kisand, Kai oth Duffy, Darragh oth Enthalten in Elsevier McLaughlin, Richard J. ELSEVIER The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types 2022 the official journal of the International Cytokine Society Oxford [u.a.] (DE-627)ELV008219540 volume:144 year:2021 pages:0 https://doi.org/10.1016/j.cyto.2021.155533 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.83 Rheumatologie Orthopädie VZ AR 144 2021 0 |
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Enthalten in The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types Oxford [u.a.] volume:144 year:2021 pages:0 |
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Autoimmunity Anti-IFNα autoantibodies IFNα subtypes IFN function Viral infection TLR activation |
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The minimal clinically important differences of the Simple Shoulder Test are different for different arthroplasty types |
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Bondet, Vincent @@aut@@ Rodero, Mathieu P. @@oth@@ Posseme, Céline @@oth@@ Bost, Pierre @@oth@@ Decalf, Jérémie @@oth@@ Haljasmägi, Liis @@oth@@ Bekaddour, Nassima @@oth@@ Rice, Gillian I. @@oth@@ Upasani, Vinit @@oth@@ Herbeuval, Jean-Philippe @@oth@@ Reynolds, John A. @@oth@@ Briggs, Tracy A. @@oth@@ Bruce, Ian N. @@oth@@ Mauri, Claudia @@oth@@ Isenberg, David @@oth@@ Menon, Madhvi @@oth@@ Hunt, David @@oth@@ Schwikowski, Benno @@oth@@ Mariette, Xavier @@oth@@ Pol, Stanislas @@oth@@ Rozenberg, Flore @@oth@@ Cantaert, Tineke @@oth@@ Eric Gottenberg, J. @@oth@@ Kisand, Kai @@oth@@ Duffy, Darragh @@oth@@ |
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Differential levels of IFNα subtypes in autoimmunity and viral infection |
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• Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. |
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• Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. |
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• Development of digital ELISA with high attomolar sensitivity for the IFNα2 subtype. • Identified different IFNα subtype ratios in viral infection and autoimmune patients. • Subgroup of autoimmune patients had high IFNα2 but low pan-IFNα protein measurements. • In this sub group of patients IFNα2 protein did not reflect its biological activity. • Phenotype was partly explained by anti-IFNα auto-antibodies in a subset of patients. |
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