Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study
Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Win, Aung Ko [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021 |
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| Umfang: |
9 |
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| Übergeordnetes Werk: |
Enthalten in: My - Citovsky, Vitaly ELSEVIER, 2019, London |
|---|---|
| Übergeordnetes Werk: |
volume:22 ; year:2021 ; number:7 ; pages:1014-1022 ; extent:9 |
| Links: |
|---|
| DOI / URN: |
10.1016/S1470-2045(21)00189-3 |
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| Katalog-ID: |
ELV054513367 |
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| 245 | 1 | 0 | |a Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study |
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| 520 | |a Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. | ||
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10.1016/S1470-2045(21)00189-3 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001579.pica (DE-627)ELV054513367 (ELSEVIER)S1470-2045(21)00189-3 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Win, Aung Ko verfasserin aut Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study 2021 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. Dowty, James G. oth Reece, Jeanette C. oth Lee, Grant oth Templeton, Allyson S. oth Plazzer, John-Paul oth Buchanan, Daniel D. oth Akagi, Kiwamu oth Aksoy, Seçil oth Alonso, Angel oth Alvarez, Karin oth Amor, David J. oth Ankathil, Ravindran oth Aretz, Stefan oth Arnold, Julie L. oth Aronson, Melyssa oth Austin, Rachel oth Backman, Ann-Sofie oth Bajwa-ten Broeke, Sanne W. oth Barca-Tierno, Verónica oth Barwell, Julian oth Bernstein, Inge oth Berthet, Pascaline oth Betz, Beate oth Bignon, Yves-Jean oth Boisjoli, Talya oth Bonadona, Valérie oth Briollais, Laurent oth Brunet, Joan oth Bucksch, Karolin oth Buecher, Bruno oth Buettner, Reinhard oth Burn, John oth Caldés, Trinidad oth Capella, Gabriel oth Caron, Olivier oth Casey, Graham oth Chew, Min H. oth Choi, Yun-hee oth Church, James oth Clendenning, Mark oth Colas, Chrystelle oth Cops, Elisa J. oth Coupier, Isabelle oth Cruz-Correa, Marcia oth de la Chapelle, Albert oth de Wind, Niels oth Dębniak, Tadeusz oth Della Valle, Adriana oth Delnatte, Capuccine oth Dhooge, Marion oth Dominguez-Valentin, Mev oth Drouet, Youenn oth Duijkers, Floor A. oth Engel, Christoph oth Esperon, Patricia oth Evans, D. Gareth oth Falcón de Vargas, Aída oth Figueiredo, Jane C oth Foulkes, William oth Fourme, Emmanuelle oth Frebourg, Thierry oth Gallinger, Steven oth Garre, Pilar oth Genuardi, Maurizio oth Gerdes, Anne-Marie oth Gima, Lauren M. oth Giraud, Sophie oth Goodwin, Annabel oth Görgens, Heike oth Green, Kate oth Guillem, Jose oth Guillén-Ponce, Carmen oth Guimbaud, Roselyne oth Guindalini, Rodrigo S.C. oth Half, Elizabeth E. oth Hall, Michael J oth Hampel, Heather oth Hansen, Thomas V.O. oth Heinimann, Karl oth Hes, Frederik J. oth Hill, James oth Ho, Judy W.C. oth Holinski-Feder, Elke oth Hoogerbrugge, Nicoline oth Hüneburg, Robert oth Huntley, Vanessa oth James, Paul A. oth Jensen, Uffe B oth John, Thomas oth Juhari, Wan K.W. oth Kalady, Matthew oth Kastrinos, Fay oth Kloor, Matthias oth Kohonen-Corish, Maija RJ oth Krogh, Lotte N. oth Kupfer, Sonia S. oth Ladabaum, Uri oth Lagerstedt-Robinson, Kristina oth Lalloo, Fiona oth Lasset, Christine oth Latchford, Andrew oth Laurent-Puig, Pierre oth Lautrup, Charlotte K. oth Leggett, Barbara A. oth Lejeune, Sophie oth LeMarchand, Loic oth Ligtenberg, Marjolijn oth Lindor, Noralane oth Loeffler, Markus oth Longy, Michel oth Lopez, Francisco oth Lowery, Jan oth Lubiński, Jan oth Lucassen, Anneke M oth Lynch, Patrick M. oth Malińska, Karolina oth Matsubara, Nagahide oth Mecklin, Jukka-Pekka oth Møller, Pål oth Monahan, Kevin oth Morrison, Patrick J. oth Nattermann, Jacob oth Navarro, Matilde oth Neffa, Florencia oth Neklason, Deborah oth Newcomb, Polly A. oth Ngeow, Joanne oth Nichols, Cassandra oth Nielsen, Maartje oth Nixon, Dawn M. oth Nogues, Catherine oth Okkels, Henrik oth Olschwang, Sylviane oth Pachter, Nicholas oth Pai, Rish K. oth Palmero, Edenir I. oth Pande, Mala oth Parry, Susan oth Patel, Swati G. oth Pearlman, Rachel oth Perne, Claudia oth Pineda, Marta oth Poplawski, Nicola K oth Pylvänäinen, Kirsi oth Qiu, Jay oth Rahner, Nils oth Ramesar, Raj oth Rasmussen, Lene J. oth Redler, Silke oth Reis, Rui M. oth Ricciardiello, Luigi oth Rogoża-Janiszewska, Emilia oth Rosty, Christophe oth Samadder, N. Jewel oth Sampson, Julian R. oth Schackert, Hans K. oth Schmiegel, Wolff oth Schulmann, Karsten oth Schuster, Helène oth Scott, Rodney oth Senter, Leigha oth Seppälä, Toni T oth Shtoyerman, Rakefet oth Sijmons, Rolf H. oth Snyder, Carrie oth Solomon, Ilana B. oth Soto, Jose Luis oth Southey, Melissa C. oth Spigelman, Allan oth Spirandelli, Florencia oth Spurdle, Amanda B. oth Steinke-Lange, Verena oth Stoffel, Elena M. oth Strassburg, Christian P. oth Sunde, Lone oth Susman, Rachel oth Syngal, Sapna oth Tanakaya, Kohji oth Tezcan, Gülçin oth Therkildsen, Christina oth Thibodeau, Steve oth Tomita, Naohiro oth Tucker, Katherine M. oth Tunca, Berrin oth Turchetti, Daniela oth Uhrhammer, Nancy oth Utsunomiya, Joji oth Vaccaro, Carlos oth van Duijnhoven, Fränzel J.B. oth van Wanzeele, Meghan J. oth Vangala, Deepak B. oth Vasen, Hans F.A. oth von Knebel Doeberitz, Magnus oth von Salomé, Jenny oth Wadt, Karin A.W. oth Ward, Robyn L. oth Weitz, Jürgen oth Weitzel, Jeffrey N. oth Williams, Heinric oth Winship, Ingrid oth Wise, Paul E. oth Wods, Julie oth Woods, Michael O. oth Yamaguchi, Tatsuro oth Zachariae, Silke oth Zahary, Mohd N. oth Hopper, John L. oth Haile, Robert W. oth Macrae, Finlay A. oth Möslein, Gabriela oth Jenkins, Mark A. oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:22 year:2021 number:7 pages:1014-1022 extent:9 https://doi.org/10.1016/S1470-2045(21)00189-3 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 22 2021 7 1014-1022 9 |
| spelling |
10.1016/S1470-2045(21)00189-3 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001579.pica (DE-627)ELV054513367 (ELSEVIER)S1470-2045(21)00189-3 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Win, Aung Ko verfasserin aut Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study 2021 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. Dowty, James G. oth Reece, Jeanette C. oth Lee, Grant oth Templeton, Allyson S. oth Plazzer, John-Paul oth Buchanan, Daniel D. oth Akagi, Kiwamu oth Aksoy, Seçil oth Alonso, Angel oth Alvarez, Karin oth Amor, David J. oth Ankathil, Ravindran oth Aretz, Stefan oth Arnold, Julie L. oth Aronson, Melyssa oth Austin, Rachel oth Backman, Ann-Sofie oth Bajwa-ten Broeke, Sanne W. oth Barca-Tierno, Verónica oth Barwell, Julian oth Bernstein, Inge oth Berthet, Pascaline oth Betz, Beate oth Bignon, Yves-Jean oth Boisjoli, Talya oth Bonadona, Valérie oth Briollais, Laurent oth Brunet, Joan oth Bucksch, Karolin oth Buecher, Bruno oth Buettner, Reinhard oth Burn, John oth Caldés, Trinidad oth Capella, Gabriel oth Caron, Olivier oth Casey, Graham oth Chew, Min H. oth Choi, Yun-hee oth Church, James oth Clendenning, Mark oth Colas, Chrystelle oth Cops, Elisa J. oth Coupier, Isabelle oth Cruz-Correa, Marcia oth de la Chapelle, Albert oth de Wind, Niels oth Dębniak, Tadeusz oth Della Valle, Adriana oth Delnatte, Capuccine oth Dhooge, Marion oth Dominguez-Valentin, Mev oth Drouet, Youenn oth Duijkers, Floor A. oth Engel, Christoph oth Esperon, Patricia oth Evans, D. Gareth oth Falcón de Vargas, Aída oth Figueiredo, Jane C oth Foulkes, William oth Fourme, Emmanuelle oth Frebourg, Thierry oth Gallinger, Steven oth Garre, Pilar oth Genuardi, Maurizio oth Gerdes, Anne-Marie oth Gima, Lauren M. oth Giraud, Sophie oth Goodwin, Annabel oth Görgens, Heike oth Green, Kate oth Guillem, Jose oth Guillén-Ponce, Carmen oth Guimbaud, Roselyne oth Guindalini, Rodrigo S.C. oth Half, Elizabeth E. oth Hall, Michael J oth Hampel, Heather oth Hansen, Thomas V.O. oth Heinimann, Karl oth Hes, Frederik J. oth Hill, James oth Ho, Judy W.C. oth Holinski-Feder, Elke oth Hoogerbrugge, Nicoline oth Hüneburg, Robert oth Huntley, Vanessa oth James, Paul A. oth Jensen, Uffe B oth John, Thomas oth Juhari, Wan K.W. oth Kalady, Matthew oth Kastrinos, Fay oth Kloor, Matthias oth Kohonen-Corish, Maija RJ oth Krogh, Lotte N. oth Kupfer, Sonia S. oth Ladabaum, Uri oth Lagerstedt-Robinson, Kristina oth Lalloo, Fiona oth Lasset, Christine oth Latchford, Andrew oth Laurent-Puig, Pierre oth Lautrup, Charlotte K. oth Leggett, Barbara A. oth Lejeune, Sophie oth LeMarchand, Loic oth Ligtenberg, Marjolijn oth Lindor, Noralane oth Loeffler, Markus oth Longy, Michel oth Lopez, Francisco oth Lowery, Jan oth Lubiński, Jan oth Lucassen, Anneke M oth Lynch, Patrick M. oth Malińska, Karolina oth Matsubara, Nagahide oth Mecklin, Jukka-Pekka oth Møller, Pål oth Monahan, Kevin oth Morrison, Patrick J. oth Nattermann, Jacob oth Navarro, Matilde oth Neffa, Florencia oth Neklason, Deborah oth Newcomb, Polly A. oth Ngeow, Joanne oth Nichols, Cassandra oth Nielsen, Maartje oth Nixon, Dawn M. oth Nogues, Catherine oth Okkels, Henrik oth Olschwang, Sylviane oth Pachter, Nicholas oth Pai, Rish K. oth Palmero, Edenir I. oth Pande, Mala oth Parry, Susan oth Patel, Swati G. oth Pearlman, Rachel oth Perne, Claudia oth Pineda, Marta oth Poplawski, Nicola K oth Pylvänäinen, Kirsi oth Qiu, Jay oth Rahner, Nils oth Ramesar, Raj oth Rasmussen, Lene J. oth Redler, Silke oth Reis, Rui M. oth Ricciardiello, Luigi oth Rogoża-Janiszewska, Emilia oth Rosty, Christophe oth Samadder, N. Jewel oth Sampson, Julian R. oth Schackert, Hans K. oth Schmiegel, Wolff oth Schulmann, Karsten oth Schuster, Helène oth Scott, Rodney oth Senter, Leigha oth Seppälä, Toni T oth Shtoyerman, Rakefet oth Sijmons, Rolf H. oth Snyder, Carrie oth Solomon, Ilana B. oth Soto, Jose Luis oth Southey, Melissa C. oth Spigelman, Allan oth Spirandelli, Florencia oth Spurdle, Amanda B. oth Steinke-Lange, Verena oth Stoffel, Elena M. oth Strassburg, Christian P. oth Sunde, Lone oth Susman, Rachel oth Syngal, Sapna oth Tanakaya, Kohji oth Tezcan, Gülçin oth Therkildsen, Christina oth Thibodeau, Steve oth Tomita, Naohiro oth Tucker, Katherine M. oth Tunca, Berrin oth Turchetti, Daniela oth Uhrhammer, Nancy oth Utsunomiya, Joji oth Vaccaro, Carlos oth van Duijnhoven, Fränzel J.B. oth van Wanzeele, Meghan J. oth Vangala, Deepak B. oth Vasen, Hans F.A. oth von Knebel Doeberitz, Magnus oth von Salomé, Jenny oth Wadt, Karin A.W. oth Ward, Robyn L. oth Weitz, Jürgen oth Weitzel, Jeffrey N. oth Williams, Heinric oth Winship, Ingrid oth Wise, Paul E. oth Wods, Julie oth Woods, Michael O. oth Yamaguchi, Tatsuro oth Zachariae, Silke oth Zahary, Mohd N. oth Hopper, John L. oth Haile, Robert W. oth Macrae, Finlay A. oth Möslein, Gabriela oth Jenkins, Mark A. oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:22 year:2021 number:7 pages:1014-1022 extent:9 https://doi.org/10.1016/S1470-2045(21)00189-3 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 22 2021 7 1014-1022 9 |
| allfields_unstemmed |
10.1016/S1470-2045(21)00189-3 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001579.pica (DE-627)ELV054513367 (ELSEVIER)S1470-2045(21)00189-3 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Win, Aung Ko verfasserin aut Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study 2021 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. Dowty, James G. oth Reece, Jeanette C. oth Lee, Grant oth Templeton, Allyson S. oth Plazzer, John-Paul oth Buchanan, Daniel D. oth Akagi, Kiwamu oth Aksoy, Seçil oth Alonso, Angel oth Alvarez, Karin oth Amor, David J. oth Ankathil, Ravindran oth Aretz, Stefan oth Arnold, Julie L. oth Aronson, Melyssa oth Austin, Rachel oth Backman, Ann-Sofie oth Bajwa-ten Broeke, Sanne W. oth Barca-Tierno, Verónica oth Barwell, Julian oth Bernstein, Inge oth Berthet, Pascaline oth Betz, Beate oth Bignon, Yves-Jean oth Boisjoli, Talya oth Bonadona, Valérie oth Briollais, Laurent oth Brunet, Joan oth Bucksch, Karolin oth Buecher, Bruno oth Buettner, Reinhard oth Burn, John oth Caldés, Trinidad oth Capella, Gabriel oth Caron, Olivier oth Casey, Graham oth Chew, Min H. oth Choi, Yun-hee oth Church, James oth Clendenning, Mark oth Colas, Chrystelle oth Cops, Elisa J. oth Coupier, Isabelle oth Cruz-Correa, Marcia oth de la Chapelle, Albert oth de Wind, Niels oth Dębniak, Tadeusz oth Della Valle, Adriana oth Delnatte, Capuccine oth Dhooge, Marion oth Dominguez-Valentin, Mev oth Drouet, Youenn oth Duijkers, Floor A. oth Engel, Christoph oth Esperon, Patricia oth Evans, D. Gareth oth Falcón de Vargas, Aída oth Figueiredo, Jane C oth Foulkes, William oth Fourme, Emmanuelle oth Frebourg, Thierry oth Gallinger, Steven oth Garre, Pilar oth Genuardi, Maurizio oth Gerdes, Anne-Marie oth Gima, Lauren M. oth Giraud, Sophie oth Goodwin, Annabel oth Görgens, Heike oth Green, Kate oth Guillem, Jose oth Guillén-Ponce, Carmen oth Guimbaud, Roselyne oth Guindalini, Rodrigo S.C. oth Half, Elizabeth E. oth Hall, Michael J oth Hampel, Heather oth Hansen, Thomas V.O. oth Heinimann, Karl oth Hes, Frederik J. oth Hill, James oth Ho, Judy W.C. oth Holinski-Feder, Elke oth Hoogerbrugge, Nicoline oth Hüneburg, Robert oth Huntley, Vanessa oth James, Paul A. oth Jensen, Uffe B oth John, Thomas oth Juhari, Wan K.W. oth Kalady, Matthew oth Kastrinos, Fay oth Kloor, Matthias oth Kohonen-Corish, Maija RJ oth Krogh, Lotte N. oth Kupfer, Sonia S. oth Ladabaum, Uri oth Lagerstedt-Robinson, Kristina oth Lalloo, Fiona oth Lasset, Christine oth Latchford, Andrew oth Laurent-Puig, Pierre oth Lautrup, Charlotte K. oth Leggett, Barbara A. oth Lejeune, Sophie oth LeMarchand, Loic oth Ligtenberg, Marjolijn oth Lindor, Noralane oth Loeffler, Markus oth Longy, Michel oth Lopez, Francisco oth Lowery, Jan oth Lubiński, Jan oth Lucassen, Anneke M oth Lynch, Patrick M. oth Malińska, Karolina oth Matsubara, Nagahide oth Mecklin, Jukka-Pekka oth Møller, Pål oth Monahan, Kevin oth Morrison, Patrick J. oth Nattermann, Jacob oth Navarro, Matilde oth Neffa, Florencia oth Neklason, Deborah oth Newcomb, Polly A. oth Ngeow, Joanne oth Nichols, Cassandra oth Nielsen, Maartje oth Nixon, Dawn M. oth Nogues, Catherine oth Okkels, Henrik oth Olschwang, Sylviane oth Pachter, Nicholas oth Pai, Rish K. oth Palmero, Edenir I. oth Pande, Mala oth Parry, Susan oth Patel, Swati G. oth Pearlman, Rachel oth Perne, Claudia oth Pineda, Marta oth Poplawski, Nicola K oth Pylvänäinen, Kirsi oth Qiu, Jay oth Rahner, Nils oth Ramesar, Raj oth Rasmussen, Lene J. oth Redler, Silke oth Reis, Rui M. oth Ricciardiello, Luigi oth Rogoża-Janiszewska, Emilia oth Rosty, Christophe oth Samadder, N. Jewel oth Sampson, Julian R. oth Schackert, Hans K. oth Schmiegel, Wolff oth Schulmann, Karsten oth Schuster, Helène oth Scott, Rodney oth Senter, Leigha oth Seppälä, Toni T oth Shtoyerman, Rakefet oth Sijmons, Rolf H. oth Snyder, Carrie oth Solomon, Ilana B. oth Soto, Jose Luis oth Southey, Melissa C. oth Spigelman, Allan oth Spirandelli, Florencia oth Spurdle, Amanda B. oth Steinke-Lange, Verena oth Stoffel, Elena M. oth Strassburg, Christian P. oth Sunde, Lone oth Susman, Rachel oth Syngal, Sapna oth Tanakaya, Kohji oth Tezcan, Gülçin oth Therkildsen, Christina oth Thibodeau, Steve oth Tomita, Naohiro oth Tucker, Katherine M. oth Tunca, Berrin oth Turchetti, Daniela oth Uhrhammer, Nancy oth Utsunomiya, Joji oth Vaccaro, Carlos oth van Duijnhoven, Fränzel J.B. oth van Wanzeele, Meghan J. oth Vangala, Deepak B. oth Vasen, Hans F.A. oth von Knebel Doeberitz, Magnus oth von Salomé, Jenny oth Wadt, Karin A.W. oth Ward, Robyn L. oth Weitz, Jürgen oth Weitzel, Jeffrey N. oth Williams, Heinric oth Winship, Ingrid oth Wise, Paul E. oth Wods, Julie oth Woods, Michael O. oth Yamaguchi, Tatsuro oth Zachariae, Silke oth Zahary, Mohd N. oth Hopper, John L. oth Haile, Robert W. oth Macrae, Finlay A. oth Möslein, Gabriela oth Jenkins, Mark A. oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:22 year:2021 number:7 pages:1014-1022 extent:9 https://doi.org/10.1016/S1470-2045(21)00189-3 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 22 2021 7 1014-1022 9 |
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10.1016/S1470-2045(21)00189-3 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001579.pica (DE-627)ELV054513367 (ELSEVIER)S1470-2045(21)00189-3 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Win, Aung Ko verfasserin aut Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study 2021 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. Dowty, James G. oth Reece, Jeanette C. oth Lee, Grant oth Templeton, Allyson S. oth Plazzer, John-Paul oth Buchanan, Daniel D. oth Akagi, Kiwamu oth Aksoy, Seçil oth Alonso, Angel oth Alvarez, Karin oth Amor, David J. oth Ankathil, Ravindran oth Aretz, Stefan oth Arnold, Julie L. oth Aronson, Melyssa oth Austin, Rachel oth Backman, Ann-Sofie oth Bajwa-ten Broeke, Sanne W. oth Barca-Tierno, Verónica oth Barwell, Julian oth Bernstein, Inge oth Berthet, Pascaline oth Betz, Beate oth Bignon, Yves-Jean oth Boisjoli, Talya oth Bonadona, Valérie oth Briollais, Laurent oth Brunet, Joan oth Bucksch, Karolin oth Buecher, Bruno oth Buettner, Reinhard oth Burn, John oth Caldés, Trinidad oth Capella, Gabriel oth Caron, Olivier oth Casey, Graham oth Chew, Min H. oth Choi, Yun-hee oth Church, James oth Clendenning, Mark oth Colas, Chrystelle oth Cops, Elisa J. oth Coupier, Isabelle oth Cruz-Correa, Marcia oth de la Chapelle, Albert oth de Wind, Niels oth Dębniak, Tadeusz oth Della Valle, Adriana oth Delnatte, Capuccine oth Dhooge, Marion oth Dominguez-Valentin, Mev oth Drouet, Youenn oth Duijkers, Floor A. oth Engel, Christoph oth Esperon, Patricia oth Evans, D. Gareth oth Falcón de Vargas, Aída oth Figueiredo, Jane C oth Foulkes, William oth Fourme, Emmanuelle oth Frebourg, Thierry oth Gallinger, Steven oth Garre, Pilar oth Genuardi, Maurizio oth Gerdes, Anne-Marie oth Gima, Lauren M. oth Giraud, Sophie oth Goodwin, Annabel oth Görgens, Heike oth Green, Kate oth Guillem, Jose oth Guillén-Ponce, Carmen oth Guimbaud, Roselyne oth Guindalini, Rodrigo S.C. oth Half, Elizabeth E. oth Hall, Michael J oth Hampel, Heather oth Hansen, Thomas V.O. oth Heinimann, Karl oth Hes, Frederik J. oth Hill, James oth Ho, Judy W.C. oth Holinski-Feder, Elke oth Hoogerbrugge, Nicoline oth Hüneburg, Robert oth Huntley, Vanessa oth James, Paul A. oth Jensen, Uffe B oth John, Thomas oth Juhari, Wan K.W. oth Kalady, Matthew oth Kastrinos, Fay oth Kloor, Matthias oth Kohonen-Corish, Maija RJ oth Krogh, Lotte N. oth Kupfer, Sonia S. oth Ladabaum, Uri oth Lagerstedt-Robinson, Kristina oth Lalloo, Fiona oth Lasset, Christine oth Latchford, Andrew oth Laurent-Puig, Pierre oth Lautrup, Charlotte K. oth Leggett, Barbara A. oth Lejeune, Sophie oth LeMarchand, Loic oth Ligtenberg, Marjolijn oth Lindor, Noralane oth Loeffler, Markus oth Longy, Michel oth Lopez, Francisco oth Lowery, Jan oth Lubiński, Jan oth Lucassen, Anneke M oth Lynch, Patrick M. oth Malińska, Karolina oth Matsubara, Nagahide oth Mecklin, Jukka-Pekka oth Møller, Pål oth Monahan, Kevin oth Morrison, Patrick J. oth Nattermann, Jacob oth Navarro, Matilde oth Neffa, Florencia oth Neklason, Deborah oth Newcomb, Polly A. oth Ngeow, Joanne oth Nichols, Cassandra oth Nielsen, Maartje oth Nixon, Dawn M. oth Nogues, Catherine oth Okkels, Henrik oth Olschwang, Sylviane oth Pachter, Nicholas oth Pai, Rish K. oth Palmero, Edenir I. oth Pande, Mala oth Parry, Susan oth Patel, Swati G. oth Pearlman, Rachel oth Perne, Claudia oth Pineda, Marta oth Poplawski, Nicola K oth Pylvänäinen, Kirsi oth Qiu, Jay oth Rahner, Nils oth Ramesar, Raj oth Rasmussen, Lene J. oth Redler, Silke oth Reis, Rui M. oth Ricciardiello, Luigi oth Rogoża-Janiszewska, Emilia oth Rosty, Christophe oth Samadder, N. Jewel oth Sampson, Julian R. oth Schackert, Hans K. oth Schmiegel, Wolff oth Schulmann, Karsten oth Schuster, Helène oth Scott, Rodney oth Senter, Leigha oth Seppälä, Toni T oth Shtoyerman, Rakefet oth Sijmons, Rolf H. oth Snyder, Carrie oth Solomon, Ilana B. oth Soto, Jose Luis oth Southey, Melissa C. oth Spigelman, Allan oth Spirandelli, Florencia oth Spurdle, Amanda B. oth Steinke-Lange, Verena oth Stoffel, Elena M. oth Strassburg, Christian P. oth Sunde, Lone oth Susman, Rachel oth Syngal, Sapna oth Tanakaya, Kohji oth Tezcan, Gülçin oth Therkildsen, Christina oth Thibodeau, Steve oth Tomita, Naohiro oth Tucker, Katherine M. oth Tunca, Berrin oth Turchetti, Daniela oth Uhrhammer, Nancy oth Utsunomiya, Joji oth Vaccaro, Carlos oth van Duijnhoven, Fränzel J.B. oth van Wanzeele, Meghan J. oth Vangala, Deepak B. oth Vasen, Hans F.A. oth von Knebel Doeberitz, Magnus oth von Salomé, Jenny oth Wadt, Karin A.W. oth Ward, Robyn L. oth Weitz, Jürgen oth Weitzel, Jeffrey N. oth Williams, Heinric oth Winship, Ingrid oth Wise, Paul E. oth Wods, Julie oth Woods, Michael O. oth Yamaguchi, Tatsuro oth Zachariae, Silke oth Zahary, Mohd N. oth Hopper, John L. oth Haile, Robert W. oth Macrae, Finlay A. oth Möslein, Gabriela oth Jenkins, Mark A. oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:22 year:2021 number:7 pages:1014-1022 extent:9 https://doi.org/10.1016/S1470-2045(21)00189-3 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 22 2021 7 1014-1022 9 |
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10.1016/S1470-2045(21)00189-3 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001579.pica (DE-627)ELV054513367 (ELSEVIER)S1470-2045(21)00189-3 DE-627 ger DE-627 rakwb eng 570 VZ BIODIV DE-30 fid 35.70 bkl 42.12 bkl Win, Aung Ko verfasserin aut Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study 2021 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. Dowty, James G. oth Reece, Jeanette C. oth Lee, Grant oth Templeton, Allyson S. oth Plazzer, John-Paul oth Buchanan, Daniel D. oth Akagi, Kiwamu oth Aksoy, Seçil oth Alonso, Angel oth Alvarez, Karin oth Amor, David J. oth Ankathil, Ravindran oth Aretz, Stefan oth Arnold, Julie L. oth Aronson, Melyssa oth Austin, Rachel oth Backman, Ann-Sofie oth Bajwa-ten Broeke, Sanne W. oth Barca-Tierno, Verónica oth Barwell, Julian oth Bernstein, Inge oth Berthet, Pascaline oth Betz, Beate oth Bignon, Yves-Jean oth Boisjoli, Talya oth Bonadona, Valérie oth Briollais, Laurent oth Brunet, Joan oth Bucksch, Karolin oth Buecher, Bruno oth Buettner, Reinhard oth Burn, John oth Caldés, Trinidad oth Capella, Gabriel oth Caron, Olivier oth Casey, Graham oth Chew, Min H. oth Choi, Yun-hee oth Church, James oth Clendenning, Mark oth Colas, Chrystelle oth Cops, Elisa J. oth Coupier, Isabelle oth Cruz-Correa, Marcia oth de la Chapelle, Albert oth de Wind, Niels oth Dębniak, Tadeusz oth Della Valle, Adriana oth Delnatte, Capuccine oth Dhooge, Marion oth Dominguez-Valentin, Mev oth Drouet, Youenn oth Duijkers, Floor A. oth Engel, Christoph oth Esperon, Patricia oth Evans, D. Gareth oth Falcón de Vargas, Aída oth Figueiredo, Jane C oth Foulkes, William oth Fourme, Emmanuelle oth Frebourg, Thierry oth Gallinger, Steven oth Garre, Pilar oth Genuardi, Maurizio oth Gerdes, Anne-Marie oth Gima, Lauren M. oth Giraud, Sophie oth Goodwin, Annabel oth Görgens, Heike oth Green, Kate oth Guillem, Jose oth Guillén-Ponce, Carmen oth Guimbaud, Roselyne oth Guindalini, Rodrigo S.C. oth Half, Elizabeth E. oth Hall, Michael J oth Hampel, Heather oth Hansen, Thomas V.O. oth Heinimann, Karl oth Hes, Frederik J. oth Hill, James oth Ho, Judy W.C. oth Holinski-Feder, Elke oth Hoogerbrugge, Nicoline oth Hüneburg, Robert oth Huntley, Vanessa oth James, Paul A. oth Jensen, Uffe B oth John, Thomas oth Juhari, Wan K.W. oth Kalady, Matthew oth Kastrinos, Fay oth Kloor, Matthias oth Kohonen-Corish, Maija RJ oth Krogh, Lotte N. oth Kupfer, Sonia S. oth Ladabaum, Uri oth Lagerstedt-Robinson, Kristina oth Lalloo, Fiona oth Lasset, Christine oth Latchford, Andrew oth Laurent-Puig, Pierre oth Lautrup, Charlotte K. oth Leggett, Barbara A. oth Lejeune, Sophie oth LeMarchand, Loic oth Ligtenberg, Marjolijn oth Lindor, Noralane oth Loeffler, Markus oth Longy, Michel oth Lopez, Francisco oth Lowery, Jan oth Lubiński, Jan oth Lucassen, Anneke M oth Lynch, Patrick M. oth Malińska, Karolina oth Matsubara, Nagahide oth Mecklin, Jukka-Pekka oth Møller, Pål oth Monahan, Kevin oth Morrison, Patrick J. oth Nattermann, Jacob oth Navarro, Matilde oth Neffa, Florencia oth Neklason, Deborah oth Newcomb, Polly A. oth Ngeow, Joanne oth Nichols, Cassandra oth Nielsen, Maartje oth Nixon, Dawn M. oth Nogues, Catherine oth Okkels, Henrik oth Olschwang, Sylviane oth Pachter, Nicholas oth Pai, Rish K. oth Palmero, Edenir I. oth Pande, Mala oth Parry, Susan oth Patel, Swati G. oth Pearlman, Rachel oth Perne, Claudia oth Pineda, Marta oth Poplawski, Nicola K oth Pylvänäinen, Kirsi oth Qiu, Jay oth Rahner, Nils oth Ramesar, Raj oth Rasmussen, Lene J. oth Redler, Silke oth Reis, Rui M. oth Ricciardiello, Luigi oth Rogoża-Janiszewska, Emilia oth Rosty, Christophe oth Samadder, N. Jewel oth Sampson, Julian R. oth Schackert, Hans K. oth Schmiegel, Wolff oth Schulmann, Karsten oth Schuster, Helène oth Scott, Rodney oth Senter, Leigha oth Seppälä, Toni T oth Shtoyerman, Rakefet oth Sijmons, Rolf H. oth Snyder, Carrie oth Solomon, Ilana B. oth Soto, Jose Luis oth Southey, Melissa C. oth Spigelman, Allan oth Spirandelli, Florencia oth Spurdle, Amanda B. oth Steinke-Lange, Verena oth Stoffel, Elena M. oth Strassburg, Christian P. oth Sunde, Lone oth Susman, Rachel oth Syngal, Sapna oth Tanakaya, Kohji oth Tezcan, Gülçin oth Therkildsen, Christina oth Thibodeau, Steve oth Tomita, Naohiro oth Tucker, Katherine M. oth Tunca, Berrin oth Turchetti, Daniela oth Uhrhammer, Nancy oth Utsunomiya, Joji oth Vaccaro, Carlos oth van Duijnhoven, Fränzel J.B. oth van Wanzeele, Meghan J. oth Vangala, Deepak B. oth Vasen, Hans F.A. oth von Knebel Doeberitz, Magnus oth von Salomé, Jenny oth Wadt, Karin A.W. oth Ward, Robyn L. oth Weitz, Jürgen oth Weitzel, Jeffrey N. oth Williams, Heinric oth Winship, Ingrid oth Wise, Paul E. oth Wods, Julie oth Woods, Michael O. oth Yamaguchi, Tatsuro oth Zachariae, Silke oth Zahary, Mohd N. oth Hopper, John L. oth Haile, Robert W. oth Macrae, Finlay A. oth Möslein, Gabriela oth Jenkins, Mark A. oth Enthalten in The Lancet Publ. Group Citovsky, Vitaly ELSEVIER My 2019 London (DE-627)ELV003173852 volume:22 year:2021 number:7 pages:1014-1022 extent:9 https://doi.org/10.1016/S1470-2045(21)00189-3 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-BIODIV SSG-OLC-PHA 35.70 Biochemie: Allgemeines VZ 42.12 Biophysik VZ AR 22 2021 7 1014-1022 9 |
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Win, Aung Ko @@aut@@ Dowty, James G. @@oth@@ Reece, Jeanette C. @@oth@@ Lee, Grant @@oth@@ Templeton, Allyson S. @@oth@@ Plazzer, John-Paul @@oth@@ Buchanan, Daniel D. @@oth@@ Akagi, Kiwamu @@oth@@ Aksoy, Seçil @@oth@@ Alonso, Angel @@oth@@ Alvarez, Karin @@oth@@ Amor, David J. @@oth@@ Ankathil, Ravindran @@oth@@ Aretz, Stefan @@oth@@ Arnold, Julie L. @@oth@@ Aronson, Melyssa @@oth@@ Austin, Rachel @@oth@@ Backman, Ann-Sofie @@oth@@ Bajwa-ten Broeke, Sanne W. @@oth@@ Barca-Tierno, Verónica @@oth@@ Barwell, Julian @@oth@@ Bernstein, Inge @@oth@@ Berthet, Pascaline @@oth@@ Betz, Beate @@oth@@ Bignon, Yves-Jean @@oth@@ Boisjoli, Talya @@oth@@ Bonadona, Valérie @@oth@@ Briollais, Laurent @@oth@@ Brunet, Joan @@oth@@ Bucksch, Karolin @@oth@@ Buecher, Bruno @@oth@@ Buettner, Reinhard @@oth@@ Burn, John @@oth@@ Caldés, Trinidad @@oth@@ Capella, Gabriel @@oth@@ Caron, Olivier @@oth@@ Casey, Graham @@oth@@ Chew, Min H. @@oth@@ Choi, Yun-hee @@oth@@ Church, James @@oth@@ Clendenning, Mark @@oth@@ Colas, Chrystelle @@oth@@ Cops, Elisa J. @@oth@@ Coupier, Isabelle @@oth@@ Cruz-Correa, Marcia @@oth@@ de la Chapelle, Albert @@oth@@ de Wind, Niels @@oth@@ Dębniak, Tadeusz @@oth@@ Della Valle, Adriana @@oth@@ Delnatte, Capuccine @@oth@@ Dhooge, Marion @@oth@@ Dominguez-Valentin, Mev @@oth@@ Drouet, Youenn @@oth@@ Duijkers, Floor A. @@oth@@ Engel, Christoph @@oth@@ Esperon, Patricia @@oth@@ Evans, D. Gareth @@oth@@ Falcón de Vargas, Aída @@oth@@ Figueiredo, Jane C @@oth@@ Foulkes, William @@oth@@ Fourme, Emmanuelle @@oth@@ Frebourg, Thierry @@oth@@ Gallinger, Steven @@oth@@ Garre, Pilar @@oth@@ Genuardi, Maurizio @@oth@@ Gerdes, Anne-Marie @@oth@@ Gima, Lauren M. @@oth@@ Giraud, Sophie @@oth@@ Goodwin, Annabel @@oth@@ Görgens, Heike @@oth@@ Green, Kate @@oth@@ Guillem, Jose @@oth@@ Guillén-Ponce, Carmen @@oth@@ Guimbaud, Roselyne @@oth@@ Guindalini, Rodrigo S.C. @@oth@@ Half, Elizabeth E. @@oth@@ Hall, Michael J @@oth@@ Hampel, Heather @@oth@@ Hansen, Thomas V.O. @@oth@@ Heinimann, Karl @@oth@@ Hes, Frederik J. @@oth@@ Hill, James @@oth@@ Ho, Judy W.C. @@oth@@ Holinski-Feder, Elke @@oth@@ Hoogerbrugge, Nicoline @@oth@@ Hüneburg, Robert @@oth@@ Huntley, Vanessa @@oth@@ James, Paul A. @@oth@@ Jensen, Uffe B @@oth@@ John, Thomas @@oth@@ Juhari, Wan K.W. @@oth@@ Kalady, Matthew @@oth@@ Kastrinos, Fay @@oth@@ Kloor, Matthias @@oth@@ Kohonen-Corish, Maija RJ @@oth@@ Krogh, Lotte N. @@oth@@ Kupfer, Sonia S. @@oth@@ Ladabaum, Uri @@oth@@ Lagerstedt-Robinson, Kristina @@oth@@ Lalloo, Fiona @@oth@@ Lasset, Christine @@oth@@ Latchford, Andrew @@oth@@ Laurent-Puig, Pierre @@oth@@ Lautrup, Charlotte K. @@oth@@ Leggett, Barbara A. @@oth@@ Lejeune, Sophie @@oth@@ LeMarchand, Loic @@oth@@ Ligtenberg, Marjolijn @@oth@@ Lindor, Noralane @@oth@@ Loeffler, Markus @@oth@@ Longy, Michel @@oth@@ Lopez, Francisco @@oth@@ Lowery, Jan @@oth@@ Lubiński, Jan @@oth@@ Lucassen, Anneke M @@oth@@ Lynch, Patrick M. @@oth@@ Malińska, Karolina @@oth@@ Matsubara, Nagahide @@oth@@ Mecklin, Jukka-Pekka @@oth@@ Møller, Pål @@oth@@ Monahan, Kevin @@oth@@ Morrison, Patrick J. @@oth@@ Nattermann, Jacob @@oth@@ Navarro, Matilde @@oth@@ Neffa, Florencia @@oth@@ Neklason, Deborah @@oth@@ Newcomb, Polly A. @@oth@@ Ngeow, Joanne @@oth@@ Nichols, Cassandra @@oth@@ Nielsen, Maartje @@oth@@ Nixon, Dawn M. @@oth@@ Nogues, Catherine @@oth@@ Okkels, Henrik @@oth@@ Olschwang, Sylviane @@oth@@ Pachter, Nicholas @@oth@@ Pai, Rish K. @@oth@@ Palmero, Edenir I. @@oth@@ Pande, Mala @@oth@@ Parry, Susan @@oth@@ Patel, Swati G. @@oth@@ Pearlman, Rachel @@oth@@ Perne, Claudia @@oth@@ Pineda, Marta @@oth@@ Poplawski, Nicola K @@oth@@ Pylvänäinen, Kirsi @@oth@@ Qiu, Jay @@oth@@ Rahner, Nils @@oth@@ Ramesar, Raj @@oth@@ Rasmussen, Lene J. @@oth@@ Redler, Silke @@oth@@ Reis, Rui M. @@oth@@ Ricciardiello, Luigi @@oth@@ Rogoża-Janiszewska, Emilia @@oth@@ Rosty, Christophe @@oth@@ Samadder, N. Jewel @@oth@@ Sampson, Julian R. @@oth@@ Schackert, Hans K. @@oth@@ Schmiegel, Wolff @@oth@@ Schulmann, Karsten @@oth@@ Schuster, Helène @@oth@@ Scott, Rodney @@oth@@ Senter, Leigha @@oth@@ Seppälä, Toni T @@oth@@ Shtoyerman, Rakefet @@oth@@ Sijmons, Rolf H. @@oth@@ Snyder, Carrie @@oth@@ Solomon, Ilana B. @@oth@@ Soto, Jose Luis @@oth@@ Southey, Melissa C. @@oth@@ Spigelman, Allan @@oth@@ Spirandelli, Florencia @@oth@@ Spurdle, Amanda B. @@oth@@ Steinke-Lange, Verena @@oth@@ Stoffel, Elena M. @@oth@@ Strassburg, Christian P. @@oth@@ Sunde, Lone @@oth@@ Susman, Rachel @@oth@@ Syngal, Sapna @@oth@@ Tanakaya, Kohji @@oth@@ Tezcan, Gülçin @@oth@@ Therkildsen, Christina @@oth@@ Thibodeau, Steve @@oth@@ Tomita, Naohiro @@oth@@ Tucker, Katherine M. @@oth@@ Tunca, Berrin @@oth@@ Turchetti, Daniela @@oth@@ Uhrhammer, Nancy @@oth@@ Utsunomiya, Joji @@oth@@ Vaccaro, Carlos @@oth@@ van Duijnhoven, Fränzel J.B. @@oth@@ van Wanzeele, Meghan J. @@oth@@ Vangala, Deepak B. @@oth@@ Vasen, Hans F.A. @@oth@@ von Knebel Doeberitz, Magnus @@oth@@ von Salomé, Jenny @@oth@@ Wadt, Karin A.W. @@oth@@ Ward, Robyn L. @@oth@@ Weitz, Jürgen @@oth@@ Weitzel, Jeffrey N. @@oth@@ Williams, Heinric @@oth@@ Winship, Ingrid @@oth@@ Wise, Paul E. @@oth@@ Wods, Julie @@oth@@ Woods, Michael O. @@oth@@ Yamaguchi, Tatsuro @@oth@@ Zachariae, Silke @@oth@@ Zahary, Mohd N. @@oth@@ Hopper, John L. @@oth@@ Haile, Robert W. @@oth@@ Macrae, Finlay A. @@oth@@ Möslein, Gabriela @@oth@@ Jenkins, Mark A. @@oth@@ |
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|
| author |
Win, Aung Ko |
| spellingShingle |
Win, Aung Ko ddc 570 fid BIODIV bkl 35.70 bkl 42.12 Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study |
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Win, Aung Ko |
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Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study |
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Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study |
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variation in the risk of colorectal cancer in families with lynch syndrome: a retrospective cohort study |
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Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study |
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Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. |
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Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. |
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Existing clinical practice guidelines for carriers of pathogenic variants of DNA mismatch repair genes (Lynch syndrome) are based on the mean age-specific cumulative risk (penetrance) of colorectal cancer for all carriers of pathogenic variants in the same gene. We aimed to estimate the variation in the penetrance of colorectal cancer between carriers of pathogenic variants in the same gene by sex and continent of residence. |
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Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study |
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Dowty, James G. Reece, Jeanette C. Lee, Grant Templeton, Allyson S. Plazzer, John-Paul Buchanan, Daniel D. Akagi, Kiwamu Aksoy, Seçil Alonso, Angel Alvarez, Karin Amor, David J. Ankathil, Ravindran Aretz, Stefan Arnold, Julie L. Aronson, Melyssa Austin, Rachel Backman, Ann-Sofie Bajwa-ten Broeke, Sanne W. Barca-Tierno, Verónica Barwell, Julian Bernstein, Inge Berthet, Pascaline Betz, Beate Bignon, Yves-Jean Boisjoli, Talya Bonadona, Valérie Briollais, Laurent Brunet, Joan Bucksch, Karolin Buecher, Bruno Buettner, Reinhard Burn, John Caldés, Trinidad Capella, Gabriel Caron, Olivier Casey, Graham Chew, Min H. Choi, Yun-hee Church, James Clendenning, Mark Colas, Chrystelle Cops, Elisa J. Coupier, Isabelle Cruz-Correa, Marcia de la Chapelle, Albert de Wind, Niels Dębniak, Tadeusz Della Valle, Adriana Delnatte, Capuccine Dhooge, Marion Dominguez-Valentin, Mev Drouet, Youenn Duijkers, Floor A. Engel, Christoph Esperon, Patricia Evans, D. Gareth Falcón de Vargas, Aída Figueiredo, Jane C Foulkes, William Fourme, Emmanuelle Frebourg, Thierry Gallinger, Steven Garre, Pilar Genuardi, Maurizio Gerdes, Anne-Marie Gima, Lauren M. Giraud, Sophie Goodwin, Annabel Görgens, Heike Green, Kate Guillem, Jose Guillén-Ponce, Carmen Guimbaud, Roselyne Guindalini, Rodrigo S.C. Half, Elizabeth E. Hall, Michael J Hampel, Heather Hansen, Thomas V.O. Heinimann, Karl Hes, Frederik J. Hill, James Ho, Judy W.C. Holinski-Feder, Elke Hoogerbrugge, Nicoline Hüneburg, Robert Huntley, Vanessa James, Paul A. Jensen, Uffe B John, Thomas Juhari, Wan K.W. Kalady, Matthew Kastrinos, Fay Kloor, Matthias Kohonen-Corish, Maija RJ Krogh, Lotte N. Kupfer, Sonia S. Ladabaum, Uri Lagerstedt-Robinson, Kristina Lalloo, Fiona Lasset, Christine Latchford, Andrew Laurent-Puig, Pierre Lautrup, Charlotte K. Leggett, Barbara A. Lejeune, Sophie LeMarchand, Loic Ligtenberg, Marjolijn Lindor, Noralane Loeffler, Markus Longy, Michel Lopez, Francisco Lowery, Jan Lubiński, Jan Lucassen, Anneke M Lynch, Patrick M. Malińska, Karolina Matsubara, Nagahide Mecklin, Jukka-Pekka Møller, Pål Monahan, Kevin Morrison, Patrick J. Nattermann, Jacob Navarro, Matilde Neffa, Florencia Neklason, Deborah Newcomb, Polly A. Ngeow, Joanne Nichols, Cassandra Nielsen, Maartje Nixon, Dawn M. Nogues, Catherine Okkels, Henrik Olschwang, Sylviane Pachter, Nicholas Pai, Rish K. Palmero, Edenir I. Pande, Mala Parry, Susan Patel, Swati G. Pearlman, Rachel Perne, Claudia Pineda, Marta Poplawski, Nicola K Pylvänäinen, Kirsi Qiu, Jay Rahner, Nils Ramesar, Raj Rasmussen, Lene J. Redler, Silke Reis, Rui M. Ricciardiello, Luigi Rogoża-Janiszewska, Emilia Rosty, Christophe Samadder, N. Jewel Sampson, Julian R. Schackert, Hans K. Schmiegel, Wolff Schulmann, Karsten Schuster, Helène Scott, Rodney Senter, Leigha Seppälä, Toni T Shtoyerman, Rakefet Sijmons, Rolf H. Snyder, Carrie Solomon, Ilana B. Soto, Jose Luis Southey, Melissa C. Spigelman, Allan Spirandelli, Florencia Spurdle, Amanda B. Steinke-Lange, Verena Stoffel, Elena M. Strassburg, Christian P. Sunde, Lone Susman, Rachel Syngal, Sapna Tanakaya, Kohji Tezcan, Gülçin Therkildsen, Christina Thibodeau, Steve Tomita, Naohiro Tucker, Katherine M. Tunca, Berrin Turchetti, Daniela Uhrhammer, Nancy Utsunomiya, Joji Vaccaro, Carlos van Duijnhoven, Fränzel J.B. van Wanzeele, Meghan J. Vangala, Deepak B. Vasen, Hans F.A. von Knebel Doeberitz, Magnus von Salomé, Jenny Wadt, Karin A.W. Ward, Robyn L. Weitz, Jürgen Weitzel, Jeffrey N. Williams, Heinric Winship, Ingrid Wise, Paul E. Wods, Julie Woods, Michael O. Yamaguchi, Tatsuro Zachariae, Silke Zahary, Mohd N. Hopper, John L. Haile, Robert W. Macrae, Finlay A. Möslein, Gabriela Jenkins, Mark A. |
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