Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access
Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteri...
Ausführliche Beschreibung
Autor*in: |
Khalil, Ibrahim [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021transfer abstract |
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Schlagwörter: |
Enterotoxigenic Escherichia coli (ETEC) |
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Umfang: |
12 |
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Übergeordnetes Werk: |
Enthalten in: Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement - Li, Yaoyao ELSEVIER, 2022, Amsterdam |
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Übergeordnetes Werk: |
volume:39 ; year:2021 ; number:31 ; day:13 ; month:07 ; pages:4266-4277 ; extent:12 |
Links: |
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DOI / URN: |
10.1016/j.vaccine.2021.04.018 |
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520 | |a Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. | ||
650 | 7 | |a Enterotoxigenic Escherichia coli (ETEC) |2 Elsevier | |
650 | 7 | |a Diarrhoeal diseases |2 Elsevier | |
650 | 7 | |a Vaccine research |2 Elsevier | |
650 | 7 | |a Childhood growth and development |2 Elsevier | |
650 | 7 | |a Disease burden |2 Elsevier | |
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10.1016/j.vaccine.2021.04.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001440.pica (DE-627)ELV05453528X (ELSEVIER)S0264-410X(21)00453-9 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Khalil, Ibrahim verfasserin aut Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access 2021transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Enterotoxigenic Escherichia coli (ETEC) Elsevier Diarrhoeal diseases Elsevier Vaccine research Elsevier Childhood growth and development Elsevier Disease burden Elsevier Walker, Richard oth Porter, Chad K. oth Muhib, Farzana oth Chilengi, Roma oth Cravioto, Alejandro oth Guerrant, Richard oth Svennerholm, Ann-Mari oth Qadri, Firdausi oth Baqar, Shahida oth Kosek, Margaret oth Kang, Gagandeep oth Lanata, Claudio oth Armah, George oth Wierzba, Thomas oth Hasso-Agopsowicz, Mateusz oth Giersing, Birgitte oth Louis Bourgeois, A. oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:31 day:13 month:07 pages:4266-4277 extent:12 https://doi.org/10.1016/j.vaccine.2021.04.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 31 13 0713 4266-4277 12 |
spelling |
10.1016/j.vaccine.2021.04.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001440.pica (DE-627)ELV05453528X (ELSEVIER)S0264-410X(21)00453-9 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Khalil, Ibrahim verfasserin aut Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access 2021transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Enterotoxigenic Escherichia coli (ETEC) Elsevier Diarrhoeal diseases Elsevier Vaccine research Elsevier Childhood growth and development Elsevier Disease burden Elsevier Walker, Richard oth Porter, Chad K. oth Muhib, Farzana oth Chilengi, Roma oth Cravioto, Alejandro oth Guerrant, Richard oth Svennerholm, Ann-Mari oth Qadri, Firdausi oth Baqar, Shahida oth Kosek, Margaret oth Kang, Gagandeep oth Lanata, Claudio oth Armah, George oth Wierzba, Thomas oth Hasso-Agopsowicz, Mateusz oth Giersing, Birgitte oth Louis Bourgeois, A. oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:31 day:13 month:07 pages:4266-4277 extent:12 https://doi.org/10.1016/j.vaccine.2021.04.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 31 13 0713 4266-4277 12 |
allfields_unstemmed |
10.1016/j.vaccine.2021.04.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001440.pica (DE-627)ELV05453528X (ELSEVIER)S0264-410X(21)00453-9 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Khalil, Ibrahim verfasserin aut Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access 2021transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Enterotoxigenic Escherichia coli (ETEC) Elsevier Diarrhoeal diseases Elsevier Vaccine research Elsevier Childhood growth and development Elsevier Disease burden Elsevier Walker, Richard oth Porter, Chad K. oth Muhib, Farzana oth Chilengi, Roma oth Cravioto, Alejandro oth Guerrant, Richard oth Svennerholm, Ann-Mari oth Qadri, Firdausi oth Baqar, Shahida oth Kosek, Margaret oth Kang, Gagandeep oth Lanata, Claudio oth Armah, George oth Wierzba, Thomas oth Hasso-Agopsowicz, Mateusz oth Giersing, Birgitte oth Louis Bourgeois, A. oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:31 day:13 month:07 pages:4266-4277 extent:12 https://doi.org/10.1016/j.vaccine.2021.04.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 31 13 0713 4266-4277 12 |
allfieldsGer |
10.1016/j.vaccine.2021.04.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001440.pica (DE-627)ELV05453528X (ELSEVIER)S0264-410X(21)00453-9 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Khalil, Ibrahim verfasserin aut Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access 2021transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Enterotoxigenic Escherichia coli (ETEC) Elsevier Diarrhoeal diseases Elsevier Vaccine research Elsevier Childhood growth and development Elsevier Disease burden Elsevier Walker, Richard oth Porter, Chad K. oth Muhib, Farzana oth Chilengi, Roma oth Cravioto, Alejandro oth Guerrant, Richard oth Svennerholm, Ann-Mari oth Qadri, Firdausi oth Baqar, Shahida oth Kosek, Margaret oth Kang, Gagandeep oth Lanata, Claudio oth Armah, George oth Wierzba, Thomas oth Hasso-Agopsowicz, Mateusz oth Giersing, Birgitte oth Louis Bourgeois, A. oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:31 day:13 month:07 pages:4266-4277 extent:12 https://doi.org/10.1016/j.vaccine.2021.04.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 31 13 0713 4266-4277 12 |
allfieldsSound |
10.1016/j.vaccine.2021.04.018 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001440.pica (DE-627)ELV05453528X (ELSEVIER)S0264-410X(21)00453-9 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Khalil, Ibrahim verfasserin aut Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access 2021transfer abstract 12 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. Enterotoxigenic Escherichia coli (ETEC) Elsevier Diarrhoeal diseases Elsevier Vaccine research Elsevier Childhood growth and development Elsevier Disease burden Elsevier Walker, Richard oth Porter, Chad K. oth Muhib, Farzana oth Chilengi, Roma oth Cravioto, Alejandro oth Guerrant, Richard oth Svennerholm, Ann-Mari oth Qadri, Firdausi oth Baqar, Shahida oth Kosek, Margaret oth Kang, Gagandeep oth Lanata, Claudio oth Armah, George oth Wierzba, Thomas oth Hasso-Agopsowicz, Mateusz oth Giersing, Birgitte oth Louis Bourgeois, A. oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:31 day:13 month:07 pages:4266-4277 extent:12 https://doi.org/10.1016/j.vaccine.2021.04.018 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 31 13 0713 4266-4277 12 |
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Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access |
abstract |
Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. |
abstractGer |
Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. |
abstract_unstemmed |
Diarrhoeal disease attributable to enterotoxigenic Escherichia coli (ETEC) causes substantial morbidity and mortality predominantly in paediatric populations in low- and middle-income countries. In addition to acute illness, there is an increasing appreciation of the long-term consequences of enteric infections, including ETEC, on childhood growth and development. Provision of potable water and sanitation and appropriate clinical care for acute illness are critical to reduce the ETEC burden. However, these interventions are not always practical and may not achieve equitable and sustainable coverage. Vaccination may be the most cost-effective and equitable means of primary prevention; however, additional data are needed to accelerate the investment and guide the decision-making process for ETEC vaccines. |
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Enterotoxigenic Escherichia coli (ETEC) vaccines: Priority activities to enable product development, licensure, and global access |
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