Culturing cells with mast cell phenotype and function: Comparison of peripheral blood and bone marrow as a source.
Studies on the mechanisms that govern mast cell (MC) functions are hindered by the difficulties in isolating sufficient numbers of these tissue-resident cells. Therefore, many research groups use cultured human MCs obtained out of progenitor cells. However, these culture methods significantly differ...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Elst, Jessy [verfasserIn] |
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E-Artikel |
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Englisch |
| Erschienen: |
2021 |
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| Übergeordnetes Werk: |
Enthalten in: 969: Cesarean prevalence rates overtime by maternal characteristics - Thompson, Jennifer A. ELSEVIER, 2018, JIM, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:495 ; year:2021 ; pages:0 |
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| DOI / URN: |
10.1016/j.jim.2021.113061 |
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| 520 | |a Studies on the mechanisms that govern mast cell (MC) functions are hindered by the difficulties in isolating sufficient numbers of these tissue-resident cells. Therefore, many research groups use cultured human MCs obtained out of progenitor cells. However, these culture methods significantly differ regarding primary source material, culture durations and conditions. Consequently, the finally obtained cells are likely to exhibit morphological, phenotypical and/or functional heterogeneity. | ||
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Culturing cells with mast cell phenotype and function: Comparison of peripheral blood and bone marrow as a source. |
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Studies on the mechanisms that govern mast cell (MC) functions are hindered by the difficulties in isolating sufficient numbers of these tissue-resident cells. Therefore, many research groups use cultured human MCs obtained out of progenitor cells. However, these culture methods significantly differ regarding primary source material, culture durations and conditions. Consequently, the finally obtained cells are likely to exhibit morphological, phenotypical and/or functional heterogeneity. |
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Studies on the mechanisms that govern mast cell (MC) functions are hindered by the difficulties in isolating sufficient numbers of these tissue-resident cells. Therefore, many research groups use cultured human MCs obtained out of progenitor cells. However, these culture methods significantly differ regarding primary source material, culture durations and conditions. Consequently, the finally obtained cells are likely to exhibit morphological, phenotypical and/or functional heterogeneity. |
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Studies on the mechanisms that govern mast cell (MC) functions are hindered by the difficulties in isolating sufficient numbers of these tissue-resident cells. Therefore, many research groups use cultured human MCs obtained out of progenitor cells. However, these culture methods significantly differ regarding primary source material, culture durations and conditions. Consequently, the finally obtained cells are likely to exhibit morphological, phenotypical and/or functional heterogeneity. |
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Culturing cells with mast cell phenotype and function: Comparison of peripheral blood and bone marrow as a source. |
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Ebo, Didier G. Faber, Margaretha A. Van Gasse, Athina L. Decuyper, Ine I. van der Poorten, Marie-Line M. Bridts, Chris H. De Puysseleyr, Leander P. Mertens, Christel Hagendorens, Margo M. De Clerck, Luc S. Walschot, Mark Verlinden, Anke Berger, Daniela Valent, Peter Sabato, Vito |
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Ebo, Didier G. Faber, Margaretha A. Van Gasse, Athina L. Decuyper, Ine I. van der Poorten, Marie-Line M. Bridts, Chris H. De Puysseleyr, Leander P. Mertens, Christel Hagendorens, Margo M. De Clerck, Luc S. Walschot, Mark Verlinden, Anke Berger, Daniela Valent, Peter Sabato, Vito |
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10.1016/j.jim.2021.113061 |
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