Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee
The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray di...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Liu, Yaowen [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2021transfer abstract |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
Enthalten in: Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners - Fetters, Lisa ELSEVIER, 2021, EES : official journal of the International Society of Ecotoxicology and Environmental safety, Amsterdam |
|---|---|
| Übergeordnetes Werk: |
volume:224 ; year:2021 ; pages:0 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.ecoenv.2021.112694 |
|---|
| Katalog-ID: |
ELV055117325 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV055117325 | ||
| 003 | DE-627 | ||
| 005 | 20230626041226.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220105s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ecoenv.2021.112694 |2 doi | |
| 028 | 5 | 2 | |a /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica |
| 035 | |a (DE-627)ELV055117325 | ||
| 035 | |a (ELSEVIER)S0147-6513(21)00806-X | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 610 |q VZ |
| 084 | |a 44.63 |2 bkl | ||
| 100 | 1 | |a Liu, Yaowen |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee |
| 264 | 1 | |c 2021transfer abstract | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a nicht spezifiziert |b z |2 rdamedia | ||
| 338 | |a nicht spezifiziert |b zu |2 rdacarrier | ||
| 520 | |a The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. | ||
| 520 | |a The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. | ||
| 650 | 7 | |a Risk assessment |2 Elsevier | |
| 650 | 7 | |a Zebra fish |2 Elsevier | |
| 650 | 7 | |a Instant coffee |2 Elsevier | |
| 650 | 7 | |a Nano-SiO2 |2 Elsevier | |
| 700 | 1 | |a Huang, Ying |4 oth | |
| 700 | 1 | |a Mou, Zhen |4 oth | |
| 700 | 1 | |a Li, Rui |4 oth | |
| 700 | 1 | |a Hossen, Md Alomgir |4 oth | |
| 700 | 1 | |a Dai, Jianwu |4 oth | |
| 700 | 1 | |a Qin, Wen |4 oth | |
| 700 | 1 | |a Lee, KangJu |4 oth | |
| 773 | 0 | 8 | |i Enthalten in |n Elsevier |a Fetters, Lisa ELSEVIER |t Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners |d 2021 |d EES : official journal of the International Society of Ecotoxicology and Environmental safety |g Amsterdam |w (DE-627)ELV006765629 |
| 773 | 1 | 8 | |g volume:224 |g year:2021 |g pages:0 |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.ecoenv.2021.112694 |3 Volltext |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 936 | b | k | |a 44.63 |j Krankenpflege |q VZ |
| 951 | |a AR | ||
| 952 | |d 224 |j 2021 |h 0 | ||
| author_variant |
y l yl |
|---|---|
| matchkey_str |
liuyaowenhuangyingmouzhenliruihossenmdal:2021----:hrceiainnpeiiayaeyvlainfaoi2sl |
| hierarchy_sort_str |
2021transfer abstract |
| bklnumber |
44.63 |
| publishDate |
2021 |
| allfields |
10.1016/j.ecoenv.2021.112694 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica (DE-627)ELV055117325 (ELSEVIER)S0147-6513(21)00806-X DE-627 ger DE-627 rakwb eng 610 VZ 44.63 bkl Liu, Yaowen verfasserin aut Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Elsevier Huang, Ying oth Mou, Zhen oth Li, Rui oth Hossen, Md Alomgir oth Dai, Jianwu oth Qin, Wen oth Lee, KangJu oth Enthalten in Elsevier Fetters, Lisa ELSEVIER Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners 2021 EES : official journal of the International Society of Ecotoxicology and Environmental safety Amsterdam (DE-627)ELV006765629 volume:224 year:2021 pages:0 https://doi.org/10.1016/j.ecoenv.2021.112694 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.63 Krankenpflege VZ AR 224 2021 0 |
| spelling |
10.1016/j.ecoenv.2021.112694 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica (DE-627)ELV055117325 (ELSEVIER)S0147-6513(21)00806-X DE-627 ger DE-627 rakwb eng 610 VZ 44.63 bkl Liu, Yaowen verfasserin aut Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Elsevier Huang, Ying oth Mou, Zhen oth Li, Rui oth Hossen, Md Alomgir oth Dai, Jianwu oth Qin, Wen oth Lee, KangJu oth Enthalten in Elsevier Fetters, Lisa ELSEVIER Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners 2021 EES : official journal of the International Society of Ecotoxicology and Environmental safety Amsterdam (DE-627)ELV006765629 volume:224 year:2021 pages:0 https://doi.org/10.1016/j.ecoenv.2021.112694 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.63 Krankenpflege VZ AR 224 2021 0 |
| allfields_unstemmed |
10.1016/j.ecoenv.2021.112694 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica (DE-627)ELV055117325 (ELSEVIER)S0147-6513(21)00806-X DE-627 ger DE-627 rakwb eng 610 VZ 44.63 bkl Liu, Yaowen verfasserin aut Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Elsevier Huang, Ying oth Mou, Zhen oth Li, Rui oth Hossen, Md Alomgir oth Dai, Jianwu oth Qin, Wen oth Lee, KangJu oth Enthalten in Elsevier Fetters, Lisa ELSEVIER Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners 2021 EES : official journal of the International Society of Ecotoxicology and Environmental safety Amsterdam (DE-627)ELV006765629 volume:224 year:2021 pages:0 https://doi.org/10.1016/j.ecoenv.2021.112694 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.63 Krankenpflege VZ AR 224 2021 0 |
| allfieldsGer |
10.1016/j.ecoenv.2021.112694 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica (DE-627)ELV055117325 (ELSEVIER)S0147-6513(21)00806-X DE-627 ger DE-627 rakwb eng 610 VZ 44.63 bkl Liu, Yaowen verfasserin aut Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Elsevier Huang, Ying oth Mou, Zhen oth Li, Rui oth Hossen, Md Alomgir oth Dai, Jianwu oth Qin, Wen oth Lee, KangJu oth Enthalten in Elsevier Fetters, Lisa ELSEVIER Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners 2021 EES : official journal of the International Society of Ecotoxicology and Environmental safety Amsterdam (DE-627)ELV006765629 volume:224 year:2021 pages:0 https://doi.org/10.1016/j.ecoenv.2021.112694 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.63 Krankenpflege VZ AR 224 2021 0 |
| allfieldsSound |
10.1016/j.ecoenv.2021.112694 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica (DE-627)ELV055117325 (ELSEVIER)S0147-6513(21)00806-X DE-627 ger DE-627 rakwb eng 610 VZ 44.63 bkl Liu, Yaowen verfasserin aut Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Elsevier Huang, Ying oth Mou, Zhen oth Li, Rui oth Hossen, Md Alomgir oth Dai, Jianwu oth Qin, Wen oth Lee, KangJu oth Enthalten in Elsevier Fetters, Lisa ELSEVIER Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners 2021 EES : official journal of the International Society of Ecotoxicology and Environmental safety Amsterdam (DE-627)ELV006765629 volume:224 year:2021 pages:0 https://doi.org/10.1016/j.ecoenv.2021.112694 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U 44.63 Krankenpflege VZ AR 224 2021 0 |
| language |
English |
| source |
Enthalten in Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners Amsterdam volume:224 year:2021 pages:0 |
| sourceStr |
Enthalten in Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners Amsterdam volume:224 year:2021 pages:0 |
| format_phy_str_mv |
Article |
| bklname |
Krankenpflege |
| institution |
findex.gbv.de |
| topic_facet |
Risk assessment Zebra fish Instant coffee Nano-SiO2 |
| dewey-raw |
610 |
| isfreeaccess_bool |
false |
| container_title |
Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners |
| authorswithroles_txt_mv |
Liu, Yaowen @@aut@@ Huang, Ying @@oth@@ Mou, Zhen @@oth@@ Li, Rui @@oth@@ Hossen, Md Alomgir @@oth@@ Dai, Jianwu @@oth@@ Qin, Wen @@oth@@ Lee, KangJu @@oth@@ |
| publishDateDaySort_date |
2021-01-01T00:00:00Z |
| hierarchy_top_id |
ELV006765629 |
| dewey-sort |
3610 |
| id |
ELV055117325 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV055117325</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626041226.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220105s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ecoenv.2021.112694</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV055117325</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0147-6513(21)00806-X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.63</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Liu, Yaowen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021transfer abstract</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Risk assessment</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Zebra fish</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Instant coffee</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Nano-SiO2</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Huang, Ying</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mou, Zhen</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Rui</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hossen, Md Alomgir</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dai, Jianwu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Qin, Wen</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lee, KangJu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Fetters, Lisa ELSEVIER</subfield><subfield code="t">Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners</subfield><subfield code="d">2021</subfield><subfield code="d">EES : official journal of the International Society of Ecotoxicology and Environmental safety</subfield><subfield code="g">Amsterdam</subfield><subfield code="w">(DE-627)ELV006765629</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:224</subfield><subfield code="g">year:2021</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.ecoenv.2021.112694</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.63</subfield><subfield code="j">Krankenpflege</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">224</subfield><subfield code="j">2021</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| author |
Liu, Yaowen |
| spellingShingle |
Liu, Yaowen ddc 610 bkl 44.63 Elsevier Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee |
| authorStr |
Liu, Yaowen |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)ELV006765629 |
| format |
electronic Article |
| dewey-ones |
610 - Medicine & health |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| topic_title |
610 VZ 44.63 bkl Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 Elsevier |
| topic |
ddc 610 bkl 44.63 Elsevier Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 |
| topic_unstemmed |
ddc 610 bkl 44.63 Elsevier Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 |
| topic_browse |
ddc 610 bkl 44.63 Elsevier Risk assessment Elsevier Zebra fish Elsevier Instant coffee Elsevier Nano-SiO2 |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
zu |
| author2_variant |
y h yh z m zm r l rl m a h ma mah j d jd w q wq k l kl |
| hierarchy_parent_title |
Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners |
| hierarchy_parent_id |
ELV006765629 |
| dewey-tens |
610 - Medicine & health |
| hierarchy_top_title |
Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)ELV006765629 |
| title |
Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee |
| ctrlnum |
(DE-627)ELV055117325 (ELSEVIER)S0147-6513(21)00806-X |
| title_full |
Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee |
| author_sort |
Liu, Yaowen |
| journal |
Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners |
| journalStr |
Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
600 - Technology |
| recordtype |
marc |
| publishDateSort |
2021 |
| contenttype_str_mv |
zzz |
| container_start_page |
0 |
| author_browse |
Liu, Yaowen |
| container_volume |
224 |
| class |
610 VZ 44.63 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Liu, Yaowen |
| doi_str_mv |
10.1016/j.ecoenv.2021.112694 |
| dewey-full |
610 |
| title_sort |
characterization and preliminary safety evaluation of nano-sio2 isolated from instant coffee |
| title_auth |
Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee |
| abstract |
The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. |
| abstractGer |
The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. |
| abstract_unstemmed |
The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U |
| title_short |
Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee |
| url |
https://doi.org/10.1016/j.ecoenv.2021.112694 |
| remote_bool |
true |
| author2 |
Huang, Ying Mou, Zhen Li, Rui Hossen, Md Alomgir Dai, Jianwu Qin, Wen Lee, KangJu |
| author2Str |
Huang, Ying Mou, Zhen Li, Rui Hossen, Md Alomgir Dai, Jianwu Qin, Wen Lee, KangJu |
| ppnlink |
ELV006765629 |
| mediatype_str_mv |
z |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| author2_role |
oth oth oth oth oth oth oth |
| doi_str |
10.1016/j.ecoenv.2021.112694 |
| up_date |
2024-07-06T16:39:55.584Z |
| _version_ |
1803848510958731264 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV055117325</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230626041226.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220105s2021 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ecoenv.2021.112694</subfield><subfield code="2">doi</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">/cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001516.pica</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV055117325</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S0147-6513(21)00806-X</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">610</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">44.63</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Liu, Yaowen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Characterization and preliminary safety evaluation of nano-SiO2 isolated from instant coffee</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021transfer abstract</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">z</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zu</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The physiological and toxicological evaluation of nano-silicon dioxide (nano-SiO2) particles in food is important for ensuring food safety. In this study, nano-SiO2 particles isolated from five brands of instant coffee, were structurally characterized using transmission electron microscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, dynamic light scattering, and zeta potential analyses. Their toxicity was assessed by measuring cell viability, membrane integrity, and reactive oxygen species (ROS) levels in model gastrointestinal cells (GES-1 and Caco-2). Additionally, mortality, deformity rate, heart rate and death of whole zebra fish embryos were measured. The five types of nano-SiO2 samples comprised amorphous particles with a purity of approximately 99%, which met the food additive standard. Considering that the original particle size ranged from 10 to 50 nm, the samples were classified as nano-SiO2 food additives. Nano-SiO2 did not significantly impact the activity of GES-1 or Caco-2 cells, and no significant cell membrane damage was observed (Caco-2 cells exhibited mild micro damage); however, a slight increase in intracellular RPS levels was detected. Moreover, nano-SiO2 was found to cause head deformity, pericardial edema, yolk sac edema and tail bending. Collectively, the results show that nano-SiO2 time- and dose-dependently affects GES-1 and Caco-2 cell viability, as well as the mortality, heart rate, and abnormality rate of zebra fish embryos. Specifically, a high concentration (≥ 200 μg/mL) and long exposure time (≥ 48 h) of food additive nano-SiO2 affected GES-1, Caco-2 cells, and the gastrointestinal tract in zebra fish embryos.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Risk assessment</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Zebra fish</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Instant coffee</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Nano-SiO2</subfield><subfield code="2">Elsevier</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Huang, Ying</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mou, Zhen</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Li, Rui</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hossen, Md Alomgir</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dai, Jianwu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Qin, Wen</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Lee, KangJu</subfield><subfield code="4">oth</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="n">Elsevier</subfield><subfield code="a">Fetters, Lisa ELSEVIER</subfield><subfield code="t">Erysipelas, the “Other” Cellulitis: A Practical Guide for Nurse Practitioners</subfield><subfield code="d">2021</subfield><subfield code="d">EES : official journal of the International Society of Ecotoxicology and Environmental safety</subfield><subfield code="g">Amsterdam</subfield><subfield code="w">(DE-627)ELV006765629</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:224</subfield><subfield code="g">year:2021</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.ecoenv.2021.112694</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">44.63</subfield><subfield code="j">Krankenpflege</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">224</subfield><subfield code="j">2021</subfield><subfield code="h">0</subfield></datafield></record></collection>
|
| score |
7.4032135 |