Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate anti...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Park, Wook-Jin [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021transfer abstract |
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| Schlagwörter: |
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| Umfang: |
9 |
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| Übergeordnetes Werk: |
Enthalten in: Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement - Li, Yaoyao ELSEVIER, 2022, Amsterdam |
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| Übergeordnetes Werk: |
volume:39 ; year:2021 ; number:45 ; day:29 ; month:10 ; pages:6644-6652 ; extent:9 |
| Links: |
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| DOI / URN: |
10.1016/j.vaccine.2021.09.067 |
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| 520 | |a Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. | ||
| 520 | |a Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. | ||
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| 650 | 7 | |a Rotavirus |2 Elsevier | |
| 650 | 7 | |a ΔVP8* |2 Elsevier | |
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| 650 | 7 | |a Carrier protein |2 Elsevier | |
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10.1016/j.vaccine.2021.09.067 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001552.pica (DE-627)ELV055587003 (ELSEVIER)S0264-410X(21)01282-2 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Park, Wook-Jin verfasserin aut Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus 2021transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein Elsevier Yoon, Yeon-Kyung oth Kim, Youngmi oth Park, Ji-Sun oth Pansuriya, Ruchirkumar oth Cho, Sang-Nae oth Seok, Yeong-Jae oth Ganapathy, Ravi oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:45 day:29 month:10 pages:6644-6652 extent:9 https://doi.org/10.1016/j.vaccine.2021.09.067 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 45 29 1029 6644-6652 9 |
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10.1016/j.vaccine.2021.09.067 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001552.pica (DE-627)ELV055587003 (ELSEVIER)S0264-410X(21)01282-2 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Park, Wook-Jin verfasserin aut Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus 2021transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein Elsevier Yoon, Yeon-Kyung oth Kim, Youngmi oth Park, Ji-Sun oth Pansuriya, Ruchirkumar oth Cho, Sang-Nae oth Seok, Yeong-Jae oth Ganapathy, Ravi oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:45 day:29 month:10 pages:6644-6652 extent:9 https://doi.org/10.1016/j.vaccine.2021.09.067 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 45 29 1029 6644-6652 9 |
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10.1016/j.vaccine.2021.09.067 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001552.pica (DE-627)ELV055587003 (ELSEVIER)S0264-410X(21)01282-2 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Park, Wook-Jin verfasserin aut Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus 2021transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein Elsevier Yoon, Yeon-Kyung oth Kim, Youngmi oth Park, Ji-Sun oth Pansuriya, Ruchirkumar oth Cho, Sang-Nae oth Seok, Yeong-Jae oth Ganapathy, Ravi oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:45 day:29 month:10 pages:6644-6652 extent:9 https://doi.org/10.1016/j.vaccine.2021.09.067 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 45 29 1029 6644-6652 9 |
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10.1016/j.vaccine.2021.09.067 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001552.pica (DE-627)ELV055587003 (ELSEVIER)S0264-410X(21)01282-2 DE-627 ger DE-627 rakwb eng 630 640 VZ 48.00 bkl Park, Wook-Jin verfasserin aut Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus 2021transfer abstract 9 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein Elsevier Yoon, Yeon-Kyung oth Kim, Youngmi oth Park, Ji-Sun oth Pansuriya, Ruchirkumar oth Cho, Sang-Nae oth Seok, Yeong-Jae oth Ganapathy, Ravi oth Enthalten in Elsevier Li, Yaoyao ELSEVIER Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement 2022 Amsterdam (DE-627)ELV007884451 volume:39 year:2021 number:45 day:29 month:10 pages:6644-6652 extent:9 https://doi.org/10.1016/j.vaccine.2021.09.067 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-FOR 48.00 Land- und Forstwirtschaft: Allgemeines VZ AR 39 2021 45 29 1029 6644-6652 9 |
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Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement |
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Park, Wook-Jin |
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Park, Wook-Jin ddc 630 bkl 48.00 Elsevier Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus |
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630 640 VZ 48.00 bkl Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein Elsevier |
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ddc 630 bkl 48.00 Elsevier Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein |
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ddc 630 bkl 48.00 Elsevier Tuberculosis Elsevier Rotavirus Elsevier ΔVP8* Elsevier Conjugate vaccine Elsevier Carrier protein |
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Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement |
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Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement |
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Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus |
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Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus |
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Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement |
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Quantifying contributions of leaf area and longevity to leaf area duration under increased planting density and nitrogen input regimens during maize yield improvement |
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10.1016/j.vaccine.2021.09.067 |
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development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from mycobacterium tuberculosis conjugated to δvp8* protein from rotavirus |
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Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus |
| abstract |
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. |
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Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. |
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Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide. In addition to its primary role, which is to help generate a T cell-mediate long-lasting immune response directed against the carbohydrate antigen, the carrier protein in a glycoconjugate vaccine can also play an important role as a protective antigen. Among carrier proteins currently used in licensed conjugate vaccines, non-typeable Haemophilus influenzae protein D has been used as an antigenically active carrier protein. Our previous studies also indicate that some carrier proteins provide B cell epitopes, along with T cell helper epitopes. |
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Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus |
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Yoon, Yeon-Kyung Kim, Youngmi Park, Ji-Sun Pansuriya, Ruchirkumar Cho, Sang-Nae Seok, Yeong-Jae Ganapathy, Ravi |
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Yoon, Yeon-Kyung Kim, Youngmi Park, Ji-Sun Pansuriya, Ruchirkumar Cho, Sang-Nae Seok, Yeong-Jae Ganapathy, Ravi |
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