Haematological issues in neonates with neonatal encephalopathy treated with hypothermia
Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dys...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Isweisi, Eman [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021transfer abstract |
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| Übergeordnetes Werk: |
Enthalten in: Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis - Chen, Yuzhong ELSEVIER, 2021, SN, London |
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| Übergeordnetes Werk: |
volume:26 ; year:2021 ; number:4 ; pages:0 |
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| DOI / URN: |
10.1016/j.siny.2021.101270 |
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| 520 | |a Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. | ||
| 520 | |a Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. | ||
| 650 | 7 | |a Thrombophilia |2 Elsevier | |
| 650 | 7 | |a Anaemia |2 Elsevier | |
| 650 | 7 | |a Neonatal encephalopathy |2 Elsevier | |
| 650 | 7 | |a Platelets |2 Elsevier | |
| 650 | 7 | |a Coagulopathy |2 Elsevier | |
| 700 | 1 | |a Moore, Carmel Maria |4 oth | |
| 700 | 1 | |a Hurley, Tim |4 oth | |
| 700 | 1 | |a Sola-Visner, Martha |4 oth | |
| 700 | 1 | |a McCallion, Naomi |4 oth | |
| 700 | 1 | |a Ainle, Fionnuala Ni |4 oth | |
| 700 | 1 | |a Zareen, Zunera |4 oth | |
| 700 | 1 | |a Sweetman, Deirdre U. |4 oth | |
| 700 | 1 | |a Curley, Anna E. |4 oth | |
| 700 | 1 | |a Molloy, Eleanor J. |4 oth | |
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10.1016/j.siny.2021.101270 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001578.pica (DE-627)ELV055833993 (ELSEVIER)S1744-165X(21)00078-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Isweisi, Eman verfasserin aut Haematological issues in neonates with neonatal encephalopathy treated with hypothermia 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Thrombophilia Elsevier Anaemia Elsevier Neonatal encephalopathy Elsevier Platelets Elsevier Coagulopathy Elsevier Moore, Carmel Maria oth Hurley, Tim oth Sola-Visner, Martha oth McCallion, Naomi oth Ainle, Fionnuala Ni oth Zareen, Zunera oth Sweetman, Deirdre U. oth Curley, Anna E. oth Molloy, Eleanor J. oth Enthalten in Saunders Chen, Yuzhong ELSEVIER Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis 2021 SN London (DE-627)ELV006285945 volume:26 year:2021 number:4 pages:0 https://doi.org/10.1016/j.siny.2021.101270 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.00 Medizin: Allgemeines VZ AR 26 2021 4 0 |
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10.1016/j.siny.2021.101270 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001578.pica (DE-627)ELV055833993 (ELSEVIER)S1744-165X(21)00078-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Isweisi, Eman verfasserin aut Haematological issues in neonates with neonatal encephalopathy treated with hypothermia 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Thrombophilia Elsevier Anaemia Elsevier Neonatal encephalopathy Elsevier Platelets Elsevier Coagulopathy Elsevier Moore, Carmel Maria oth Hurley, Tim oth Sola-Visner, Martha oth McCallion, Naomi oth Ainle, Fionnuala Ni oth Zareen, Zunera oth Sweetman, Deirdre U. oth Curley, Anna E. oth Molloy, Eleanor J. oth Enthalten in Saunders Chen, Yuzhong ELSEVIER Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis 2021 SN London (DE-627)ELV006285945 volume:26 year:2021 number:4 pages:0 https://doi.org/10.1016/j.siny.2021.101270 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.00 Medizin: Allgemeines VZ AR 26 2021 4 0 |
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10.1016/j.siny.2021.101270 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001578.pica (DE-627)ELV055833993 (ELSEVIER)S1744-165X(21)00078-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Isweisi, Eman verfasserin aut Haematological issues in neonates with neonatal encephalopathy treated with hypothermia 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Thrombophilia Elsevier Anaemia Elsevier Neonatal encephalopathy Elsevier Platelets Elsevier Coagulopathy Elsevier Moore, Carmel Maria oth Hurley, Tim oth Sola-Visner, Martha oth McCallion, Naomi oth Ainle, Fionnuala Ni oth Zareen, Zunera oth Sweetman, Deirdre U. oth Curley, Anna E. oth Molloy, Eleanor J. oth Enthalten in Saunders Chen, Yuzhong ELSEVIER Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis 2021 SN London (DE-627)ELV006285945 volume:26 year:2021 number:4 pages:0 https://doi.org/10.1016/j.siny.2021.101270 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.00 Medizin: Allgemeines VZ AR 26 2021 4 0 |
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10.1016/j.siny.2021.101270 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001578.pica (DE-627)ELV055833993 (ELSEVIER)S1744-165X(21)00078-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Isweisi, Eman verfasserin aut Haematological issues in neonates with neonatal encephalopathy treated with hypothermia 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Thrombophilia Elsevier Anaemia Elsevier Neonatal encephalopathy Elsevier Platelets Elsevier Coagulopathy Elsevier Moore, Carmel Maria oth Hurley, Tim oth Sola-Visner, Martha oth McCallion, Naomi oth Ainle, Fionnuala Ni oth Zareen, Zunera oth Sweetman, Deirdre U. oth Curley, Anna E. oth Molloy, Eleanor J. oth Enthalten in Saunders Chen, Yuzhong ELSEVIER Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis 2021 SN London (DE-627)ELV006285945 volume:26 year:2021 number:4 pages:0 https://doi.org/10.1016/j.siny.2021.101270 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.00 Medizin: Allgemeines VZ AR 26 2021 4 0 |
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10.1016/j.siny.2021.101270 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001578.pica (DE-627)ELV055833993 (ELSEVIER)S1744-165X(21)00078-0 DE-627 ger DE-627 rakwb eng 610 VZ 44.00 bkl Isweisi, Eman verfasserin aut Haematological issues in neonates with neonatal encephalopathy treated with hypothermia 2021transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. Thrombophilia Elsevier Anaemia Elsevier Neonatal encephalopathy Elsevier Platelets Elsevier Coagulopathy Elsevier Moore, Carmel Maria oth Hurley, Tim oth Sola-Visner, Martha oth McCallion, Naomi oth Ainle, Fionnuala Ni oth Zareen, Zunera oth Sweetman, Deirdre U. oth Curley, Anna E. oth Molloy, Eleanor J. oth Enthalten in Saunders Chen, Yuzhong ELSEVIER Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis 2021 SN London (DE-627)ELV006285945 volume:26 year:2021 number:4 pages:0 https://doi.org/10.1016/j.siny.2021.101270 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.00 Medizin: Allgemeines VZ AR 26 2021 4 0 |
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English |
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Enthalten in Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis London volume:26 year:2021 number:4 pages:0 |
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Enthalten in Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis London volume:26 year:2021 number:4 pages:0 |
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Efficacy and safety of first-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) combined with chemotherapy or antiangiogenic therapy as first-line treatment in patients with EGFR-mutant non-small cell lung cancer: A systematic review and meta-analysis |
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Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. |
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Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. |
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Neonatal encephalopathy (NE) is associated with abnormality of neurological function and involves multiorgan dysfunction. There are long-term complications such as cerebral palsy and developmental delay. Cardiac, renal, neurological and other organ dysfunctions are well described. Haematological dysfunction is relatively common and includes anaemia, thrombocytopenia, monocyte and neutrophil activation, hypofibrinogenemia and coagulopathy. There is a lack of consensus definitions of hematological parameters and optimal levels for intervention due to the lack of interventional studies in term neonates and the lack of knowledge of the optimal values during therapeutic hypothermia. However, derangements in hematological values are also associated with neurodevelopmental outcomes. This article outlines the different hematological complications associated with NE and therapeutic hypothermia and suggests a framework for management. |
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