Chronic pain and neuroinflammation
• Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth fac...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Vergne-Salle, Pascale [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2021 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
Enthalten in: Calendar of Events - 2014, revue du rhumatisme, international edition : official publication of the French Society of Rheumatology, Paris |
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| Übergeordnetes Werk: |
volume:88 ; year:2021 ; number:6 ; pages:0 |
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| DOI / URN: |
10.1016/j.jbspin.2021.105222 |
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| 520 | |a • Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. | ||
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10.1016/j.jbspin.2021.105222 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001641.pica (DE-627)ELV055893295 (ELSEVIER)S1297-319X(21)00095-6 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Vergne-Salle, Pascale verfasserin aut Chronic pain and neuroinflammation 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. Astrocytes Elsevier Central sensitization Elsevier Neuroinflammation Elsevier Chronic pain Elsevier Immune system Elsevier Microglia Elsevier Bertin, Philippe oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:88 year:2021 number:6 pages:0 https://doi.org/10.1016/j.jbspin.2021.105222 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 88 2021 6 0 |
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10.1016/j.jbspin.2021.105222 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001641.pica (DE-627)ELV055893295 (ELSEVIER)S1297-319X(21)00095-6 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Vergne-Salle, Pascale verfasserin aut Chronic pain and neuroinflammation 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. Astrocytes Elsevier Central sensitization Elsevier Neuroinflammation Elsevier Chronic pain Elsevier Immune system Elsevier Microglia Elsevier Bertin, Philippe oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:88 year:2021 number:6 pages:0 https://doi.org/10.1016/j.jbspin.2021.105222 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 88 2021 6 0 |
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10.1016/j.jbspin.2021.105222 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001641.pica (DE-627)ELV055893295 (ELSEVIER)S1297-319X(21)00095-6 DE-627 ger DE-627 rakwb eng 610 VZ 540 VZ 35.10 bkl Vergne-Salle, Pascale verfasserin aut Chronic pain and neuroinflammation 2021 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. Astrocytes Elsevier Central sensitization Elsevier Neuroinflammation Elsevier Chronic pain Elsevier Immune system Elsevier Microglia Elsevier Bertin, Philippe oth Enthalten in Elsevier Calendar of Events 2014 revue du rhumatisme, international edition : official publication of the French Society of Rheumatology Paris (DE-627)ELV017983630 volume:88 year:2021 number:6 pages:0 https://doi.org/10.1016/j.jbspin.2021.105222 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 35.10 Physikalische Chemie: Allgemeines VZ AR 88 2021 6 0 |
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• Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. |
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• Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. |
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• Central sensitization is based on a two-way interaction between the nervous system and immune system represented by the microglia. • Activation of the microglia or microgliosis and activation of astrocytes lead to hypersensitivity and neuronal plasticity in the central nervous system. • Growth factors (BDNF), cytokines (IL-1, TNF, IL-6) and chemokines play a major part in this neuroinflammation. • Microgliosis can extend to certain supraspinal structures involved in pain modulation and the emotional and cognitive aspects of pain. |
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