iPSC-derived cortical neurons to study sporadic Alzheimer disease: A transcriptome comparison with post-mortem brain samples

• The transcriptome of iPSC-derived cortical neurons and brain biopsies were assessed. • sAD iPSC-derived neurons & brain samples showed many similar AD-related processes. • iPSCs exposed to toxicants increases our knowledge of their AD-inducing properties.

Gespeichert in:
Autor*in:

Verheijen, M.C.T [verfasserIn]

Krauskopf, J.

Caiment, F.

Nazaruk, M.

Wen, Q.F.

van Herwijnen, M.H.M.

Hauser, D.A.

Gajjar, M.

Verfaillie, C.

Vermeiren, Y.

De Deyn, P.P.

Wittens, M.M.J.

Sieben, A.

Engelborghs, S.

Dejonckheere, W.

Princen, K.

Griffioen, G.

Roggen, E.L.

Briedé, J.J.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2022

Schlagwörter:

iPSCs

Toxicology

sAD

Alzheimerogens

Alzheimers disease

Gene expression

Umfang:

11

Übergeordnetes Werk:

Enthalten in: Toxicology letters - Chen, Yun-Ru ELSEVIER, 2019, an international journal for the rapid publication of short reports on all aspects of toxicology especially mechanisms of toxicity, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:356 ; year:2022 ; day:1 ; month:03 ; pages:89-99 ; extent:11

Links:

Volltext

DOI / URN:

10.1016/j.toxlet.2021.12.009

Katalog-ID:

ELV056629559

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