Baseline PD-L1 expression and tumour-infiltrated lymphocyte status predict the efficacy of durvalumab consolidation therapy after chemoradiotherapy in unresectable locally advanced patients with non-small-cell lung cancer

Chemoradiotherapy (CRT) followed by durvalumab treatment improved prognosis in unresectable locally advanced non-small-cell lung cancer (LA-NSCLC). This study aimed to evaluate whether the status of the immune-related tumour microenvironment (TME) at baseline associates with the efficacy.

Gespeichert in:
Autor*in:

Shirasawa, Masayuki [verfasserIn]

Yoshida, Tatsuya

Imabayashi, Tatsuya

Okuma, Kae

Matsumoto, Yuji

Masuda, Ken

Shinno, Yuki

Okuma, Yusuke

Goto, Yasushi

Horinouchi, Hidehito

Tsuchida, Takaaki

Yamamoto, Noboru

Nakayama, Yuko

Watanabe, Shun-ichi

Motoi, Noriko

Ohe, Yuichiro

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2022

Schlagwörter:

and PD-L1 expression

Durvalumab

Tumour-infiltrated lymphocytes

CD8

Locally advanced non-small-cell carcinoma

Umfang:

10

Übergeordnetes Werk:

Enthalten in: The effect of early cognitive therapy in improving cognitive functions using neuropsychology and diffusion tensor imaging measurements following mild traumatic brain injury: A pilot study - Hamzah, N. ELSEVIER, 2018, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:162 ; year:2022 ; pages:1-10 ; extent:10

Links:

Volltext

DOI / URN:

10.1016/j.ejca.2021.11.013

Katalog-ID:

ELV056678592

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