Asperflomide and asperflosamide, new N-methylated cyclopeptides from the marine sponge-derived fungus Aspergillus flocculosus 16D-1
Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Mar...
Ausführliche Beschreibung
Gespeichert in:
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Jiao, Fu-Rong [verfasserIn] |
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E-Artikel |
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Englisch |
| Erschienen: |
2022 |
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Enthalten in: Therapeutic Advances in Pediatric Multiple Sclerosis - 2013, the international journal for the rapid publication of full original research papers and critical reviews in organic chemistry, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:109 ; year:2022 ; day:12 ; month:03 ; pages:0 |
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10.1016/j.tet.2021.132579 |
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| 520 | |a Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Marfey's analysis. These cyclopeptides showed weak tankyrase1/2 inhibitory activity at the centration of 40 μM. | ||
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10.1016/j.tet.2021.132579 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001692.pica (DE-627)ELV056975775 (ELSEVIER)S0040-4020(21)00883-8 DE-627 ger DE-627 rakwb eng 610 VZ 150 VZ LING DE-30 fid 77.00 bkl Jiao, Fu-Rong verfasserin aut Asperflomide and asperflosamide, new N-methylated cyclopeptides from the marine sponge-derived fungus Aspergillus flocculosus 16D-1 2022 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Marfey's analysis. These cyclopeptides showed weak tankyrase1/2 inhibitory activity at the centration of 40 μM. Cyclopeptide Elsevier Tankyrase1/ 2 Elsevier Asperflosamide Elsevier Aspergillus flocculosus 16D-1 Elsevier Asperflomide Elsevier Zhu, Hong-Rui oth Gu, Bin-Bin oth Wu, Yin oth Sun, Fan oth Wang, Shu-Ping oth Zhang, Ao oth Jiao, Wei-Hua oth Xu, Shi-Hai oth Lin, Hou-Wen oth Enthalten in Elsevier Science Therapeutic Advances in Pediatric Multiple Sclerosis 2013 the international journal for the rapid publication of full original research papers and critical reviews in organic chemistry Amsterdam [u.a.] (DE-627)ELV011938943 volume:109 year:2022 day:12 month:03 pages:0 https://doi.org/10.1016/j.tet.2021.132579 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING 77.00 Psychologie: Allgemeines VZ AR 109 2022 12 0312 0 |
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10.1016/j.tet.2021.132579 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001692.pica (DE-627)ELV056975775 (ELSEVIER)S0040-4020(21)00883-8 DE-627 ger DE-627 rakwb eng 610 VZ 150 VZ LING DE-30 fid 77.00 bkl Jiao, Fu-Rong verfasserin aut Asperflomide and asperflosamide, new N-methylated cyclopeptides from the marine sponge-derived fungus Aspergillus flocculosus 16D-1 2022 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Marfey's analysis. These cyclopeptides showed weak tankyrase1/2 inhibitory activity at the centration of 40 μM. Cyclopeptide Elsevier Tankyrase1/ 2 Elsevier Asperflosamide Elsevier Aspergillus flocculosus 16D-1 Elsevier Asperflomide Elsevier Zhu, Hong-Rui oth Gu, Bin-Bin oth Wu, Yin oth Sun, Fan oth Wang, Shu-Ping oth Zhang, Ao oth Jiao, Wei-Hua oth Xu, Shi-Hai oth Lin, Hou-Wen oth Enthalten in Elsevier Science Therapeutic Advances in Pediatric Multiple Sclerosis 2013 the international journal for the rapid publication of full original research papers and critical reviews in organic chemistry Amsterdam [u.a.] (DE-627)ELV011938943 volume:109 year:2022 day:12 month:03 pages:0 https://doi.org/10.1016/j.tet.2021.132579 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U FID-LING 77.00 Psychologie: Allgemeines VZ AR 109 2022 12 0312 0 |
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asperflomide and asperflosamide, new n-methylated cyclopeptides from the marine sponge-derived fungus aspergillus flocculosus 16d-1 |
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Asperflomide and asperflosamide, new N-methylated cyclopeptides from the marine sponge-derived fungus Aspergillus flocculosus 16D-1 |
| abstract |
Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Marfey's analysis. These cyclopeptides showed weak tankyrase1/2 inhibitory activity at the centration of 40 μM. |
| abstractGer |
Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Marfey's analysis. These cyclopeptides showed weak tankyrase1/2 inhibitory activity at the centration of 40 μM. |
| abstract_unstemmed |
Two new N-methylated cyclopeptides, asperflomide (1) and asperflosamide (2), were obtained from the marine sponge-derived fungus Aspergillus flocculosus 16D-1. The planer structure were determined by NMR spectroscopic data and the absolute configurations of the amino acids were elucidated by the Marfey's analysis. These cyclopeptides showed weak tankyrase1/2 inhibitory activity at the centration of 40 μM. |
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Asperflomide and asperflosamide, new N-methylated cyclopeptides from the marine sponge-derived fungus Aspergillus flocculosus 16D-1 |
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https://doi.org/10.1016/j.tet.2021.132579 |
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Zhu, Hong-Rui Gu, Bin-Bin Wu, Yin Sun, Fan Wang, Shu-Ping Zhang, Ao Jiao, Wei-Hua Xu, Shi-Hai Lin, Hou-Wen |
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Zhu, Hong-Rui Gu, Bin-Bin Wu, Yin Sun, Fan Wang, Shu-Ping Zhang, Ao Jiao, Wei-Hua Xu, Shi-Hai Lin, Hou-Wen |
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