Self-aggregation of the proteolytic forms of Verteporfin: An in silico and in vitro study
• Self-aggregation of the proteolytic forms of Verteporfin was described. • In water/ethanol mix, self-aggregation follows: neutral > monoanionic > dicationic. • J-type aggregates are formed in high water content medium and inside cells. • Water mostly governs the self-aggregation of Verteporf...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Calori, Italo Rodrigo [verfasserIn] |
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E-Artikel |
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Englisch |
| Erschienen: |
2022 |
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| Übergeordnetes Werk: |
Enthalten in: Application of a fuzzy-logic based model for risk assessment in additive manufacturing R&D projects - Moreno-Cabezali, Belen Maria ELSEVIER, 2020, an international journal devoted to fundamental aspects of structure, interactions and dynamic processes in simple, molecular and complex liquids, New York, NY [u.a.] |
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| Übergeordnetes Werk: |
volume:352 ; year:2022 ; day:15 ; month:04 ; pages:0 |
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| DOI / URN: |
10.1016/j.molliq.2022.118640 |
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| 520 | |a • Self-aggregation of the proteolytic forms of Verteporfin was described. • In water/ethanol mix, self-aggregation follows: neutral > monoanionic > dicationic. • J-type aggregates are formed in high water content medium and inside cells. • Water mostly governs the self-aggregation of Verteporfin inside cells. • No preferential self-aggregation in acid lysosomes of U87MG cells line occurs. | ||
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self-aggregation of the proteolytic forms of verteporfin: an in silico and in vitro study |
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Self-aggregation of the proteolytic forms of Verteporfin: An in silico and in vitro study |
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• Self-aggregation of the proteolytic forms of Verteporfin was described. • In water/ethanol mix, self-aggregation follows: neutral > monoanionic > dicationic. • J-type aggregates are formed in high water content medium and inside cells. • Water mostly governs the self-aggregation of Verteporfin inside cells. • No preferential self-aggregation in acid lysosomes of U87MG cells line occurs. |
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• Self-aggregation of the proteolytic forms of Verteporfin was described. • In water/ethanol mix, self-aggregation follows: neutral > monoanionic > dicationic. • J-type aggregates are formed in high water content medium and inside cells. • Water mostly governs the self-aggregation of Verteporfin inside cells. • No preferential self-aggregation in acid lysosomes of U87MG cells line occurs. |
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• Self-aggregation of the proteolytic forms of Verteporfin was described. • In water/ethanol mix, self-aggregation follows: neutral > monoanionic > dicationic. • J-type aggregates are formed in high water content medium and inside cells. • Water mostly governs the self-aggregation of Verteporfin inside cells. • No preferential self-aggregation in acid lysosomes of U87MG cells line occurs. |
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Self-aggregation of the proteolytic forms of Verteporfin: An in silico and in vitro study |
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Braga, Gustavo Tessaro, André Luiz Caetano, Wilker Tedesco, Antonio Claudio Hioka, Noboru |
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