An improved graph Laplacian regularization method for identifying biomarkers of Alzheimer's disease

• The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable.

Gespeichert in:
Autor*in:

Liu, Liyue [verfasserIn]

Liu, Xiangyu

Zhou, Juan

Wu, Weihua

Li, Xiong

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2022

Schlagwörter:

Pathway enrichment analysis

Protein-protein interaction network

Diseases prediction model

Regression model

Systems biology

Übergeordnetes Werk:

Enthalten in: Dissolution versus cementation and its role in determining tight sandstone quality: A case study from the Upper Paleozoic in northeastern Ordos Basin, China - Li, Yong ELSEVIER, 2020, Amsterdam

Übergeordnetes Werk:

volume:543 ; year:2022 ; day:21 ; month:06 ; pages:0

Links:

Volltext

DOI / URN:

10.1016/j.jtbi.2022.111121

Katalog-ID:

ELV057513813

Nicht das Richtige dabei?

Schreiben Sie uns!