An improved graph Laplacian regularization method for identifying biomarkers of Alzheimer's disease
• The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable.
Autor*in: |
Liu, Liyue [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2022 |
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Schlagwörter: |
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Übergeordnetes Werk: |
Enthalten in: Dissolution versus cementation and its role in determining tight sandstone quality: A case study from the Upper Paleozoic in northeastern Ordos Basin, China - Li, Yong ELSEVIER, 2020, Amsterdam |
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Übergeordnetes Werk: |
volume:543 ; year:2022 ; day:21 ; month:06 ; pages:0 |
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DOI / URN: |
10.1016/j.jtbi.2022.111121 |
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10.1016/j.jtbi.2022.111121 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001767.pica (DE-627)ELV057513813 (ELSEVIER)S0022-5193(22)00119-9 DE-627 ger DE-627 rakwb eng 660 VZ Liu, Liyue verfasserin aut An improved graph Laplacian regularization method for identifying biomarkers of Alzheimer's disease 2022 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable. Pathway enrichment analysis Elsevier Protein-protein interaction network Elsevier Diseases prediction model Elsevier Regression model Elsevier Systems biology Elsevier Liu, Xiangyu oth Zhou, Juan oth Wu, Weihua oth Li, Xiong oth Enthalten in Elsevier Ltd Li, Yong ELSEVIER Dissolution versus cementation and its role in determining tight sandstone quality: A case study from the Upper Paleozoic in northeastern Ordos Basin, China 2020 Amsterdam (DE-627)ELV004081676 volume:543 year:2022 day:21 month:06 pages:0 https://doi.org/10.1016/j.jtbi.2022.111121 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA AR 543 2022 21 0621 0 |
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10.1016/j.jtbi.2022.111121 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001767.pica (DE-627)ELV057513813 (ELSEVIER)S0022-5193(22)00119-9 DE-627 ger DE-627 rakwb eng 660 VZ Liu, Liyue verfasserin aut An improved graph Laplacian regularization method for identifying biomarkers of Alzheimer's disease 2022 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier • The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable. Pathway enrichment analysis Elsevier Protein-protein interaction network Elsevier Diseases prediction model Elsevier Regression model Elsevier Systems biology Elsevier Liu, Xiangyu oth Zhou, Juan oth Wu, Weihua oth Li, Xiong oth Enthalten in Elsevier Ltd Li, Yong ELSEVIER Dissolution versus cementation and its role in determining tight sandstone quality: A case study from the Upper Paleozoic in northeastern Ordos Basin, China 2020 Amsterdam (DE-627)ELV004081676 volume:543 year:2022 day:21 month:06 pages:0 https://doi.org/10.1016/j.jtbi.2022.111121 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA AR 543 2022 21 0621 0 |
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an improved graph laplacian regularization method for identifying biomarkers of alzheimer's disease |
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An improved graph Laplacian regularization method for identifying biomarkers of Alzheimer's disease |
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• The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable. |
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• The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable. |
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• The topological information of protein–protein interaction network is combined. • The algorithm is suitable for data with few samples and high gene dimension. • Our method converges quickly and the identified network-based biomarkers are more biologically interpretable. |
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An improved graph Laplacian regularization method for identifying biomarkers of Alzheimer's disease |
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code="a">Li, Yong ELSEVIER</subfield><subfield code="t">Dissolution versus cementation and its role in determining tight sandstone quality: A case study from the Upper Paleozoic in northeastern Ordos Basin, China</subfield><subfield code="d">2020</subfield><subfield code="g">Amsterdam</subfield><subfield code="w">(DE-627)ELV004081676</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:543</subfield><subfield code="g">year:2022</subfield><subfield code="g">day:21</subfield><subfield code="g">month:06</subfield><subfield code="g">pages:0</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.jtbi.2022.111121</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield 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