Immunotherapy response-associated Akkermansia: canary in a coal mine?
Gut microbes can shape cancer immunotherapy responses; however, specific taxa have not been tested prospectively as biomarkers. Derosa and colleagues now demonstrate that the presence of Akkermansia muciniphila in baseline stool samples can be associated with improved outcomes and enhanced antitumor...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Cascone, Tina [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2022 |
|---|
| Umfang: |
3 |
|---|
| Übergeordnetes Werk: |
Enthalten in: The journey of a mental health professional with co-morbid mental health and alcohol use disorder from despair, to acceptance, to advocacy - Thomas, Brandon ELSEVIER, 2023, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:43 ; year:2022 ; number:5 ; pages:337-339 ; extent:3 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.it.2022.03.007 |
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| 520 | |a Gut microbes can shape cancer immunotherapy responses; however, specific taxa have not been tested prospectively as biomarkers. Derosa and colleagues now demonstrate that the presence of Akkermansia muciniphila in baseline stool samples can be associated with improved outcomes and enhanced antitumor immune cell infiltrates in patients with lung cancer treated with immune checkpoint blockade (ICB). | ||
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10.1016/j.it.2022.03.007 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001752.pica (DE-627)ELV057541426 (ELSEVIER)S1471-4906(22)00070-9 DE-627 ger DE-627 rakwb eng Cascone, Tina verfasserin aut Immunotherapy response-associated Akkermansia: canary in a coal mine? 2022 3 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Gut microbes can shape cancer immunotherapy responses; however, specific taxa have not been tested prospectively as biomarkers. Derosa and colleagues now demonstrate that the presence of Akkermansia muciniphila in baseline stool samples can be associated with improved outcomes and enhanced antitumor immune cell infiltrates in patients with lung cancer treated with immune checkpoint blockade (ICB). Chelvanambi, Manoj oth Wargo, Jennifer A. oth Enthalten in Elsevier Science Thomas, Brandon ELSEVIER The journey of a mental health professional with co-morbid mental health and alcohol use disorder from despair, to acceptance, to advocacy 2023 Amsterdam [u.a.] (DE-627)ELV009586830 volume:43 year:2022 number:5 pages:337-339 extent:3 https://doi.org/10.1016/j.it.2022.03.007 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U AR 43 2022 5 337-339 3 |
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Immunotherapy response-associated Akkermansia: canary in a coal mine? |
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Gut microbes can shape cancer immunotherapy responses; however, specific taxa have not been tested prospectively as biomarkers. Derosa and colleagues now demonstrate that the presence of Akkermansia muciniphila in baseline stool samples can be associated with improved outcomes and enhanced antitumor immune cell infiltrates in patients with lung cancer treated with immune checkpoint blockade (ICB). |
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Gut microbes can shape cancer immunotherapy responses; however, specific taxa have not been tested prospectively as biomarkers. Derosa and colleagues now demonstrate that the presence of Akkermansia muciniphila in baseline stool samples can be associated with improved outcomes and enhanced antitumor immune cell infiltrates in patients with lung cancer treated with immune checkpoint blockade (ICB). |
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Gut microbes can shape cancer immunotherapy responses; however, specific taxa have not been tested prospectively as biomarkers. Derosa and colleagues now demonstrate that the presence of Akkermansia muciniphila in baseline stool samples can be associated with improved outcomes and enhanced antitumor immune cell infiltrates in patients with lung cancer treated with immune checkpoint blockade (ICB). |
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