The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)

Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Zhang, Ruiqiang [verfasserIn] Shi, Xueyan Liu, Jinsong Jiang, Ying Wu, Yanping Xu, Yinglei Yang, Caimei

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022transfer abstract

Schlagwörter:	Microflora Toll/NF-κB pathway Antioxidant Bamboo leaf flavonoid Non-specific immunity

Übergeordnetes Werk:	Enthalten in: Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema - Arthur, Jason ELSEVIER, 2022, an international scientific journal covering research on animal nutrition, feeding and technology, Amsterdam [u.a.]
Übergeordnetes Werk:	volume:288 ; year:2022 ; pages:0

Links:	Volltext

DOI / URN:	10.1016/j.anifeedsci.2022.115297

Katalog-ID:	ELV057680108

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245	1	4	\|a The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)
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520			\|a Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs.
520			\|a Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs.
650		7	\|a Microflora \|2 Elsevier
650		7	\|a Toll/NF-κB pathway \|2 Elsevier
650		7	\|a Antioxidant \|2 Elsevier
650		7	\|a Bamboo leaf flavonoid \|2 Elsevier
650		7	\|a Non-specific immunity \|2 Elsevier
700	1		\|a Shi, Xueyan \|4 oth
700	1		\|a Liu, Jinsong \|4 oth
700	1		\|a Jiang, Ying \|4 oth
700	1		\|a Wu, Yanping \|4 oth
700	1		\|a Xu, Yinglei \|4 oth
700	1		\|a Yang, Caimei \|4 oth
773	0	8	\|i Enthalten in \|n Elsevier Science \|a Arthur, Jason ELSEVIER \|t Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema \|d 2022 \|d an international scientific journal covering research on animal nutrition, feeding and technology \|g Amsterdam [u.a.] \|w (DE-627)ELV008918023
773	1	8	\|g volume:288 \|g year:2022 \|g pages:0
856	4	0	\|u https://doi.org/10.1016/j.anifeedsci.2022.115297 \|3 Volltext
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matchkey_str	zhangruiqiangshixueyanliujinsongjiangyin:2022----:hefcsfaboeflvnisnrwhefracimntatoiatttsnitsiamcolroc
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allfields	10.1016/j.anifeedsci.2022.115297 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001770.pica (DE-627)ELV057680108 (ELSEVIER)S0377-8401(22)00095-5 DE-627 ger DE-627 rakwb eng 610 VZ 44.80 bkl Zhang, Ruiqiang verfasserin aut The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis) 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Microflora Elsevier Toll/NF-κB pathway Elsevier Antioxidant Elsevier Bamboo leaf flavonoid Elsevier Non-specific immunity Elsevier Shi, Xueyan oth Liu, Jinsong oth Jiang, Ying oth Wu, Yanping oth Xu, Yinglei oth Yang, Caimei oth Enthalten in Elsevier Science Arthur, Jason ELSEVIER Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema 2022 an international scientific journal covering research on animal nutrition, feeding and technology Amsterdam [u.a.] (DE-627)ELV008918023 volume:288 year:2022 pages:0 https://doi.org/10.1016/j.anifeedsci.2022.115297 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.80 Unfallmedizin Notfallmedizin VZ AR 288 2022 0
spelling	10.1016/j.anifeedsci.2022.115297 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001770.pica (DE-627)ELV057680108 (ELSEVIER)S0377-8401(22)00095-5 DE-627 ger DE-627 rakwb eng 610 VZ 44.80 bkl Zhang, Ruiqiang verfasserin aut The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis) 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Microflora Elsevier Toll/NF-κB pathway Elsevier Antioxidant Elsevier Bamboo leaf flavonoid Elsevier Non-specific immunity Elsevier Shi, Xueyan oth Liu, Jinsong oth Jiang, Ying oth Wu, Yanping oth Xu, Yinglei oth Yang, Caimei oth Enthalten in Elsevier Science Arthur, Jason ELSEVIER Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema 2022 an international scientific journal covering research on animal nutrition, feeding and technology Amsterdam [u.a.] (DE-627)ELV008918023 volume:288 year:2022 pages:0 https://doi.org/10.1016/j.anifeedsci.2022.115297 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.80 Unfallmedizin Notfallmedizin VZ AR 288 2022 0
allfields_unstemmed	10.1016/j.anifeedsci.2022.115297 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001770.pica (DE-627)ELV057680108 (ELSEVIER)S0377-8401(22)00095-5 DE-627 ger DE-627 rakwb eng 610 VZ 44.80 bkl Zhang, Ruiqiang verfasserin aut The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis) 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Microflora Elsevier Toll/NF-κB pathway Elsevier Antioxidant Elsevier Bamboo leaf flavonoid Elsevier Non-specific immunity Elsevier Shi, Xueyan oth Liu, Jinsong oth Jiang, Ying oth Wu, Yanping oth Xu, Yinglei oth Yang, Caimei oth Enthalten in Elsevier Science Arthur, Jason ELSEVIER Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema 2022 an international scientific journal covering research on animal nutrition, feeding and technology Amsterdam [u.a.] (DE-627)ELV008918023 volume:288 year:2022 pages:0 https://doi.org/10.1016/j.anifeedsci.2022.115297 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.80 Unfallmedizin Notfallmedizin VZ AR 288 2022 0
allfieldsGer	10.1016/j.anifeedsci.2022.115297 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001770.pica (DE-627)ELV057680108 (ELSEVIER)S0377-8401(22)00095-5 DE-627 ger DE-627 rakwb eng 610 VZ 44.80 bkl Zhang, Ruiqiang verfasserin aut The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis) 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Microflora Elsevier Toll/NF-κB pathway Elsevier Antioxidant Elsevier Bamboo leaf flavonoid Elsevier Non-specific immunity Elsevier Shi, Xueyan oth Liu, Jinsong oth Jiang, Ying oth Wu, Yanping oth Xu, Yinglei oth Yang, Caimei oth Enthalten in Elsevier Science Arthur, Jason ELSEVIER Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema 2022 an international scientific journal covering research on animal nutrition, feeding and technology Amsterdam [u.a.] (DE-627)ELV008918023 volume:288 year:2022 pages:0 https://doi.org/10.1016/j.anifeedsci.2022.115297 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.80 Unfallmedizin Notfallmedizin VZ AR 288 2022 0
allfieldsSound	10.1016/j.anifeedsci.2022.115297 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001770.pica (DE-627)ELV057680108 (ELSEVIER)S0377-8401(22)00095-5 DE-627 ger DE-627 rakwb eng 610 VZ 44.80 bkl Zhang, Ruiqiang verfasserin aut The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis) 2022transfer abstract nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs. Microflora Elsevier Toll/NF-κB pathway Elsevier Antioxidant Elsevier Bamboo leaf flavonoid Elsevier Non-specific immunity Elsevier Shi, Xueyan oth Liu, Jinsong oth Jiang, Ying oth Wu, Yanping oth Xu, Yinglei oth Yang, Caimei oth Enthalten in Elsevier Science Arthur, Jason ELSEVIER Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema 2022 an international scientific journal covering research on animal nutrition, feeding and technology Amsterdam [u.a.] (DE-627)ELV008918023 volume:288 year:2022 pages:0 https://doi.org/10.1016/j.anifeedsci.2022.115297 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA 44.80 Unfallmedizin Notfallmedizin VZ AR 288 2022 0
language	English
source	Enthalten in Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema Amsterdam [u.a.] volume:288 year:2022 pages:0
sourceStr	Enthalten in Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema Amsterdam [u.a.] volume:288 year:2022 pages:0
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container_title	Clinical predictors of endotracheal intubation in patients presenting to the emergency department with angioedema
authorswithroles_txt_mv	Zhang, Ruiqiang @@aut@@ Shi, Xueyan @@oth@@ Liu, Jinsong @@oth@@ Jiang, Ying @@oth@@ Wu, Yanping @@oth@@ Xu, Yinglei @@oth@@ Yang, Caimei @@oth@@
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title	The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)
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title_full	The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)
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title_sort	effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of chinese mitten crabs (eriocheir sinensis)
title_auth	The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)
abstract	Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs.
abstractGer	Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs.
abstract_unstemmed	Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs.
collection_details	GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OLC-PHA
title_short	The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)
url	https://doi.org/10.1016/j.anifeedsci.2022.115297
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author2	Shi, Xueyan Liu, Jinsong Jiang, Ying Wu, Yanping Xu, Yinglei Yang, Caimei
author2Str	Shi, Xueyan Liu, Jinsong Jiang, Ying Wu, Yanping Xu, Yinglei Yang, Caimei
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doi_str	10.1016/j.anifeedsci.2022.115297
up_date	2024-07-06T16:51:05.535Z
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This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). In conclusion, dietary BLF inclusion improved the growth performance and intestinal microflora, enhanced the non-specific immunity and antioxidant function, activated the Toll/NF-κB pathway in Chinese mitten crabs.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Bamboo leaf flavonoids (BLF) are the mainly bioactive constituents of bamboo leaves and have caused considerable attention for antibacterial, anti-inflammatory, antioxidant, antitumor, and anti-aging activities. This research evaluated dietary (commercial pellet feed form) addition of Phyllostachys BLF effects on growth, non-specific immunity, antioxidant function, and intestinal microflora of Chinese mitten crabs. A total of 216 crabs were randomly sorted into 18 tanks with 6 replicates for each group and 12 crabs per replicate. Crabs were fed with a basal diet supplemented with 0 (control), 500, and 1000 mg/kg BLF, respectively. Results shown that crabs fed diet supplemented with 1000 mg/kg BLF improved the growth performance, enhanced serum phenoloxidase (PO), lysozyme, total antioxidant capacity (T-AOC), and glutathione peroxidase (GPx) levels, increased hepatopancreas T-AOC and total superoxide dismutase (T-SOD) levels, upregulated hepatopancreas Tube and Dif mRNA expression levels compared with the crabs in the control (P < 0.05). The inclusion of 500 mg/kg BLF only increased the serum lysozyme content (P < 0.05). Dietary 500 or 1000 mg/kg BLF addition increased serum T-SOD and catalase activities, enhanced hepatopancreas GPx activity, reduced the serum malondialdehyde content, upregulated the mRNA expression levels of hepatopancreas GPx, toll-like receptors 1, myeloid differentiation factor 88, lysozyme, and prophenoloxidase of crabs (P < 0.05). Crabs in 1000 mg/kg BLF addition group had higher PO activity than that crabs in the 500 mg/kg BLF addition group (P < 0.05). The separated principal co-ordinates analysis revealed that the three groups had different microbiota composition. Both 500 and 1000 mg/kg BLF addition decreased the shannon and chao1 indexes, reduced the abundance of phyla Bacteroidota, enhanced the abundance of phyla Firmicutes and genus Candidatus_Bacilloplasma in intestine microbiota of Chinese mitten crabs (P < 0.05). 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The effects of bamboo leaf flavonoids on growth performance, immunity, antioxidant status, and intestinal microflora of Chinese mitten crabs (Eriocheir sinensis)

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