Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical
Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw mate...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Angelini, Paola [verfasserIn] Flores, Giancarlo Angeles [verfasserIn] Piccirilli, Alessandro [verfasserIn] Venanzoni, Roberto [verfasserIn] Acquaviva, Alessandra [verfasserIn] Di Simone, Simonetta Cristina [verfasserIn] Libero, Maria Loreta [verfasserIn] Tirillini, Bruno [verfasserIn] Zengin, Gokhan [verfasserIn] Chiavaroli, Annalisa [verfasserIn] Recinella, Lucia [verfasserIn] Leone, Sheila [verfasserIn] Brunetti, Luigi [verfasserIn] Orlando, Giustino [verfasserIn] Menghini, Luigi [verfasserIn] Ferrante, Claudio [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2022 |
|---|
| Schlagwörter: |
|---|
| Übergeordnetes Werk: |
Enthalten in: Process biochemistry - Amsterdam [u.a.] : Elsevier Science, 1991, 118 |
|---|---|
| Übergeordnetes Werk: |
volume:118 |
| DOI / URN: |
10.1016/j.procbio.2022.04.019 |
|---|
| Katalog-ID: |
ELV057790736 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | ELV057790736 | ||
| 003 | DE-627 | ||
| 005 | 20240104093422.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220808s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.procbio.2022.04.019 |2 doi | |
| 035 | |a (DE-627)ELV057790736 | ||
| 035 | |a (ELSEVIER)S1359-5113(22)00135-0 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 530 |q VZ |
| 084 | |a 42.30 |2 bkl | ||
| 084 | |a 58.30 |2 bkl | ||
| 084 | |a 58.34 |2 bkl | ||
| 100 | 1 | |a Angelini, Paola |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical |
| 264 | 1 | |c 2022 | |
| 336 | |a nicht spezifiziert |b zzz |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. | ||
| 650 | 4 | |a Vitis vinifera | |
| 650 | 4 | |a Grape byproducts | |
| 650 | 4 | |a Phenolic compounds | |
| 650 | 4 | |a Antiradical effect | |
| 650 | 4 | |a Antimycotic effect | |
| 700 | 1 | |a Flores, Giancarlo Angeles |e verfasserin |4 aut | |
| 700 | 1 | |a Piccirilli, Alessandro |e verfasserin |4 aut | |
| 700 | 1 | |a Venanzoni, Roberto |e verfasserin |4 aut | |
| 700 | 1 | |a Acquaviva, Alessandra |e verfasserin |4 aut | |
| 700 | 1 | |a Di Simone, Simonetta Cristina |e verfasserin |4 aut | |
| 700 | 1 | |a Libero, Maria Loreta |e verfasserin |4 aut | |
| 700 | 1 | |a Tirillini, Bruno |e verfasserin |4 aut | |
| 700 | 1 | |a Zengin, Gokhan |e verfasserin |4 aut | |
| 700 | 1 | |a Chiavaroli, Annalisa |e verfasserin |4 aut | |
| 700 | 1 | |a Recinella, Lucia |e verfasserin |4 aut | |
| 700 | 1 | |a Leone, Sheila |e verfasserin |4 aut | |
| 700 | 1 | |a Brunetti, Luigi |e verfasserin |4 aut | |
| 700 | 1 | |a Orlando, Giustino |e verfasserin |4 aut | |
| 700 | 1 | |a Menghini, Luigi |e verfasserin |4 aut | |
| 700 | 1 | |a Ferrante, Claudio |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Process biochemistry |d Amsterdam [u.a.] : Elsevier Science, 1991 |g 118 |h Online-Ressource |w (DE-627)320570916 |w (DE-600)2016483-X |w (DE-576)259484989 |x 0032-9592 |7 nnns |
| 773 | 1 | 8 | |g volume:118 |
| 912 | |a GBV_USEFLAG_U | ||
| 912 | |a GBV_ELV | ||
| 912 | |a SYSFLAG_U | ||
| 912 | |a GBV_ILN_20 | ||
| 912 | |a GBV_ILN_22 | ||
| 912 | |a GBV_ILN_23 | ||
| 912 | |a GBV_ILN_24 | ||
| 912 | |a GBV_ILN_31 | ||
| 912 | |a GBV_ILN_32 | ||
| 912 | |a GBV_ILN_40 | ||
| 912 | |a GBV_ILN_60 | ||
| 912 | |a GBV_ILN_62 | ||
| 912 | |a GBV_ILN_63 | ||
| 912 | |a GBV_ILN_65 | ||
| 912 | |a GBV_ILN_69 | ||
| 912 | |a GBV_ILN_70 | ||
| 912 | |a GBV_ILN_73 | ||
| 912 | |a GBV_ILN_74 | ||
| 912 | |a GBV_ILN_90 | ||
| 912 | |a GBV_ILN_95 | ||
| 912 | |a GBV_ILN_100 | ||
| 912 | |a GBV_ILN_101 | ||
| 912 | |a GBV_ILN_105 | ||
| 912 | |a GBV_ILN_110 | ||
| 912 | |a GBV_ILN_150 | ||
| 912 | |a GBV_ILN_151 | ||
| 912 | |a GBV_ILN_224 | ||
| 912 | |a GBV_ILN_370 | ||
| 912 | |a GBV_ILN_602 | ||
| 912 | |a GBV_ILN_702 | ||
| 912 | |a GBV_ILN_2003 | ||
| 912 | |a GBV_ILN_2004 | ||
| 912 | |a GBV_ILN_2005 | ||
| 912 | |a GBV_ILN_2011 | ||
| 912 | |a GBV_ILN_2014 | ||
| 912 | |a GBV_ILN_2015 | ||
| 912 | |a GBV_ILN_2020 | ||
| 912 | |a GBV_ILN_2021 | ||
| 912 | |a GBV_ILN_2025 | ||
| 912 | |a GBV_ILN_2027 | ||
| 912 | |a GBV_ILN_2034 | ||
| 912 | |a GBV_ILN_2038 | ||
| 912 | |a GBV_ILN_2044 | ||
| 912 | |a GBV_ILN_2048 | ||
| 912 | |a GBV_ILN_2049 | ||
| 912 | |a GBV_ILN_2050 | ||
| 912 | |a GBV_ILN_2056 | ||
| 912 | |a GBV_ILN_2059 | ||
| 912 | |a GBV_ILN_2061 | ||
| 912 | |a GBV_ILN_2064 | ||
| 912 | |a GBV_ILN_2065 | ||
| 912 | |a GBV_ILN_2068 | ||
| 912 | |a GBV_ILN_2111 | ||
| 912 | |a GBV_ILN_2112 | ||
| 912 | |a GBV_ILN_2113 | ||
| 912 | |a GBV_ILN_2118 | ||
| 912 | |a GBV_ILN_2122 | ||
| 912 | |a GBV_ILN_2129 | ||
| 912 | |a GBV_ILN_2143 | ||
| 912 | |a GBV_ILN_2147 | ||
| 912 | |a GBV_ILN_2148 | ||
| 912 | |a GBV_ILN_2152 | ||
| 912 | |a GBV_ILN_2153 | ||
| 912 | |a GBV_ILN_2190 | ||
| 912 | |a GBV_ILN_2336 | ||
| 912 | |a GBV_ILN_2507 | ||
| 912 | |a GBV_ILN_2522 | ||
| 912 | |a GBV_ILN_4035 | ||
| 912 | |a GBV_ILN_4037 | ||
| 912 | |a GBV_ILN_4112 | ||
| 912 | |a GBV_ILN_4125 | ||
| 912 | |a GBV_ILN_4126 | ||
| 912 | |a GBV_ILN_4242 | ||
| 912 | |a GBV_ILN_4251 | ||
| 912 | |a GBV_ILN_4305 | ||
| 912 | |a GBV_ILN_4313 | ||
| 912 | |a GBV_ILN_4323 | ||
| 912 | |a GBV_ILN_4324 | ||
| 912 | |a GBV_ILN_4326 | ||
| 912 | |a GBV_ILN_4333 | ||
| 912 | |a GBV_ILN_4334 | ||
| 912 | |a GBV_ILN_4335 | ||
| 912 | |a GBV_ILN_4338 | ||
| 912 | |a GBV_ILN_4393 | ||
| 936 | b | k | |a 42.30 |j Mikrobiologie |q VZ |
| 936 | b | k | |a 58.30 |j Biotechnologie |q VZ |
| 936 | b | k | |a 58.34 |j Lebensmitteltechnologie |q VZ |
| 951 | |a AR | ||
| 952 | |d 118 | ||
| author_variant |
p a pa g a f ga gaf a p ap r v rv a a aa s s c d ssc sscd m l l ml mll b t bt g z gz a c ac l r lr s l sl l b lb g o go l m lm c f cf |
|---|---|
| matchkey_str |
article:00329592:2022----::oyhnlcopstoadniirbaatvtoetatotiefogaercsigyrdcsew |
| hierarchy_sort_str |
2022 |
| bklnumber |
42.30 58.30 58.34 |
| publishDate |
2022 |
| allfields |
10.1016/j.procbio.2022.04.019 doi (DE-627)ELV057790736 (ELSEVIER)S1359-5113(22)00135-0 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Angelini, Paola verfasserin aut Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect Flores, Giancarlo Angeles verfasserin aut Piccirilli, Alessandro verfasserin aut Venanzoni, Roberto verfasserin aut Acquaviva, Alessandra verfasserin aut Di Simone, Simonetta Cristina verfasserin aut Libero, Maria Loreta verfasserin aut Tirillini, Bruno verfasserin aut Zengin, Gokhan verfasserin aut Chiavaroli, Annalisa verfasserin aut Recinella, Lucia verfasserin aut Leone, Sheila verfasserin aut Brunetti, Luigi verfasserin aut Orlando, Giustino verfasserin aut Menghini, Luigi verfasserin aut Ferrante, Claudio verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 118 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:118 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 118 |
| spelling |
10.1016/j.procbio.2022.04.019 doi (DE-627)ELV057790736 (ELSEVIER)S1359-5113(22)00135-0 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Angelini, Paola verfasserin aut Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect Flores, Giancarlo Angeles verfasserin aut Piccirilli, Alessandro verfasserin aut Venanzoni, Roberto verfasserin aut Acquaviva, Alessandra verfasserin aut Di Simone, Simonetta Cristina verfasserin aut Libero, Maria Loreta verfasserin aut Tirillini, Bruno verfasserin aut Zengin, Gokhan verfasserin aut Chiavaroli, Annalisa verfasserin aut Recinella, Lucia verfasserin aut Leone, Sheila verfasserin aut Brunetti, Luigi verfasserin aut Orlando, Giustino verfasserin aut Menghini, Luigi verfasserin aut Ferrante, Claudio verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 118 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:118 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 118 |
| allfields_unstemmed |
10.1016/j.procbio.2022.04.019 doi (DE-627)ELV057790736 (ELSEVIER)S1359-5113(22)00135-0 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Angelini, Paola verfasserin aut Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect Flores, Giancarlo Angeles verfasserin aut Piccirilli, Alessandro verfasserin aut Venanzoni, Roberto verfasserin aut Acquaviva, Alessandra verfasserin aut Di Simone, Simonetta Cristina verfasserin aut Libero, Maria Loreta verfasserin aut Tirillini, Bruno verfasserin aut Zengin, Gokhan verfasserin aut Chiavaroli, Annalisa verfasserin aut Recinella, Lucia verfasserin aut Leone, Sheila verfasserin aut Brunetti, Luigi verfasserin aut Orlando, Giustino verfasserin aut Menghini, Luigi verfasserin aut Ferrante, Claudio verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 118 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:118 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 118 |
| allfieldsGer |
10.1016/j.procbio.2022.04.019 doi (DE-627)ELV057790736 (ELSEVIER)S1359-5113(22)00135-0 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Angelini, Paola verfasserin aut Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect Flores, Giancarlo Angeles verfasserin aut Piccirilli, Alessandro verfasserin aut Venanzoni, Roberto verfasserin aut Acquaviva, Alessandra verfasserin aut Di Simone, Simonetta Cristina verfasserin aut Libero, Maria Loreta verfasserin aut Tirillini, Bruno verfasserin aut Zengin, Gokhan verfasserin aut Chiavaroli, Annalisa verfasserin aut Recinella, Lucia verfasserin aut Leone, Sheila verfasserin aut Brunetti, Luigi verfasserin aut Orlando, Giustino verfasserin aut Menghini, Luigi verfasserin aut Ferrante, Claudio verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 118 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:118 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 118 |
| allfieldsSound |
10.1016/j.procbio.2022.04.019 doi (DE-627)ELV057790736 (ELSEVIER)S1359-5113(22)00135-0 DE-627 ger DE-627 rda eng 530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Angelini, Paola verfasserin aut Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical 2022 nicht spezifiziert zzz rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect Flores, Giancarlo Angeles verfasserin aut Piccirilli, Alessandro verfasserin aut Venanzoni, Roberto verfasserin aut Acquaviva, Alessandra verfasserin aut Di Simone, Simonetta Cristina verfasserin aut Libero, Maria Loreta verfasserin aut Tirillini, Bruno verfasserin aut Zengin, Gokhan verfasserin aut Chiavaroli, Annalisa verfasserin aut Recinella, Lucia verfasserin aut Leone, Sheila verfasserin aut Brunetti, Luigi verfasserin aut Orlando, Giustino verfasserin aut Menghini, Luigi verfasserin aut Ferrante, Claudio verfasserin aut Enthalten in Process biochemistry Amsterdam [u.a.] : Elsevier Science, 1991 118 Online-Ressource (DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 0032-9592 nnns volume:118 GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 42.30 Mikrobiologie VZ 58.30 Biotechnologie VZ 58.34 Lebensmitteltechnologie VZ AR 118 |
| language |
English |
| source |
Enthalten in Process biochemistry 118 volume:118 |
| sourceStr |
Enthalten in Process biochemistry 118 volume:118 |
| format_phy_str_mv |
Article |
| bklname |
Mikrobiologie Biotechnologie Lebensmitteltechnologie |
| institution |
findex.gbv.de |
| topic_facet |
Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect |
| dewey-raw |
530 |
| isfreeaccess_bool |
false |
| container_title |
Process biochemistry |
| authorswithroles_txt_mv |
Angelini, Paola @@aut@@ Flores, Giancarlo Angeles @@aut@@ Piccirilli, Alessandro @@aut@@ Venanzoni, Roberto @@aut@@ Acquaviva, Alessandra @@aut@@ Di Simone, Simonetta Cristina @@aut@@ Libero, Maria Loreta @@aut@@ Tirillini, Bruno @@aut@@ Zengin, Gokhan @@aut@@ Chiavaroli, Annalisa @@aut@@ Recinella, Lucia @@aut@@ Leone, Sheila @@aut@@ Brunetti, Luigi @@aut@@ Orlando, Giustino @@aut@@ Menghini, Luigi @@aut@@ Ferrante, Claudio @@aut@@ |
| publishDateDaySort_date |
2022-01-01T00:00:00Z |
| hierarchy_top_id |
320570916 |
| dewey-sort |
3530 |
| id |
ELV057790736 |
| language_de |
englisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV057790736</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240104093422.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220808s2022 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.procbio.2022.04.019</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV057790736</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1359-5113(22)00135-0</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">42.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.34</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Angelini, Paola</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Vitis vinifera</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Grape byproducts</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Phenolic compounds</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antiradical effect</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antimycotic effect</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Flores, Giancarlo Angeles</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Piccirilli, Alessandro</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Venanzoni, Roberto</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Acquaviva, Alessandra</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Di Simone, Simonetta Cristina</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Libero, Maria Loreta</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tirillini, Bruno</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zengin, Gokhan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chiavaroli, Annalisa</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Recinella, Lucia</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Leone, Sheila</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brunetti, Luigi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Orlando, Giustino</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Menghini, Luigi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ferrante, Claudio</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Process biochemistry</subfield><subfield code="d">Amsterdam [u.a.] : Elsevier Science, 1991</subfield><subfield code="g">118</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)320570916</subfield><subfield code="w">(DE-600)2016483-X</subfield><subfield code="w">(DE-576)259484989</subfield><subfield code="x">0032-9592</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_101</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_150</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">42.30</subfield><subfield code="j">Mikrobiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.30</subfield><subfield code="j">Biotechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.34</subfield><subfield code="j">Lebensmitteltechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">118</subfield></datafield></record></collection>
|
| author |
Angelini, Paola |
| spellingShingle |
Angelini, Paola ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Vitis vinifera misc Grape byproducts misc Phenolic compounds misc Antiradical effect misc Antimycotic effect Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical |
| authorStr |
Angelini, Paola |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)320570916 |
| format |
electronic Article |
| dewey-ones |
530 - Physics |
| delete_txt_mv |
keep |
| author_role |
aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut aut |
| collection |
elsevier |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
0032-9592 |
| topic_title |
530 VZ 42.30 bkl 58.30 bkl 58.34 bkl Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical Vitis vinifera Grape byproducts Phenolic compounds Antiradical effect Antimycotic effect |
| topic |
ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Vitis vinifera misc Grape byproducts misc Phenolic compounds misc Antiradical effect misc Antimycotic effect |
| topic_unstemmed |
ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Vitis vinifera misc Grape byproducts misc Phenolic compounds misc Antiradical effect misc Antimycotic effect |
| topic_browse |
ddc 530 bkl 42.30 bkl 58.30 bkl 58.34 misc Vitis vinifera misc Grape byproducts misc Phenolic compounds misc Antiradical effect misc Antimycotic effect |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Process biochemistry |
| hierarchy_parent_id |
320570916 |
| dewey-tens |
530 - Physics |
| hierarchy_top_title |
Process biochemistry |
| isfreeaccess_txt |
false |
| familylinks_str_mv |
(DE-627)320570916 (DE-600)2016483-X (DE-576)259484989 |
| title |
Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical |
| ctrlnum |
(DE-627)ELV057790736 (ELSEVIER)S1359-5113(22)00135-0 |
| title_full |
Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical |
| author_sort |
Angelini, Paola |
| journal |
Process biochemistry |
| journalStr |
Process biochemistry |
| lang_code |
eng |
| isOA_bool |
false |
| dewey-hundreds |
500 - Science |
| recordtype |
marc |
| publishDateSort |
2022 |
| contenttype_str_mv |
zzz |
| author_browse |
Angelini, Paola Flores, Giancarlo Angeles Piccirilli, Alessandro Venanzoni, Roberto Acquaviva, Alessandra Di Simone, Simonetta Cristina Libero, Maria Loreta Tirillini, Bruno Zengin, Gokhan Chiavaroli, Annalisa Recinella, Lucia Leone, Sheila Brunetti, Luigi Orlando, Giustino Menghini, Luigi Ferrante, Claudio |
| container_volume |
118 |
| class |
530 VZ 42.30 bkl 58.30 bkl 58.34 bkl |
| format_se |
Elektronische Aufsätze |
| author-letter |
Angelini, Paola |
| doi_str_mv |
10.1016/j.procbio.2022.04.019 |
| dewey-full |
530 |
| author2-role |
verfasserin |
| title_sort |
polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: between green biotechnology and nutraceutical |
| title_auth |
Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical |
| abstract |
Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. |
| abstractGer |
Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. |
| abstract_unstemmed |
Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield. |
| collection_details |
GBV_USEFLAG_U GBV_ELV SYSFLAG_U GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_224 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2336 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 |
| title_short |
Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical |
| remote_bool |
true |
| author2 |
Flores, Giancarlo Angeles Piccirilli, Alessandro Venanzoni, Roberto Acquaviva, Alessandra Di Simone, Simonetta Cristina Libero, Maria Loreta Tirillini, Bruno Zengin, Gokhan Chiavaroli, Annalisa Recinella, Lucia Leone, Sheila Brunetti, Luigi Orlando, Giustino Menghini, Luigi Ferrante, Claudio |
| author2Str |
Flores, Giancarlo Angeles Piccirilli, Alessandro Venanzoni, Roberto Acquaviva, Alessandra Di Simone, Simonetta Cristina Libero, Maria Loreta Tirillini, Bruno Zengin, Gokhan Chiavaroli, Annalisa Recinella, Lucia Leone, Sheila Brunetti, Luigi Orlando, Giustino Menghini, Luigi Ferrante, Claudio |
| ppnlink |
320570916 |
| mediatype_str_mv |
c |
| isOA_txt |
false |
| hochschulschrift_bool |
false |
| doi_str |
10.1016/j.procbio.2022.04.019 |
| up_date |
2024-07-06T17:10:18.621Z |
| _version_ |
1803850422548430848 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">ELV057790736</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20240104093422.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">220808s2022 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.procbio.2022.04.019</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)ELV057790736</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ELSEVIER)S1359-5113(22)00135-0</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">530</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">42.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.30</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">58.34</subfield><subfield code="2">bkl</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Angelini, Paola</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">nicht spezifiziert</subfield><subfield code="b">zzz</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activities of hydroalcoholic extracts obtained from grape pomace and juice of the cultivars Sagrantino, Tintilia, Vernaccia and Falanghina. While the Falanghina hydroalcoholic extract showed the highest total phenol level and antiradical potential, in Sagrantino pomace and Vernaccia juice, the catechin concentration was up to 20-fold higher compared to the other extracts. They also displayed the highest antimycotic effects, especially against Trichophyton rubrum and Arthroderma crocatum. However, their mycostatic effects could be only partially related to the catechin content. Indeed, the putative binding of catechin towards lanosterol-14-α-demethylase, deeply involved in fungal metabolism, would occur at a concentration ten-fold higher compared to the catechin level corresponding to the extracts’ MIC; thus suggesting multiple antimycotic mechanisms. Overall, the present study suggests the valorization of grape by-products that could open new applicative scenarios in the local productive chain, often characterized by high quality wine with low productive yield.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Vitis vinifera</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Grape byproducts</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Phenolic compounds</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antiradical effect</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Antimycotic effect</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Flores, Giancarlo Angeles</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Piccirilli, Alessandro</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Venanzoni, Roberto</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Acquaviva, Alessandra</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Di Simone, Simonetta Cristina</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Libero, Maria Loreta</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tirillini, Bruno</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Zengin, Gokhan</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chiavaroli, Annalisa</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Recinella, Lucia</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Leone, Sheila</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brunetti, Luigi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Orlando, Giustino</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Menghini, Luigi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Ferrante, Claudio</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">Enthalten in</subfield><subfield code="t">Process biochemistry</subfield><subfield code="d">Amsterdam [u.a.] : Elsevier Science, 1991</subfield><subfield code="g">118</subfield><subfield code="h">Online-Ressource</subfield><subfield code="w">(DE-627)320570916</subfield><subfield code="w">(DE-600)2016483-X</subfield><subfield code="w">(DE-576)259484989</subfield><subfield code="x">0032-9592</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ELV</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_U</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_101</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_150</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2336</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">42.30</subfield><subfield code="j">Mikrobiologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.30</subfield><subfield code="j">Biotechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="936" ind1="b" ind2="k"><subfield code="a">58.34</subfield><subfield code="j">Lebensmitteltechnologie</subfield><subfield code="q">VZ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">118</subfield></datafield></record></collection>
|
| score |
7.3993273 |