A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain
Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric m...
Ausführliche Beschreibung
Autor*in: |
Ranger, A. [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2022transfer abstract |
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Umfang: |
8 |
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Übergeordnetes Werk: |
Enthalten in: Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory - Meyer, Theresa ELSEVIER, 2022, a journal of the Royal College of Radiologists, [S.l.] |
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Übergeordnetes Werk: |
volume:34 ; year:2022 ; number:8 ; pages:526-533 ; extent:8 |
Links: |
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DOI / URN: |
10.1016/j.clon.2022.03.020 |
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Katalog-ID: |
ELV058296247 |
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520 | |a Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. | ||
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10.1016/j.clon.2022.03.020 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001825.pica (DE-627)ELV058296247 (ELSEVIER)S0936-6555(22)00175-3 DE-627 ger DE-627 rakwb eng 550 VZ 38.73 bkl 74.41 bkl Ranger, A. verfasserin aut A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain 2022transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. VMAT Elsevier Breast radiotherapy Elsevier toxicity breast radiotherapy Elsevier heart-sparing radiotherapy Elsevier Dunlop, A. oth Hansen, V.N. oth Princewill, G. oth Landeg, S. oth Donovan, E.M. oth Harris, E.J. oth McNair, H.A. oth Haviland, J. oth Kirby, A.M. oth Enthalten in Saunders Meyer, Theresa ELSEVIER Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory 2022 a journal of the Royal College of Radiologists [S.l.] (DE-627)ELV009071989 volume:34 year:2022 number:8 pages:526-533 extent:8 https://doi.org/10.1016/j.clon.2022.03.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO SSG-OPC-GEO 38.73 Geodäsie VZ 74.41 Luftaufnahmen Photogrammetrie VZ AR 34 2022 8 526-533 8 |
spelling |
10.1016/j.clon.2022.03.020 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001825.pica (DE-627)ELV058296247 (ELSEVIER)S0936-6555(22)00175-3 DE-627 ger DE-627 rakwb eng 550 VZ 38.73 bkl 74.41 bkl Ranger, A. verfasserin aut A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain 2022transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. VMAT Elsevier Breast radiotherapy Elsevier toxicity breast radiotherapy Elsevier heart-sparing radiotherapy Elsevier Dunlop, A. oth Hansen, V.N. oth Princewill, G. oth Landeg, S. oth Donovan, E.M. oth Harris, E.J. oth McNair, H.A. oth Haviland, J. oth Kirby, A.M. oth Enthalten in Saunders Meyer, Theresa ELSEVIER Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory 2022 a journal of the Royal College of Radiologists [S.l.] (DE-627)ELV009071989 volume:34 year:2022 number:8 pages:526-533 extent:8 https://doi.org/10.1016/j.clon.2022.03.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO SSG-OPC-GEO 38.73 Geodäsie VZ 74.41 Luftaufnahmen Photogrammetrie VZ AR 34 2022 8 526-533 8 |
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10.1016/j.clon.2022.03.020 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001825.pica (DE-627)ELV058296247 (ELSEVIER)S0936-6555(22)00175-3 DE-627 ger DE-627 rakwb eng 550 VZ 38.73 bkl 74.41 bkl Ranger, A. verfasserin aut A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain 2022transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. VMAT Elsevier Breast radiotherapy Elsevier toxicity breast radiotherapy Elsevier heart-sparing radiotherapy Elsevier Dunlop, A. oth Hansen, V.N. oth Princewill, G. oth Landeg, S. oth Donovan, E.M. oth Harris, E.J. oth McNair, H.A. oth Haviland, J. oth Kirby, A.M. oth Enthalten in Saunders Meyer, Theresa ELSEVIER Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory 2022 a journal of the Royal College of Radiologists [S.l.] (DE-627)ELV009071989 volume:34 year:2022 number:8 pages:526-533 extent:8 https://doi.org/10.1016/j.clon.2022.03.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO SSG-OPC-GEO 38.73 Geodäsie VZ 74.41 Luftaufnahmen Photogrammetrie VZ AR 34 2022 8 526-533 8 |
allfieldsGer |
10.1016/j.clon.2022.03.020 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001825.pica (DE-627)ELV058296247 (ELSEVIER)S0936-6555(22)00175-3 DE-627 ger DE-627 rakwb eng 550 VZ 38.73 bkl 74.41 bkl Ranger, A. verfasserin aut A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain 2022transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. VMAT Elsevier Breast radiotherapy Elsevier toxicity breast radiotherapy Elsevier heart-sparing radiotherapy Elsevier Dunlop, A. oth Hansen, V.N. oth Princewill, G. oth Landeg, S. oth Donovan, E.M. oth Harris, E.J. oth McNair, H.A. oth Haviland, J. oth Kirby, A.M. oth Enthalten in Saunders Meyer, Theresa ELSEVIER Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory 2022 a journal of the Royal College of Radiologists [S.l.] (DE-627)ELV009071989 volume:34 year:2022 number:8 pages:526-533 extent:8 https://doi.org/10.1016/j.clon.2022.03.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO SSG-OPC-GEO 38.73 Geodäsie VZ 74.41 Luftaufnahmen Photogrammetrie VZ AR 34 2022 8 526-533 8 |
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10.1016/j.clon.2022.03.020 doi /cbs_pica/cbs_olc/import_discovery/elsevier/einzuspielen/GBV00000000001825.pica (DE-627)ELV058296247 (ELSEVIER)S0936-6555(22)00175-3 DE-627 ger DE-627 rakwb eng 550 VZ 38.73 bkl 74.41 bkl Ranger, A. verfasserin aut A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain 2022transfer abstract 8 nicht spezifiziert zzz rdacontent nicht spezifiziert z rdamedia nicht spezifiziert zu rdacarrier Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. VMAT Elsevier Breast radiotherapy Elsevier toxicity breast radiotherapy Elsevier heart-sparing radiotherapy Elsevier Dunlop, A. oth Hansen, V.N. oth Princewill, G. oth Landeg, S. oth Donovan, E.M. oth Harris, E.J. oth McNair, H.A. oth Haviland, J. oth Kirby, A.M. oth Enthalten in Saunders Meyer, Theresa ELSEVIER Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory 2022 a journal of the Royal College of Radiologists [S.l.] (DE-627)ELV009071989 volume:34 year:2022 number:8 pages:526-533 extent:8 https://doi.org/10.1016/j.clon.2022.03.020 Volltext GBV_USEFLAG_U GBV_ELV SYSFLAG_U SSG-OPC-GGO SSG-OPC-GEO 38.73 Geodäsie VZ 74.41 Luftaufnahmen Photogrammetrie VZ AR 34 2022 8 526-533 8 |
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Geometric BIM verification of indoor construction sites by photogrammetric point clouds and evidence theory |
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a randomised phase ii clinical trial comparing the deliverability and acute toxicity of wide tangent versus volumetric modulated arc therapy to the breast and internal mammary chain |
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A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain |
abstract |
Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. |
abstractGer |
Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. |
abstract_unstemmed |
Inclusion of the internal mammary chain in the radiotherapy target volume (IMC-RT) improves disease-free and overall survival in higher risk breast cancer patients, but increases radiation doses to heart and lungs. Dosimetric data show that either modified wide-tangential fields (WT) or volumetric modulated arc therapy (VMAT) together with [AQ1]voluntary deep inspiration breath hold (vDIBH) keep mean heart doses below 4 Gy in most patients. However, the impact on departmental resources has not yet been documented. This phase II clinical trial compared the time taken to deliver IMC-RT using either WT and vDIBH or VMAT and vDIBH, together with planning time, dosimetry, set-up reproducibility and toxicity. |
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A Randomised Phase II Clinical Trial Comparing the Deliverability and Acute Toxicity of Wide Tangent versus Volumetric Modulated Arc Therapy to the Breast and Internal Mammary Chain |
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