Blocking CD47 promotes antitumour immunity through CD103+ dendritic cell–NK cell axis in murine hepatocellular carcinoma model
The CD47–signal regulatory protein α (SIRPα) axis inhibits dendritic cell (DC) phagocytosis and contributes to immune evasion. However, the behaviour of DCs and the potential crosstalk between DCs and natural killer (NK) cells in the hepatocellular carcinoma (HCC) microenvironment after CD47 blockad...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Wang, Shuai [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
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| Schlagwörter: |
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| Umfang: |
12 |
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| Übergeordnetes Werk: |
Enthalten in: Identification of the antigenic region of - Abdelbaky, Hanan H. ELSEVIER, 2018, official journal of the European Association for the Study of the Liver, Amsterdam [u.a.] |
|---|---|
| Übergeordnetes Werk: |
volume:77 ; year:2022 ; number:2 ; pages:467-478 ; extent:12 |
| Links: |
|---|
| DOI / URN: |
10.1016/j.jhep.2022.03.011 |
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ELV05836952X |
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blocking cd47 promotes antitumour immunity through cd103+ dendritic cell–nk cell axis in murine hepatocellular carcinoma model |
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Blocking CD47 promotes antitumour immunity through CD103+ dendritic cell–NK cell axis in murine hepatocellular carcinoma model |
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The CD47–signal regulatory protein α (SIRPα) axis inhibits dendritic cell (DC) phagocytosis and contributes to immune evasion. However, the behaviour of DCs and the potential crosstalk between DCs and natural killer (NK) cells in the hepatocellular carcinoma (HCC) microenvironment after CD47 blockade remain unclear. |
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The CD47–signal regulatory protein α (SIRPα) axis inhibits dendritic cell (DC) phagocytosis and contributes to immune evasion. However, the behaviour of DCs and the potential crosstalk between DCs and natural killer (NK) cells in the hepatocellular carcinoma (HCC) microenvironment after CD47 blockade remain unclear. |
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The CD47–signal regulatory protein α (SIRPα) axis inhibits dendritic cell (DC) phagocytosis and contributes to immune evasion. However, the behaviour of DCs and the potential crosstalk between DCs and natural killer (NK) cells in the hepatocellular carcinoma (HCC) microenvironment after CD47 blockade remain unclear. |
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Wu, Qinchuan Chen, Tianchi Su, Rong Pan, Caixu Qian, Junjie Huang, Hechen Yin, Shengyong Xie, Haiyang Zhou, Lin Zheng, Shusen |
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Wu, Qinchuan Chen, Tianchi Su, Rong Pan, Caixu Qian, Junjie Huang, Hechen Yin, Shengyong Xie, Haiyang Zhou, Lin Zheng, Shusen |
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10.1016/j.jhep.2022.03.011 |
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2024-07-06T18:49:18.197Z |
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