A Local Genetic Correlation Analysis Provides Biological Insights Into the Shared Genetic Architecture of Psychiatric and Substance Use Phenotypes

Global genetic correlation analysis has provided valuable insight into the shared genetic basis between psychiatric and substance use disorders. However, little is known about which regions disproportionately contribute to the global correlation.

Gespeichert in:
Autor*in:

Gerring, Zachary F. [verfasserIn]

Thorp, Jackson G.

Gamazon, Eric R.

Derks, Eske M.

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2022

Schlagwörter:

Substance use disorder

Genome-wide association study

Transcriptome-wide association study

Local genetic correlation

Genetic correlation

Psychiatric disorder

Umfang:

9

Übergeordnetes Werk:

Enthalten in: Iptakalim induces mitochondria-dependent apoptosis in hypoxic rat pulmonary arterial smooth muscle cells - Xu, Qi ELSEVIER, 2016, a journal of psychiatric neuroscience : a publication of the Society of Biological Psychiatry, Amsterdam [u.a.]

Übergeordnetes Werk:

volume:92 ; year:2022 ; number:7 ; day:1 ; month:10 ; pages:583-591 ; extent:9

Links:

Volltext

DOI / URN:

10.1016/j.biopsych.2022.03.001

Katalog-ID:

ELV058799877

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